Search Results for "Microcephaly Lifespan"

21:04 EDT 31st October 2014 | BioPortfolio

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Mutations in PLK4, encoding a master regulator of centriole biogenesis, cause microcephaly, growth failure and retinopathy

Andrew Jackson, Peter Nürnberg and colleagues identify mutations in PLK4 and TUBGCP6 in individuals with microcephaly, primordial dwarfism, retinopathy and other congenital anomalies. These findings ...

Compound heterozygous BRAT1 mutations cause familial Ohtahara syndrome with hypertonia and microcephaly

Blocking pain receptors extends lifespan, boosts metabolism in mice

(University of California - Berkeley) Chronic pain is known to shorten lifespan, and pain tends to increase with age. But is there a relationship between pain and longevity? UC Berkeley and Salk resea...

Blocking pain receptors found to extend lifespan in mammals

Blocking a pain receptor in mice not only extends their lifespan, it also gives them a more youthful metabolism, including an improved insulin response that allows them to deal better with high blood ...

In utero gene therapy rescues microcephaly caused by Pqbp1-hypofunction in neural stem progenitor cells

Japan women world's longest-lived as male lifespan tops 80

Japanese men's life expectancy rose above 80 for the first time in 2013, but was still several years below that of their female counterparts, whose lifespan was the world's longest, figures released T...

Extreme obesity cuts lifespan more than smoking-study

NEW YORK (Reuters) - That obesity can cut life short by causing strokes and other illnesses comes as no surprise, but a study reported on Tuesday quantifies the toll: The most extreme cases cut a pers...

Extreme obesity cuts lifespan more than smoking: study

NEW YORK (Reuters) - That obesity can cut life short by causing strokes and other illnesses comes as no surprise, but a study reported on Tuesday quantifies the toll: The most extreme cases cut a pers...

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Microcephaly-chorioretinopathy syndrome, autosomal recessive form. A case report.

The autosomal recessive form of microcephaly-chorioretinopathy syndrome is a rare genetic condition that is considered to be an important differential diagnosis with congenital toxoplasmosis.

Divergence in Age Patterns of Mortality Change Drives International Divergence in Lifespan Inequality.

In the past six decades, lifespan inequality has varied greatly within and among countries even while life expectancy has continued to increase. How and why does mortality change generate this diversi...

Plasticity of lifespan: a reaction norm perspective.

It is a well-appreciated fact that in many organisms the process of ageing reacts highly plastically, so that lifespan increases or decreases when the environment changes. The perhaps best-known examp...

Mutations in PLK4, encoding a master regulator of centriole biogenesis, cause microcephaly, growth failure and retinopathy.

Centrioles are essential for ciliogenesis. However, mutations in centriole biogenesis genes have been reported in primary microcephaly and Seckel syndrome, disorders without the hallmark clinical feat...

The dietary proportion of essential amino acids and Sir2 influence lifespan in the honeybee.

Dietary essential amino acids have an important influence on the lifespan and fitness of animals. The expression of the NAD(+)-dependent histone deacetylase, Sir2, can be influenced by diet, but its r...

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