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21:24 EDT 29th August 2016 | BioPortfolio

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Augmenting Chinese hamster genome assembly by identifying regions of high confidence

Chinese hamster Ovary (CHO) cell lines are the dominant industrial workhorses for therapeutic recombinant protein production. The availability of genome sequence of Chinese hamster and CHO cells will ...

CHO and E. coli Residual DNA Quantification Kit

Product ReleaseBio-Rad’s new ddPCR CHO Residual DNA Quantification Kit and PCR E. coli Residual DNA Quantification Kit allow for direct quantification of host-cell DNA impurities in biopharmace...

Survival of the oldest

The oldest surviving species of vertebrates, such as the cane toad and the California sea lion, which have endured past extreme environmental events, will be more likely to adapt to future climate cha...

Lonza Launches PowerCHO Advance™ Media for Improved Protein-Production Yields

Lonza has launched PowerCHO Advance™ Media, the latest addition to the company’s range of specialized, chemically defined, serum-free media for culturing Chinese Hamster Ovary (CHO) cells....

Biogen, Gates seek new antibody manufacturing techniques

Biogen Inc. (NASDAQ:BIIB) said it will co-fund a project with the Bill & Melinda Gates Foundation to improve production and manufacturing techniques for antibody-based therapies. Biogen said the initi...

Lonza PowerCHO Advance Media

Lonza has launched PowerCHO Advance Media, the latest addition to the company’s range of specialised, chemically defined, serum-free media for culturing Chinese hamster ovary (CHO) cells. The media...

Pharmaceutical Research: Targeted Delivery of Epirubicin to Cancer Cells by Polyvalent Aptamer System in vitro and in vivo

Type: Original PaperPurposeThe clinical use of Epirubicin (Epi), as an anthracycline drug, is limited because of its cardiotoxicity. Here, an Epirubicin (Epi)-modified polyvalent aptamer system (MPAS)...

Bio-Rad ddPCR CHO and E. coli Residual DNA Quantification Kits

Bio-Rad Laboratories has announced the launch of two residual DNA quantification (RDQ) kits to simplify the quantification of host-cell DNA (HCD) in process development, quality control and biomanufac...

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Photoperiod regulates the differential expression of KiSS-1 and GPR54 in various tissues and sexes of striped hamster.

In order to investigate how photoperiod affects the expression of KiSS-1/G-protein-coupled receptor 54 (GPR54), the hypothalamus, the ovaries and testicles of the striped hamster were studied followin...

Development of novel DNA markers for genetic analysis of grey hamsters by cross-species amplification of microsatellites.

The grey hamster has been used in biomedical research for decades. However, effective molecular methods for evaluating the genetic structure of this species are lacking, which hinders its wider usage....

Chemopreventive effect of Toona sinensis leaf extract on 7,12-dimethylbenzaanthracene-induced hamster buccal pouch squamous cell carcinogenesis.

Toona sinensis leaf extract (TSL) has been shown to have anti-tumor effects on cancer cell lines. This study aimed to investigate the chemopreventive potential and the underlying mechanism of TSL duri...

Antibacterial and Solubility Optimization of Thiomuracin A.

Synthetic studies of the antimicrobial secondary metabolite thiomuracin A (1) provided access to analogs in the Northern region (C2-C10). Selective hydrolysis of the C10 amide of lead compound 2 and s...

Quantitative differentiation of normal and scarred tissues using second-harmonic generation microscopy.

The aim of this study was to differentiate normal and scarred hamster cheek pouch samples by applying a quantitative image analysis technique for determining collagen fiber direction and density in se...

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