Search Results for "Microcephaly Lifespan"

19:14 EST 1st February 2015 | BioPortfolio

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Mutations in PLK4, encoding a master regulator of centriole biogenesis, cause microcephaly, growth failure and retinopathy

Andrew Jackson, Peter Nürnberg and colleagues identify mutations in PLK4 and TUBGCP6 in individuals with microcephaly, primordial dwarfism, retinopathy and other congenital anomalies. These findings ...

A syndrome of congenital microcephaly, intellectual disability and dysmorphism with a homozygous mutation in FRMD4A

Compound heterozygous BRAT1 mutations cause familial Ohtahara syndrome with hypertonia and microcephaly

Prolonging lifespan: Researchers create 'Methuselah fly' by selecting best cells

Scientists have managed to considerably prolong the lifespan of flies by activating a gene which destroys unhealthy cells. The results could also open new possibilities in human anti-aging research.

In utero gene therapy rescues microcephaly caused by Pqbp1-hypofunction in neural stem progenitor cells

Ibuprofen leads to extended lifespan, study shows

COLLEGE STATION -- Regular doses of ibuprofen extended the lifespan of multiple species, according to research published in Public Library of Science-Genetics. "We first used baker's yeast, which is a...

Japan women world's longest-lived as male lifespan tops 80

Japanese men's life expectancy rose above 80 for the first time in 2013, but was still several years below that of their female counterparts, whose lifespan was the world's longest, figures released T...

Ibuprofen use leads to extended lifespan in several species, study shows

A common over-the-counter drug that tackles pain and fever may also hold keys to a longer, healthier life, according to a Texas A&M AgriLife Research scientist. Regular doses of ibuprofen extended the...

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Microcephaly-chorioretinopathy syndrome, autosomal recessive form. A case report.

The autosomal recessive form of microcephaly-chorioretinopathy syndrome is a rare genetic condition that is considered to be an important differential diagnosis with congenital toxoplasmosis.

PCH-2 regulates Caenorhabditis elegans lifespan.

Components or downstream targets of many signaling pathways such as Insulin/IGF-1 and TOR, as well as genes involved in cellular metabolism and bioenergetics can extend worm lifespan 20% or more. The ...

Mutations in PLK4, encoding a master regulator of centriole biogenesis, cause microcephaly, growth failure and retinopathy.

Centrioles are essential for ciliogenesis. However, mutations in centriole biogenesis genes have been reported in primary microcephaly and Seckel syndrome, disorders without the hallmark clinical feat...

Divergence in Age Patterns of Mortality Change Drives International Divergence in Lifespan Inequality.

In the past six decades, lifespan inequality has varied greatly within and among countries even while life expectancy has continued to increase. How and why does mortality change generate this diversi...

Plasticity of lifespan: a reaction norm perspective.

It is a well-appreciated fact that in many organisms the process of ageing reacts highly plastically, so that lifespan increases or decreases when the environment changes. The perhaps best-known examp...

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