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10:10 EDT 1st September 2015 | BioPortfolio

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Gyros Introduces Gyrolab CHO-HCP Kit 1 for Detection and Quantification of Host Cell Proteins in Bioprocessing

Nanoliter-scale kit rapidly and easily detects and quantifies host cell proteins from Chinese hamster ovary cells Gyros AB, a pioneer in miniaturizing and automating immunoassays at nanoliter-scale, t...

Safety and antitumor effect of oncolytic and helper-dependent adenoviruses expressing interleukin-12 variants in a hamster pancreatic cancer model

Intravenously Administered Recombinant Human Type VII Collagen Derived from Chinese Hamster Ovary Cells Reverses the Disease Phenotype in Recessive Dystrophic Epidermolysis Bullosa Mice

Study shows a way to tell if your hamster is happy

(—A pair of researchers at Liverpool John Moores University in the U.K. believe they have found a way to measure happiness in hamsters. In their paper published in Royal Society Open Scien... 2.0: Genome resources and website updates

Chinese hamster ovary (CHO) cells are a major host cell line for the production of therapeutic proteins, and CHO cell and Chinese hamster (CH) genomes have recently been sequenced using next‐generat...

Horizon Discovery consortium lands £6.2mln govt funding

Horizon Discovery (LON:HZD) is part of a group of firms has won £6.2mln of government funding designed to improve the global competitiveness of UK businesses. The consortium is led by the Centre...

Compartment‐specific metabolomics for CHO reveals that ATP pools in mitochondria are much lower than in cytosol

Mammalian cells show a compartmented metabolism. Getting access to subcellular me‐tabolite pools is of high interest to understand the cells' metabolomic state. There‐fore a protocol is developed ...

Optimization of bioprocess conditions improves production of a CHO cell‐derived, bioengineered heparin

Heparin is the most widely used anticoagulant drug in the world today. Heparin is currently produced from animal tissues, primarily porcine intestines. A recent contamination crisis motivated developm...

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Effective cryopreservation of golden Syrian hamster embryos by open pulled straw vitrification.

Golden Syrian hamster embryos are difficult to cryopreserve due to their high sensitivity to cryoprotectants and in vitro handling. The objective of this study is to develop a robust open pulled stra...

Annotation of additional evolutionary conserved microRNAs in CHO cells from updated genomic data.

MicroRNAs are small non-coding RNAs that play a critical role in post-transcriptional control of gene expression. Recent publications of genomic sequencing data from the Chinese Hamster (CGR) and Chin...

A Hamster Model of Diet-Induced Obesity for Preclinical Evaluation of Anti-Obesity, Anti-Diabetic and Lipid Modulating Agents.

Unlike rats and mice, hamsters develop hypercholesterolemia, and hypertriglyceridemia when fed a cholesterol-rich diet. Because hyperlipidemia is a hallmark of human obesity, we aimed to develop and c...

Expression and activity levels of chymase in mast cells of burn wound tissues increase during the healing process in a hamster model.

The present study aimed to investigate the changes in the expression levels and activity of mast cell chymase in the process of burn wound healing in a hamster model of deep second-degree burn. The ha...

HPLC-MS-MS Method Development and Validation of Antileishmanial Agent, S010-0269, in Hamster Serum.

A rapid, sensitive and simple high-performance liquid chromatography-tandem mass spectrometry method was developed and validated for the quantification of the antileishmanial agent, S010-0269, in hams...

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