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18:25 EDT 29th August 2014 | BioPortfolio

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France acts to save endangered hamster

Authorities in the French region of Alsace have launched an action plan to save a hamster facing extinction, more than two years after Europe's top court rapped Paris for neglecting the little rodent.

Hamster-sized deer born in Spain

The latest specimen of the world's tiniest deer—a rare species no bigger than a hamster—has been born in a nature park in southern Spain, conservationists said on Friday.

Evaluation of apoptogenic adenovirus type 5 oncolytic vectors in a Syrian hamster head and neck cancer model

Optimization of heterologous protein production in Chinese hamster ovary cells under overexpression of spliced form of human X-box binding protein

Background: The optimization of protein production is a complex and challenging problem in biotechnology. Different techniques for transcription, translation engineering and the optimization of cell c...

Overexpression of microRNAs enhances recombinant protein production in Chinese hamster ovary cells

MicroRNAs (miRNAs) are short, non‐coding RNAs which can negatively regulate expression of multiple genes at post‐transcriptional levels. Using miRNAs to target multiple genes and pathways is a pro...

Enhancing Recombinant Protein Production of CHO Cells through Over-expression of miR-17

Recombinant production of therapeutic proteins plays an important role in advanced medical care and most of these proteins are produced from Chinese hamster ovary (CHO) cells. Several successful genet...

Improved elongation factor-1 alpha-based vectors for stable high-level expression of heterologous proteins in Chinese hamster ovary cells

Background: Establishing highly productive clonal cell lines with constant productivity over 2-3 months of continuous culture remains a tedious task requiring the screening of tens of thousands of clo...

Pharmaceutical Research: Optimum Topical Delivery of Adrenergic Agonists to Oral Mucosa Vasculature

Type: Original PaperPurposeIdentify an orotopical vehicle to deliver an α-adrenergic vasoconstrictor to submucosal vasculature that is readily palatable to cancer/bone marrow transplant patients that...

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Effect of heavy-ion beam irradiation on the level of serum soluble interleukin-2 receptors in hamster cheek pouch carcinoma model.

Soluble interleukin-2 receptor (sIL-2R) is a glycoprotein derived from α chain of interleukin 2 receptors of mononuclear as well as T-cell membranes. The aims of this study were to detect the changes...

Complete Genome Sequence of Phodopus sungorus Papillomavirus Type 1 (PsPV1), a Novel Member of the Pipapillomavirus Genus, Isolated from a Siberian Hamster.

We report the complete genomic sequence of Phodopus sungorus papillomavirus type 1 (PsPV1), isolated from an anogenital lesion of a Siberian hamster. PsPV1 is taxonomically classified in the genus Pip...

The combination of i-leader truncation and gemcitabine improves oncolytic adenovirus efficacy in an immunocompetent model.

Adenovirus (Ad) i-leader protein is a small protein of unknown function. The C-terminus truncation of the i-leader protein increases Ad release from infected cells and cytotoxicity. In the current stu...

Topical methotrexate pretreatment enhances the therapeutic effect of topical 5-aminolevulinic acid-mediated photodynamic therapy on hamster buccal pouch precancers.

Topical 5-aminolevulinic acid-mediated photodynamic therapy (ALA-PDT) is effective for treatment of human oral precancerous lesions. This animal study aimed to assess whether topical methotrexate (MTX...

Effects of RFRP-3 on reproduction is sex- and developmental status-dependent in the striped hamster (Cricetulus barabensis).

RFamide-related peptides (RFRPs) are orthologous to gonadotropin-inhibitory hormone (GnIH) inhibiting gonadotropin release. There are only two RFRP sequences (RFRP-1 and RFRP-3) encoded in rodents. RF...

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