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Mature B-cell neoplasms arise in B-cells that have entered germinal centers within lymph nodes as part of the immune response. They display great heterogeneity at the clinical, pathologic, and genet...
Sinus node dysfunction refers to a number of conditions producing physiologically inappropriate atrial rates. Symptoms may be minimal or include weakness, palpitations, and syncope. Diagnosis is by ...
Radioguided sentinel lymph node biopsy detected occult cervical lymph node metastases in about one-half of patients with thyroid nodules suspicious for papillary thyroid carcinoma, altering the manage...
Breast cancer patients over 50 years old could be spared invasive procedures by use of stratification based on tumour size and molecular characteristics, including Ki67. The cell proliferation index K...
Examining at least 18 lymph nodes after neck dissection is associated with significantly longer overall survival (OS) in patients with head and neck cancer, regardless of whether they are clinically n...
Can lymph node ratio predict survival and recurrence in patients with NSCLC? Translational Lung Cancer Research
CLND as standard of care for patients with SLN-positive metastatic melanoma is supported by a wealth of compelling prospective data.
Ironically, the patients who can benefit the most from CLND in terms of regional nodal basin disease control are the patients who are least likely to experience a survival benefit.
The family Marseilleviridae is a new clade of giant viruses whose original member, marseillevirus, was described in 2009. These viruses were isolated using Acanthamoeba spp primarily from the environm...
Lymph node status independently correlates with overall survival after chemotherapy and resection; response to preoperative chemotherapy does not.
Regional lymph node metastases in colorectal cancer (CRC) decrease outcome. Whether nodal metastases function as a biomarker, i.e. as a sign of advanced disease, or are in fact involved in the metasta...
Since the introduction of the sentinel node technique for breast cancer in the 1990s patient's morbidity was reduced. Tracer uptake is known to be dependent from lymph node integrity and activity of m...
-Sentinel lymph node biopsy has been established as the new standard of care for axillary staging in most patients with invasive breast carcinoma. Historically, all patients with a positive sentinel l...
Regional lymph node status is an important prognostic indicator of tumor aggressiveness. However, early diagnosis of metastasis using intranodal pressure, at a stage when lymph node size has not chang...
Whether patients with positive SLNB should undergo complete lymph node dissection (CLND) is an important unanswered clinical question.