HHMI News: Mutations Point the Way to New Leukemia Drugs
18 Jul 2006 ... New research indicates that drugs that target a cell growth pathway known as ... Thus, the JAK2 pathway is an important player in leukemia. ...
http://www.hhmi.org/news/pikman_gilliland_levine20060718.htm...
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Molecularly targeted therapy: JAK2 inhibitor restores balance in ...
Now, Wernig and colleagues assessed the safety and efficacy of a new, ... The drug inhibited phosphorylation of JAK2 downstream signalling factors such as ...
http://www.nature.com/nrd/journal/v7/n6/full/nrd2599.html...
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Cytopia Scientific Presentations on JAK2 Inhibitor Program
About Cytopia Cytopia Ltd is an Australian biotechnology company focused on the discovery and development of new drugs to treat cancer and other diseases. ...
http://www.prnewswire.com/cgi-bin/stories.pl?ACCT=104&STORY=...
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Leukemia - Comparison of mutated ABL1 and JAK2 as oncogenes and ...
New experimental drugs must be considered under certain circumstances, ..... Bross-Bach U, Kanz L, Brossart P. Detection of a new JAK2 D620E mutation in ...
http://www.nature.com/leu/journal/v22/n7/full/leu2008133a.ht...
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Cytopia scientific presentations on JAK2 inhibitor program
16 Oct 2008 ... Cytopia is a world leader in JAK2 kinase chemistry and holds a broad range of JAK2 ... of new drugs to treat cancer and other diseases. ...
http://www.cytopia.com.au/documents/Cytopiascientificpresent...
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Mutations Point the Way to New Leukemia Drugs
JAK2 normally encodes a protein that helps control the production of new ... disease, so it may be a good model for testing drugs against leukemia," ...
http://www.hhmi.org/news/pdf/pikman_gilliland_levine20060718...
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Cytopia Limited Appoints Study Chairman for JAK2 Clinical Trial ...
29 Jul 2008 ... It is anticipated that an Investigational New Drug application will be ... Cytopia is a world leader in JAK2 kinase chemistry and holds a ...
http://www.biospace.com/news_story.aspx?NewsEntityId=105002...
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Leptin Inhibits Seizures; Study May Lead to New Treatments for ...
13 Mar 2008 ... A new study shows that leptin, a hormone normally associated with eating ... If so, drugs that increase the levels of JAK2 and P13K might be ...
http://www.ninds.nih.gov/news_and_events/news_articles/news_...
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Leukemia - JAK2 inhibitor therapy in myeloproliferative disorders ...
... Bross-Bach U, Kanz L, Brossart P. Detection of a new JAK2 D620E mutation in ..... Inhibition of drug-resistant mutants of ABL, KIT, and EGF receptor ...
http://www.nature.com/leu/journal/v22/n1/full/2404948a.html...
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HHMI News: New Drug Targets Three Kinds of Leukemia
7 Apr 2008 ... JAK2 produces an enzyme that drives proliferation of blood cells in the bone ... Mutations Point the Way to New Leukemia Drugs (07.17.06) ...
http://www.hhmi.org/news/gilliland20080407.html...
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