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Debate exists regarding the safety of metformin and the risk of metformin-associated lactic acidosis, particularly in the setting of kidney dysfunction. Data from two studies examining the interplay b...
What role could hematological markers potentially play in the evaluation of hidradenitis suppurativa? Wounds
(HealthDay)—A novel score can assess the severity of hidradenitis suppurativa (HS), according to a study published online June 21 in the British Journal of Dermatology.
(MedPage Today) -- Findings don't support metformin in long-standing type 1 diabetes
Nature.comGut microbiota Trust your gut — metformin and diabetesNature.comThe mechanism of action of metformin — an anti-diabetic drug that is widely used to treat type 2 diabetes mellitus (T2DM) ...
This Medical Letter review summarizes the clinical study evidence and adverse effects of metformin treatment for individuals at risk for type 2 diabetes.
Researchers focusing on the common debilitating skin disease Hidradenitis suppurativa (HS), which causes deep, painful lesions and leads to a poor quality of life have isolated new treatment options a...
The American Diabetes Association (ADA) recommends metformin as the first-line treatment for type 2 diabetes. Metformin monotherapy should be initiated at the time of diagnosis for most patients unles...
Metformin is the most widely prescribed drug for patients with type 2 diabetes mellitus and the first-line pharmacologic option as supported by multiple international guidelines, yet a rather large pr...
Which treatments have been shown to be effective in randomized clinical trials (RCTs) for hidradenitis suppurativa (HS) in adults?
A 56 year-old man presented to our Hidradenitis Clinic with an exophytic, bovine-red, ulcerated plaque in the left axillae (figure 1). He reported that he was diagnosed with hidradenitis suppurativa w...
Metformin is widely used in the treatment of type 2 diabetes (T2D), but its mechanism of action is poorly defined. Recent evidence implicates the gut microbiota as a site of metformin action. In a dou...
The efficacy and safety of seven regimens based on metformin (placebo plus metformin, dapagliflozin plus metformin, vildagliptin plus metformin, saxagliptin plus metformin, empagliflozin plus metformi...