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H7N9 Bird Flu Virus - Biotech, Pharma and Life Science Channel

16:33 EST 9th December 2018 | BioPortfolio

Avian influenza A H7 viruses are a group of influenza viruses that normally circulate among birds. The avian influenza A(H7N9) virus is one subgroup among the larger group of H7 viruses. Although some H7 viruses (H7N2, H7N3 and H7N7) have occasionally been found to infect humans, no human infections with H7N9 viruses have been reported until recent reports from China.

News Articles [5 Associated News Articles listed on BioPortfolio]

Medigen Vaccine Biologics Corp 6547 Pharmaceuticals Healthcare Deals and Alliances Profile [Report Updated: 08112018] Prices from USD $250

SummaryMedigen Vaccine Biologics Corp MVC a subsidiary of Medigen Biotechnology Corp is a biopharmaceutical company with focus on the development and production of vaccines and biologics. Its research...

Genentech Announces FDA Approval of XOFLUZA (Baloxavir Marboxil) for Influenza

– First and only single-dose oral medicine approved to treat the flu – – XOFLUZA significantly reduced the duration of flu symptoms compared to placebo – ...

Medigen Vaccine Biologics Corp 6547 Pharmaceuticals Healthcare Deals and Alliances Profile [Report Updated: 12092018] Prices from USD $250

SummaryMedigen Vaccine Biologics Corp MVC a subsidiary of Medigen Biotechnology Corp is a biopharmaceutical company with focus on the development and production of vaccines and biologics. Its research...

Influenza A Virus, H7N9 Subtype Infections Pipeline Review, H1 2018 [Report Updated: 29062018] Prices from USD $2000

Influenza A Virus, H7N9 Subtype Infections Pipeline Review, H1 2018SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Influenza A Virus, H7N9 Subtype Infection...

FDA Grants Priority Review to Genentech’s Baloxavir Marboxil for the Treatment of Influenza

– Influenza, or “flu,” represents a serious threat to public health – globally, annual epidemics result in 3 to 5 million cases of severe disease, millions of hospitalizat...

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Companies [1 Associated Companies listed on BioPortfolio]

Ansun BioPharma

Ansun BioPharma is a clinical stage biopharmaceutical company focused on the development of unique host-directed anti-viral therapies for respiratory viruses. Ansun BioPharma has ...

Clinical Trials [20 Associated Clinical Trials listed on BioPortfolio]

A Study of An Adjuvanted Inactivated H7N9 Influenza Vaccine

The aim of this study is to investigate the immunogenicity and safety of the inactivated whole-virion vaccine for teenagers and adults. The investigators will test the vaccine in particip...

Reactogenicity, Safety and Immunogenicity of a LAIV А/17/Hong Kong/2017/75108 H7N9 Influenza Vaccine

This is a single center phase I, double-blind placebo-controlled study to assess reactogenicity, safety and immunogenicity of a live monovalent A/17/Hong Kong/2017/75108 (H7N9) influenza v...

2017 A/H7N9 IIV Revaccination

This is a Phase II clinical trial in up to 420 males and non-pregnant females, 19 to 70 years of age, inclusive, who are in good health and meet all eligibility criteria. This clinical tri...

Seqirus 2017 H7N9 With/Without MF59 (R) in Healthy Males and Non-pregnant Females, 18-64 Years of Age.

This is a randomized, double-blinded, Phase II study in healthy males and non-pregnant females, 18-64 years of age. This clinical trial is designed to assess the safety, reactogenicity, an...

Safety, Reactogenicity and Immunogenicity of Different Prime-Boost Vaccination Schedules of 2013 and 2017 A/H7N9 Inactivated Influenza Vaccines With or Without AS03 Adjuvant

This is a trial designed to assess the safety, reactogenicity and immunogenicity of one or two doses of monovalent inactivated split influenza 2013 and 2017 A/H7N9 virus vaccines administe...

A Study in Healthy Adults to Assess Priming With Antigenically Mismatched Live Attenuated A/H7N3 Influenza Virus Vaccine Followed by Inactivated A/H7N9 Influenza Virus Vaccine

The purpose of this study is to assess priming with antigenically mismatched live attenuated A/H7N3 influenza virus vaccine followed by inactivated A/H7N9 influenza virus vaccine in health...

A Clinical Trail Of An Adjuvanted Inactivated H7N9 Influenza Vaccine

The aim of this study is to investigate the immunogenicity and safety of the inactivated whole-virion vaccine for teenagers and adults. The investigators will test the vaccine in particip...

Safety and Immunogencity of H7N9 Influenza Antigen With 2 Adjuvant Formulations in Healthy Adults in Brazil

The overall aim of this study is to evaluate the safety, immunogenicity and dose sparing effects of H7N9 influenza antigen formulated with 2 different adjuvants .

Co-Administration of AS03 Adjuvanted A/H7N9 IIV With IIV4

This is a randomized, un-blinded, Phase II study in males and non-pregnant females, who are in good health, 19 to 64 years of age. This study is designed to assess the safety, reactogenici...

Sanofi 2017 H7N9 With/Without AS03 in Adults/Elderly

This is a randomized, double-blinded, Phase II study in healthy males and non-pregnant females 19 years and older that is designed to assess the safety, reactogenicity, and immunogenicity ...

PubMed Articles [30 Associated PubMed Articles listed on BioPortfolio]

A neuraminidase activity-based microneutralization assay for evaluating antibody responses to influenza H5 and H7 vaccines.

Outbreaks of the highly pathogenic avian influenza H5N1 and H7N9 viruses have spurred an unprecedented research effort to develop antivirals and vaccines against influenza. Standardized methods for va...

Genetic characteristics of hemagglutinin and neuraminidase of avian influenza A (H7N9) virus in Guizhou province, 2014-2017.

To understand the molecular characteristics of hemagglutinin (HA) and neuraminidase (NA) as well as the disease risk of influenza virus A H7N9 in Guizhou province. RNAs were extracted and sequenced f...

Vaccination of poultry successfully eliminated human infection with H7N9 virus in China.

The H7N9 viruses that emerged in China in 2013 were nonpathogenic in chickens but mutated to a highly pathogenic form in early 2017 and caused severe disease outbreaks in chickens. The H7N9 influenza ...

Rapid evolving H7N9 avian influenza A viruses pose new challenge.

Rapid detection of multiple respiratory viruses based on microfluidic isothermal amplification and a real-time colorimetric method.

Respiratory viruses are major threats causing development of acute respiratory tract infections, which are common causes of illness and death throughout the world. Here, an integrated microsystem base...

In vitro characterization of baloxavir acid, a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit.

Cap-dependent endonuclease (CEN) resides in the PA subunit of the influenza virus and mediates the critical "cap-snatching" step of viral RNA transcription, which is considered to be a promising anti-...

Identification of two residues within the NS1 of H7N9 influenza A virus that critically affect the protein stability and function.

The emerging avian-origin H7N9 influenza A virus, which causes mild to lethal human respiratory disease, continues to circulate in China, posing a great threat to public health. Influenza NS1 protein ...

Hemagglutinin characteristics, changes in pathogenicity, and antigenic variation of highly pathogenic H7N9 avian influenza viruses in China.

A family cluster of two fatal cases infected with influenza A (H7N9) virus in Kunming China, 2017.

Two imported family cases (mother and daughter) of fatal H7N9 infection in Kunming, China were reported in 2017. Epidemiological investigation showed that the two family members had both been exposed ...

Did the Highly Pathogenic Avian Influenza A(H7N9) Viruses Emerged in China Raise Increased Threat to Public Health?

The low pathogenic avian influenza A(H7N9) viruses (LPAI) were first identified in 2013 and have continued to infect humans since then. It was reported in February 2017 that the LPAI H7N9 virus has ev...

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Medical and Biotech [MESH] Definitions

A subtype of INFLUENZA A VIRUS with the surface proteins hemagglutinin 7 and neuraminidase 9. This avian origin virus was first identified in humans in 2013.

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