p21 and drug development Pages on BioPortfolio:

BioPortfolio - CDKN1A - cyclin-dependent kinase inhibitor 1A (p21 ...
... Biotechnology Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease .... CDKN1A Antibody Wild type p53 activated fragment-1 (p21) ...
http://www.bioportfolio.com/gene/1026-CDKN1A.html...

BioPortfolio Biotechnology BioNews : live article
... Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease ... As previously reported, p23 is processed to form p21 in insect as well as in ...
http://www.bioportfolio.co.uk/cgi-bin/dialogserver.exe?CMD=h...

BioPortfolio - p21-Activated Kinases
p21-Activated Kinases - BioPortfolio - Indepth. ... BioPortfolio Biotechnology Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease ...
http://www.bioportfolio.com/indepth/p21-Activated_Kinases.ht...

BioPortfolio Biotechnology BioNews : live article
... Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease ... In this procedure, p21 was delivered using a recombinant adenovirus to ocular ...
http://www.bioportfolio.co.uk/cgi-bin/dialogserver.exe?CMD=h...

BioPortfolio - PAK1 - p21/Cdc42/Rac1-activated kinase 1 (STE20 ...
... Biotechnology Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease ... PAK1 is a member of the p21-activated kinase (PAK) family of. ...
http://www.bioportfolio.com/gene/5058-PAK1.html...

BioPortfolio "fragile site, BrdU type, common, fra(9)(p21)" Antibody
Biotechnology Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease and ... updated: 16/05/2001 matching: fragil site type common 9 p21 ...
http://www.bioportfolio.co.uk/antibody/fragile%20site,%20Brd...

BioPortfolio - p21 oncogene science
p21 oncogene science - BioPortfolio. ... Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease .... factor 4 (heparin secretory transforming ...
http://www.bioportfolio.com/search/p21_oncogene_science.html...

BioPortfolio Biotechnology BioNews : live article
... cell cycle regulators p21 and p57 function by a similar sequential, ... This article was prepared by Drug Week editors from staff and other reports. ...
http://www.bioportfolio.co.uk/cgi-bin/dialogserver.exe?CMD=h...

BioPortfolio - PAK2 - p21 (CDKN1A)-activated kinase 2
The development of anti-virals has blunted the AIDS epidemic in the. ... The four mammalian splice variants encoded by the p21-activated kinase 3 gene have
...
http://www.bioportfolio.com/gene/5062-PAK2.html...

BioPortfolio "p21(CDKN1A)-activated kinase 7" Antibody
... Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease ... Current Search: p21: 4886, cdkn1a: 4108, activ: 76139, kinas: 35812, 7: 118763
...
http://www.bioportfolio.co.uk/antibody/p21(CDKN1A)-activated...

Results from other life science and pharmaceutical sites:

Drug 9AA reactivates p21/Waf1 and Inhibits HIV-1 progeny formation
Drug 9AA reactivates the p53 and p21/waf1 pathways in HIV-1 infected cells ..... inhibitors and their interaction with RT for antiviral drug development. ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=23...

At a glance : p21-activated kinases in cancer : Nature Reviews Cancer
p21 activated kinases (Paks) are a family of conserved non-receptor ... Drug- discovery efforts have led to the development of several direct and indirect ...
http://www.nature.com/nrc/journal/v6/n6/execsumm/nrc1892.htm...

Differential roles of p21(Waf1) and p27(Kip1) in modulating ...
Differential roles of p21(Waf1) and p27(Kip1) in modulating chemosensitivity and their possible application in drug discovery studies. ...
http://www.ncbi.nlm.nih.gov/pubmed/11641417...

Kidney International - Abstract of article: Reduced p21, p27 and ...
Genetic disorders – Development. Kidney International (2002) 62, ... Reduced p21 , p27 and vitamin D receptor in the nodular hyperplasia in patients with ...
http://www.nature.com/ki/journal/v62/n4/abs/4493215a.html...

Effects of antisense p21 (WAF1/CIP1/MDA6) expression on the ...
Development · Drug Discovery · Drug Discovery ... The p21MDA6 gene product induces cell cycle arrest in p53-null human leukemic cells exposed to ...
http://www.nature.com/leu/journal/v11/n4/abs/2400625a.html...

Kidney International - Abstract of article: Differential ...
Recent studies have suggested a role for the cyclin kinase inhibitor p21 in the development of polycystic kidney disease (PKD) in mice lacking PKD1. ...
http://www.nature.com/ki/journal/v67/n2/abs/4495065a.html...

Crystal Structures of the p21-Activated Kinases PAK4, PAK5, and ...
Targeting inactive conformations of kinases led to the development of highly selective inhibitors. The anticancer drug Gleevec, for instance, ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=18...

Oncogene - Abstract of article: In vivo regulation of p21 by the ...
Our earlier studies identified the cyclin-dependent kinase inhibitor p21 as a transcriptional target of the ... Head of Department - Drug Discovery Biology
...
http://www.nature.com/onc/journal/v26/n30/abs/1210223a.html...

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