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In vitro, animal and human sample studies identified three steroids that could treat iron overload by promoting expression of
Find out how high solute ingestion and excessive fluid intake contributed to this case of polyuria. American Journal of Kidney Diseases
(ETH Zurich) ETH researchers have found that therapeutic iron supplements may be less effective when given in brief intervals: A peptide molecule blocks iron absorption in the intestine even 24 hours ...
Dr Jeffrey Berns urges caution when using intravenous iron to treat iron deficiency anemia in CKD patients who are not on dialysis. Medscape Nephrology
For patients receiving a first dose of an intravenous iron product, iron dextran had more than three times the risk for anaphylaxis as did iron sucrose. Medscape Medical News
(Technical University of Munich (TUM)) Iron deficiency is often an issue in patients with inflammatory bowel diseases. An international and interdisciplinary research group under the aegis of the ZIEL...
Dr Jeffrey Berns discusses inconsistencies in the clinical trial evidence comparing intravenous iron with oral iron in patients with chronic kidney disease not on dialysis. Medscape Nephrology
Monofer (iron isomaltoside; Pharmacosmos) is now indicated for adult patients with iron deficiency when either oral iron preparations are ineffective or cannot be used, or where there is a clinical ne...
Iron deficiency in early life is associated with developmental problems, which may persist until later in life. The question of whether iron repletion after developmental iron deficiency could restore...
Iron overload among hemodialysis patients was previously considered rare but is now an increasingly recognized clinical situation. We analyzed correlations between iron biomarkers and the liver iron c...
Polyuria, defined as daily urine output in excess of 3.0 to 3.5L/d, can occur due to solute or water diuresis. Solute-induced polyuria can be seen in hospitalized patients after a high solute load fro...
We study the diffusion of small solute particles through solvent keeping the solute-solvent interaction repulsive and varying the solvent properties. The study involves computer simulations, developme...
High RPE iron levels have been associated with age-related macular degeneration. Mutation of the ferroxidase ceruloplasmin leads to RPE iron accumulation and degeneration in patients with aceruloplasm...