p21-activated kinase (PAK1) is phosphorylated and activated by 3 ...
In this study, we show that phosphorylated 3-phosphoinositide-dependent kinase 1 (PDK1) phosphorylates p21-activated kinase 1 (PAK1) in the presence of ...
http://www.ncbi.nlm.nih.gov/pubmed/10995762...
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Role of p21-activated kinase pathway defects in the cognitive ...
Because mutation of p21-activated kinase (PAK) can lead to mental retardation and because PAK-cofilin signaling is critical in dendritic spine morphogenesis ...
http://www.nature.com/neuro/journal/v9/n2/abs/nn1630.html...
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Activation of p21-activated kinase 6 by MAP kinase...[J Biol Chem ...
The p21-activated kinases (PAKs) contain an N-terminal Cdc42/Rac interactive binding domain, which in the group 1 PAKs (PAK1, 2, and 3) regulates the ...
http://www.ncbi.nlm.nih.gov/pubmed/15550393...
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Membrane targeting of p21-activated kinase 1 (PAK1) induces ...
Rho-family GTPases regulate cytoskeletal dynamics in various cell types. p21- activated kinase 1 (PAK1) is one of the downstream effectors of Rac and Cdc42 ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=11...
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Sequence analysis of P21-activated kinase 3 (PAK3) in chronic ...
The P21-activated kinase PAK3 is critical for cognitive development and truncating mutations cause non-syndromic mental retardation (MR). ...
http://www.ncbi.nlm.nih.gov/pubmed/18805672...
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Oncogene - P21-activated kinase is required for mitotic ...
Polo-like kinase 1 (Plk1) activity is mediated by P21-activated kinase (Pak)- induced ..... A p21-activated kinase-controlled metabolic switch up-regulates ...
http://www.nature.com/onc/journal/v27/n36/full/onc2008131a.h...
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p21-activated kinase links Rac/Cdc42 signaling to merlin.
Furthermore, we demonstrate that merlin phosphorylation is mediated by p21- activated kinase (Pak), a common downstream target of both Rac and Cdc42. Both in ...
http://www.ncbi.nlm.nih.gov/pubmed/11719502...
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Oncogene - P21-activated kinase is required for mitotic ...
21 Apr 2008 ... A p21-activated kinase-controlled metabolic switch up-regulates ... Cell cycle- regulated phosphorylation of p21-activated kinase 1. ...
http://www.nature.com/onc/journal/vaop/ncurrent/full/onc2008...
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A novel p21-activated kinase binds the actin and microtubule ...
Here, we demonstrate that a novel Cdc42/Rac effector, X-p21-activated kinase ( PAK)5, colocalizes and binds to both the actin and MT networks and that its ...
http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&uid=11733...
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Oncogene - Abstract of article: The kinase-inhibitory domain of ...
p21-activated kinase 1 (PAK1) is a mediator of downstream signaling from the small GTPases Rac and Cdc42. In its inactive state, PAK1 forms a homodimer ...
http://www.nature.com/onc/journal/v26/n12/abs/1209983a.html...
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