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Luteinizing hormone (LH), a gonadotropin, stimulates the gonads - in males, the testes, and in females, the ovaries. It is essential for reproduction, and secreted from cells in the anterior pituita...
Viruses are implicated in the causes of some cancers, and may in time offer potential therapy for other forms of cancer. An oncovirus is a virus that can cause cancer. Worldwide, the WHO Internati...
Thrombopoiesis stimulating agents are under evaluation for treatment of idiopathic thrombocytopenic purpura (ITP) and for prevention of severe thrombocytopenia induced by chemotherapy.
ETS2101 (dexanabinol) is a synthetic cannabinoid previously studied in trauma patients. Its anti-cancer potential was identified by e-Therapeutics’ network pharmacology platform. This revealed...
What misperceptions about treatment for anabolic steroid-induced hypogonadism are found on the internet? Clinical Endocrinology
Treatment-induced neuropathy of diabetes may occur after the imposition of strict glycemic control, and may be more common then previously thought; but its mechanism is still not fully understood. B...
Maintaining steroid-free remission in children with idiopathic nephrotic syndrome is an important goal of therapy. A new trial provides evidence that mycophenolate mofetil can be added to the list of ...
A new study from The University of Texas Medical Branch at Galveston has uncovered a mechanism that is central to becoming allergic to ragweed pollen and developing allergic asthma or seasonal nasal a...
AMRI has bought Spanish contractor Gadea Pharmaceutical Group for $174m (€160m) to add muscle to its steroid API business and sign up more customers outside the US.
(World Scientific) In his forthcoming book, 'New Theories and Predictions on the Ozone Hole and Climate Change', Professor Lu quantifies the contributions of the cosmic-ray-driven electron-induced-rea...
This Viewpoint lists some recommendations to improve epidural steroid injections that were developed by a multidisciplinary working group.
Researchers have identified a new mechanism that the tumor suppressor protein p53 uses to trigger cell death via apoptosis and have shown how the process could be harnessed to kill cancer cells. St. J...
To determine the prevalence, risk factors and the severity of visual loss caused by steroid-induced glaucoma (SIG) among children.
Background: Leukocytosis is a powerful predictor of incident chronic kidney disease (CKD) and related outcomes. However, the association between periodontitis measures and increased leukocytosis in th...
Cell division is controlled by a multitude of protein enzymes, but little is known about roles of metabolites in this mechanism. Here, we show that pregnenolone (P5), a steroid that is produced from c...
The aim of our study was to analyze the epidemiological profile and outcome of steroid-induced ocular hypertension in children below 12 years of age in a tertiary eye center.
Data indicates that some steroid derivatives may induce changes on glucose levels; nevertheless, data are very confusing. Therefore, more pharmacological data are needed to characterize the activity i...