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In vitro, animal and human sample studies identified three steroids that could treat iron overload by promoting expression of
A new iron preparation added to dialysate may have some advantages over IV iron, but it may have some drawbacks as well. Medscape Nephrology
(ETH Zurich) ETH researchers have found that therapeutic iron supplements may be less effective when given in brief intervals: A peptide molecule blocks iron absorption in the intestine even 24 hours ...
Dr Jeffrey Berns urges caution when using intravenous iron to treat iron deficiency anemia in CKD patients who are not on dialysis. Medscape Nephrology
For patients receiving a first dose of an intravenous iron product, iron dextran had more than three times the risk for anaphylaxis as did iron sucrose. Medscape Medical News
Iron availability plays a decisive role in host-pathogen interaction, and limitation of iron availability to microbes has been characterized as an effective host defense strategy. The identification o...
Iron uptake in plants is limited due to its low solubility in neutral or alkaline soils. This is why plants rely on rhizosphere acidification to increase iron solubility. AtVIT1 gene from Arabidopsis ...
Using iron instead of the scarce ruthenium in light-harvesting complexes is challenging because iron complexes generally have short-lived excited states. Now an iron complex has been developed that ha...
Iron deficiency in early life is associated with developmental problems, which may persist until later in life. The question of whether iron repletion after developmental iron deficiency could restore...
Iron overload among hemodialysis patients was previously considered rare but is now an increasingly recognized clinical situation. We analyzed correlations between iron biomarkers and the liver iron c...
Polyuria, defined as daily urine output in excess of 3.0 to 3.5L/d, can occur due to solute or water diuresis. Solute-induced polyuria can be seen in hospitalized patients after a high solute load fro...
We study the diffusion of small solute particles through solvent keeping the solute-solvent interaction repulsive and varying the solvent properties. The study involves computer simulations, developme...
High RPE iron levels have been associated with age-related macular degeneration. Mutation of the ferroxidase ceruloplasmin leads to RPE iron accumulation and degeneration in patients with aceruloplasm...