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20:15 EDT 26th April 2015 | BioPortfolio

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Painkiller Tramadol Linked to Low Blood Sugar

MONDAY, Dec. 8, 2014 -- The narcotic painkiller tramadol (Ultram) seems to be associated with an increased risk of dangerously low blood sugar, Canadian researchers report. Tramadol is a narcotic drug...

Drug interaction identified for ondansetron, tramadol

(HealthDay)—In the early postoperative period, ondansetron is associated with increased requirements for tramadol consumption, according to a review and meta-analysis published online Dec. 10 in Ana...

Tramadol associated with increased risk of hospitalization for hypoglycemia

The opioid pain-reliever tramadol appears to be associated with an increased risk of hospitalization for hypoglycemia, a potentially fatal condition caused by low blood sugar, according to a report pu...

Ampio's Vyrix withdraws IPO

The Vyrix Pharmaceutical Inc. subsidiary of Ampio Pharmaceuticals Inc. (NYSE-M:AMPE) withdrew its proposed IPO on NYSE MKT, citing market conditions. In April, Vyrix filed to raise up to $28.8 million...

Coronado Biosciences In-Licenses IV Tramadol, a Phase III Ready Asset, From Revogenex Ireland Ltd.

NEW YORK, Feb. 18, 2015 (GLOBE NEWSWIRE) -- Coronado Biosciences, Inc. (Nasdaq:CNDO) has obtained an exclusive license to an intravenous (IV) formulation of tramadol for the U.S. market from Revogene...

Opioid Linked to Low Blood Sugar

(MedPage Today) -- Tramadol was associated with an increased risk of hospitalization for hypoglycemia.

Pain Med Linked to Hypoglycemia

Tramadol, an opioid analgesic, was associated with an increased risk for hospitalization for hypoglycemia, especially in the first month of use, in a new study. Medscape Medical News

Russian doctor is acquitted of drug trafficking charges for providing opioid to a dying man

A doctor and a pharmacist in Russia have been acquitted of drug trafficking charges for helping a dying man get the pain reliever tramadol, after a three year legal battle, Human Rights Watch has... ...

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Effect of single oral dose of tramadol on gastric secretions pH.

Tramadol is an atypical analgesic agent. It has been shown that intramuscular or intravenous injection tramadol is able to inhibit M3 muscarinic receptors. Tramadol is able to mediate smooth muscles c...

Brain Serotonin Content Regulates the Manifestation of Tramadol-induced Seizures in Rats: Disparity between Tramadol-induced Seizure and Serotonin Syndrome.

Tramadol-induced seizures might be pathologically associated with serotonin syndrome. Here, the authors investigated the relationship between serotonin and the seizure-inducing potential of tramadol.

The Pharmacogenetics of Tramadol.

Tramadol hydrochloride is used worldwide as an analgesic drug with a unique dual function. The metabolic enzymes cytochrome P450 (CYP) 3A4, CYP2B6, and CYP2D6 and the various transporters [adenosine t...

Labour Analgesia When Epidural Is Not a Choice: Tramadol versus Pentazocine.

Background. Parenteral opioids, thus, are still popular for pain relief in labor in many countries throughout the world. Aim. To evaluate and compare the efficacy of intramuscular tramadol and pentazo...

Clinical pharmacokinetics of tramadol and main metabolites in horses undergoing orchiectomy.

Background: Tramadol is a synthetic codeine analogue used as an analgesic in human and veterinary medicine. It is not approved for use in horses, but could represent a valid tool for pain treatment in...

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