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A CO-neutral energy production alternative compared to conventional fossil fuel utilization is biohydrogen (H) production. Three basic mechanisms for microbial H production exist: photosynthetic H production, photo-fermentative H production, and dark fermentative H production (DFHP). Despite surmounting reports in literature on the characterization and optimization of DFHP systems, H production ha...
The recent drop in the price of natural gas has rekindled the interests in methanotrophs, the organisms capable of utilizing methane as the sole electron donor and carbon source, as biocatalysts for various industrial applications. As heterologous expression of the methane monooxygenases in more amenable hosts has been proven to be nearly impossible, future success in methanotroph biotechnology la...
This corrects the article DOI: 10.1038/nbt0818-671.
This corrects the article DOI: 10.1038/nbt.4210.
This corrects the article DOI: 10.1038/nbt.3906.
Recent developments in gene-editing technology have enabled scientists to manipulate the human genome in unprecedented ways. One technology in particular, Clustered Regularly Interspaced Short Pallindromic Repeat (CRISPR), has made gene editing more precise and cost-effective than ever before. Indeed, scientists have already shown that CRISPR can eliminate genes linked to life-threatening diseases...
This review presents an update on the current knowledge of the secondary metabolite potential of the major fungal species used in industrial biotechnology, i.e., Aspergillus niger, Aspergillus oryzae, and Trichoderma reesei. These species have a long history of safe use for enzyme production. Like most microorganisms that exist in a challenging environment in nature, these fungi can produce a larg...