Deacetylation of the retinoblastoma tumour suppressor protein by SIRT1
The activity of Rb (retinoblastoma protein) is regulated by phosphorylation .... Santa Cruz Biotechnology), anti-p130 [C-20 (Santa Cruz Biotechnology) or 3F327 ..... Our results suggest that SIRT1 uses a different structural motif that ...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275065/...
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Structural basis for the inactivation of retinoblastoma tumor ...
... South Korea; Department of Biotechnology, Korea University, Seoul, South Korea ... Inactivation of the retinoblastoma (Rb) tumor suppressor by Simian virus 40 ... T antigen may use a chaperone mechanism for its biological function . ...
http://www.nature.com/emboj/journal/v20/n1/abs/7593536a.html...
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Retinoblastoma Loss Modulates DNA Damage Response Favoring Tumor ...
We use this tumor type as a paradigm of oncogenic transformation. ..... Cell Signaling Technology) and p-p38 (polyclonal, Santa Cruz Biotechnology). ...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2573954/...
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Acute mutation of retinoblastoma gene function is sufficient for ...
Acute mutation of retinoblastoma gene function is sufficient for cell cycle re- entry ... Thus, the use of conditional knockout strategies might refine our ...
http://www.nature.com/nature/journal/v424/n6945/abs/nature01...
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Distinct Mechanisms for Repression of RNA Polymerase III ...
The retinoblastoma (RB) protein controls the cell cycle, differentiation, .... ( ChIP) experiments were purchased from Santa Cruz Biotechnology. ..... It is possible that RB also uses these cofactors to regulate U6 transcription. ...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC480882/...
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Structural basis for the inactivation of retinoblastoma tumor ...
... Seoul and 3Department of Biotechnology, Korea University, Seoul, ... Inactivation of the retinoblastoma (Rb) tumor suppressor by Simian virus 40 ( SV40) large ..... From our structural studies, we propose that large T antigen uses a ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=14...
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Intraocular tumor formation of RB reconstituted retinoblastoma cells.
Since retinoblastoma is an eye tumor it also provides further documentation that the use of an orthotopic injection site can be critical when determining ...
http://www.ncbi.nlm.nih.gov/pubmed/1868470...
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Developmental Cell - The Retinoblastoma-Histone Deacetylase 3 ...
... with chemotherapeutic agents in current use for specific cancers. ... The retinoblastoma protein (RB) has previously been shown to facilitate adipocyte ... Neuron, Structure, Trends in Biochemical Sciences, Trends in Biotechnology ...
http://www.cell.com/developmental-cell/abstract/S1534-5807(0...
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A thyroid hormone receptor coactivator negatively regulated by the ...
Department of Molecular Medicine and Institute of Biotechnology, University of Texas ... The retinoblastoma protein (Rb) plays a critical role in cell ... The protein uses two distinct regions to bind Rb and thyroid hormone receptor ...
http://www.ncbi.nlm.nih.gov/pubmed/9256431...
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Characterization of protein kinase C β isoform's action on ...
Association of PKCβ2 isoform with retinoblastoma protein was discovered in ... also been suggested by the use of a PKCβ isoform selective inhibitor, ... In vitro phosphorylation of Rb protein by recombinant PKC (Upstate Biotechnology, ...
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=11...
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