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09:46 EDT 24th June 2017 | BioPortfolio

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FDA Grants Orphan Drug Designation To s DynPort Vaccine Company For Plague Vaccine

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Exploring vaccine safety

When a vaccine is given, there's always a risk of side-effects since it induces an immune response. The BIO-department is involved in the largest vaccine project ever, with the aim to develop new tool...

'Groundbreaking Strides' Made in Zika Vaccine Research

WEDNESDAY, May 10, 2017 -- Development of a Zika vaccine is proceeding rapidly, but it still will be years before such a vaccine is available to the public, says the author of a new report on research...

Plague Vaccine Granted Orphan Drug Designation by FDA

NewsFDA grants orphan drug designation to CSRA's DynPort Vaccine Company for plague vaccine. Plague is an acute disease caused by infection with Y. pestis, a gram-negative bacterium. It currently is ...

Investigational Vaccine Protected Monkeys from HIV-Like Virus

The vaccine adds three more targets to a human vaccine candidate that showed promise

Recommendation against inhaled flu vaccine is good—for now

Recent federal recommendations against offering the inhaled nasal influenza vaccine due to lack of effectiveness could lead to more flu illness in the U.S. if the inhaled vaccine becomes effective aga...

SRI’s Michigan Office Will Help Develop New VEE Vaccine

SRI International, the Menlo Park, CA-based nonprofit contract research giant, is counting on its Michigan office to play a crucial role in the development of a new vaccine. SRI has been awarded two c...

[Comment] Moving forward with Takeda's live chimeric tetravalent dengue vaccine

Several decades of dengue vaccine research have shown how challenging it is to develop a highly efficacious vaccine that protects against all four dengue serotypes (DENV-1–4) for people of all ages....

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Modeling HIV vaccine trials of the future.

Models of implementation of known-effective interventions for HIV prevention indicate that an efficacious vaccine to prevent HIV infection would be critical for controlling the HIV pandemic. Key issue...

Efficacy of Phase 3 Trial of RTS, S/AS01 Malaria Vaccine: The Need for an Alternative Development Plan.

Although vaccines would be the ideal tool for control, prevention, elimination, and eradication of many infectious diseases, developing of parasites vaccines such as malaria vaccine is very complex. T...

Post-hoc analysis of a randomized controlled trial: Diabetes mellitus modifies the efficacy of the 13-valent pneumococcal conjugate vaccine in elderly.

The 13-valent pneumococcal conjugate-vaccine (PCV13) was effective in preventing vaccine-type Community-Acquired Pneumonia (VT-CAP) and Invasive Pneumococcal Disease (VT-IPD) in elderly subjects, but ...

Lactococcus lactis carrying a DNA vaccine coding for the ESAT-6 antigen increases IL-17 cytokine secretion and boosts the BCG vaccine immune response.

A regimen utilizing BCG and another vaccine system as a booster may represent a promising strategy for the development of an efficient tuberculosis vaccine for adults. In a previous work, we confirmed...

Bacillus Calmette-Guérin vaccine complications in Iranian children at a University Hospital.

Although the BCG vaccine remains the only available vaccine, a number of complications from local to systemic adverse reactions can occur.

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