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The first three-dimensional image of a key protein known to be involved in the development of blood and other cancers has been created by scientists. This discovery showed the protein, called Trib1, p...
Protein expression is a dark art. So much so, I think it is on the Defense Against the Dark Arts syllabus at Hogwarts! It can be a lonely pursuit to get the protein to […]
(University of Otago) Scientists from New Zealand and Australia have created the first three-dimensional image of a key protein involved in the development of blood and other cancers. The researchers ...
Findings provide new insights into how the protein regulates cell growth and how mutations in the gene that encodes the protein can lead to cancer
A small molecule targeting the protein-protein interaction between a chromatin binding protein and an oncogenic transcription factor shows therapeutic potential in a subtype of acute myeloid leukemia.
GENEVA, SWITZERLAND – A new tool for protein digestion is designed to substantially reduce preparation times and associated errors, facilitating fast and reliable analytical results for biopharmace...
A polymeric protein complex consisting of a newly identified magnetoreceptor protein and known magnetoreception-related photoreceptor cryptochromes exhibits spontaneous alignment in magnetic fields.
Protein PEGylation is routinely used to produce molecules with improved pharmacokinetic properties. However, despite their importance, the structure of PEGylated proteins has remained elusive. Now, th...
The differential ability of various milk protein fractions to stimulate muscle protein synthesis (MPS) has been previously described, with whey protein generally considered to be superior to other fra...
Understanding protein-protein interactions and the architecture of protein complexes in which they work is essential to identify their biological role. Protein co-immunoprecipitation (co-IP) is an inv...
PolyC binding protein 1 (PCBP1) is a transcriptional regulator of human mu-opioid receptor (hMOR) gene in the CNS and is also related to cancer/diseases. It possesses multi-roles that can be mediated ...
In view of the increasing interest both in inhibitors of protein-protein interactions and in protein drugs themselves, analysis of the three-dimensional structure of protein-protein complexes is assum...
We describe a method for quantitative monitoring of subcellular protein trafficking using nanoparticle-stabilized nanocapsules for protein delivery. This method provides rapid delivery of the protein ...