Leukemia - Gadd45a acts as a modifier locus for lymphoblastic lymphoma
These results indicate that Gadd45a may act as modifier locus for T-cell LBL, .... and Gadd45a-/-p53-/- animals had similar frequencies of hemangiosarcoma,
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http://www.nature.com/leu/journal/v19/n5/full/2403711a.html...
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Spontaneous hemangiosarcoma in the tail of a Long-...[Lab Anim Sci ...
[Acta Pathol Jpn. 1978]; Presence of a modifier gene(s) affecting early renal ... Protein (RefSeq) Links, Protein (Weighted) Links, Protein Cluster Links ...
http://www.ncbi.nlm.nih.gov/pubmed/8028288...
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Oncogene - Distinct roles for p53, p27Kip1, and p21Cip1 during ...
Sarcomas (rhabdomyosarcoma, osteosarcoma, hemangiosarcoma, and poorly .... This suggests a hierachical relationship, with p27 as a modifier of mutant ...
http://www.nature.com/onc/journal/v23/n4/full/1207220a.html...
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Impact of ionizing radiation and genetic backgroun...[Cancer Res ...
We report here that modifier alleles present in the BALB/c strain increase the incidence of hemangiosarcomas [15 of 53 (28.3%); P = 0.0007] in p53(-/-) mice
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http://www.ncbi.nlm.nih.gov/pubmed/11522657...
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Cooperative action of germ-line mutations in decorin and p53 ...
Moreover, exogenous decorin proteoglycan or its protein core significantly ..... In only one animal, a high-grade hemangiosarcoma was identified in the ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=15...
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NTP Toxicology and Carcinogenesis Studies of 1,3-B...[Natl Toxicol ...
Hemangiosarcomas of the heart occurred at increased incidences in exposed males .... Protein (RefSeq) Links, Protein (Weighted) Links, Protein Cluster Links ...
http://www.ncbi.nlm.nih.gov/pubmed/12748715...
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Oncogene - Ink4c is dispensable for tumor suppression in Myc ...
The p18Ink4c protein acts as a tumor suppressor in some cell contexts. ..... Hemangiosarcomas, medulloblastomas, and other tumors in Ink4c/p53-null mice. ...
http://www.nature.com/onc/journal/v26/n20/full/1210104a.html...
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Loss of p53 Sensitizes Mice with a Mutation in Ccm1 (KRIT1) to ...
Both KRIT1 (the protein product of CCM1) and Malcavernin (product of CCM2) may .... rules out hemangiosarcoma, which has been reported in a subset of Trp53 ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=16...
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PubMed Result
Modulation of gap junction transcript and protein expression during pregnancy in the rat. ... Connexin37: a potential modifier gene of inflammatory disease. ...
http://www.ncbi.nlm.nih.gov/pubmed/16677656,17531234,1598249...
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Cell Death and Differentiation - Dissecting p53 tumor suppressor ...
The p53 protein is a frequent target of mutation or functional inactivation in .... The p53 protein is stabilized and activated in response to a variety of ...
http://www.nature.com/cdd/journal/v13/n6/full/4401902a.html...
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