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Paroxysmal supraventricular tachycardia (PSVT) - Biotech, Pharma and Life Science Channel

10:15 EST 17th November 2018 | BioPortfolio

Paroxysmal supraventricular tachycardia (PSVT) is episodes of rapid heart rate that start in a part of the heart above the ventricles. "Paroxysmal" means from time to time.

The heart will suddenly start racing, then stop or slow down abruptly.  Episodes can last for seconds, minutes, hours or (in rare cases) days. They may occur regularly, several times a day, or very infrequently, once or twice a year.  The heart rate may be as high as 250 beats per minute, but is usually between 140 and 180 (a normal heartbeat should be 60-100 beats per minute at rest).

SVT is caused by abnormal electrical impulses that start suddenly in the upper chambers of your heart (the atria). These impulses override your heart's natural rhythm.  It is often a short circuit in the electrical system of your heart that causes these spontaneous impulses. The short circuit causes an electrical signal to travel continuously around in a circle. Each time the signal completes the circuit, the impulse spreads out to the rest of your heart, forcing it to beat rapidly.  SVT attacks often happen for no obvious reason. However, they may be triggered by a change in posture, exertion, emotional upset, coffee or alcohol.

Source: http://www.nhs.uk/conditions/Supraventricular-tachycardia/Pages/Introduction.aspx

View research papers on diagnosiscauses and treatment.

PubMed Articles [271 Associated PubMed Articles listed on BioPortfolio]

A pyramid-like model for heartbeat classification from ECG recordings.

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A case of focal ventricular tachycardia with alternating endocardial and epicardial exits: utility of non-invasive mapping in predicting exits.

A Wide Complex Tachycardia in a Woman During Exercise: Did She Tread Into Dangerous Territory?

Assessment of left atrial remodeling in paroxysmal atrial fibrillation with speckle tracking echocardiography: a study with an electrophysiological mapping system.

This study aimed to evaluate left atrial (LA) remodeling and fibrosis in paroxysmal atrial fibrillation (AF) using speckle tracking echocardiography (STE) based on the findings with radiofrequency ca...

Virtual electrophysiological study as a tool for evaluating efficacy of MRI techniques in predicting adverse arrhythmic events in ischemic patients.

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Wide Complex Tachycardia and Syncope in a Middle-Aged Woman.

Supraventricular Arrhythmias: Clinical Framework and Common Scenarios for the Internist.

Supraventricular arrhythmias can cause uncomfortable symptoms for patients. Often, the first point of contact is in the primary care setting, and thus, it is imperative for the general internist to ha...

Sudden cardiac arrest in patients without overt heart disease: limited value of next generation sequencing.

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Catecholaminergic polymorphic ventricular tachycardia patients with multiple genetic variants in the PACES CPVT Registry.

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is often a life-threatening arrhythmia disorder with variable penetrance and expressivity. Little is known about the incidence or outcomes ...

Arrhythmia initiation in catecholaminergic polymorphic ventricular tachycardia type 1 depends on both heart rate and sympathetic stimulation.

Catecholaminergic polymorphic ventricular tachycardia type 1 (CPVT1) predisposes to ventricular tachyarrhythmias (VTs) during high heart rates due to physical or psychological stress. The essential ro...

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Radioablation for Ventricular Tachycardia: The Next Frontier

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Alexion’s Soliris successor in PNH unlikely to achieve price premium

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Loyola tests new catheter ablation system that can reach deeper into heart muscle

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New ablation treatment for ventricular tachycardia reaches deeper into heart muscle

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Companies [5 Associated Companies listed on BioPortfolio]

Alexion Pharmaceuticals Inc.

Alexion is a global biopharmaceutical company focused on developing and delivering life-transforming therapies for patients with devastating and rare disorders. Alexion developed ...

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Topera, Inc.

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Topera Medical

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Hybrid Therapy and Heart Team for Atrial Fibrillation

Atrial fibrillation (AF) is the most common cardiac arrhythmia with a prevalence ranging from 5% over 60 years old to 17% after 85 years old. Besides hemodynamical compromises and occurren...

The Benefit of Local Anesthesia at the Sternum in Patients With Coronary Surgery

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Trial to Evaluate the Efficacy and Safety of Substrate Ablation of Monomorphic Ventricular Tachycardia

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Lidocaine to Prevent Cough and Hemodynamic Changes in Tracheal Extubation

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Prospective Evaluation of Open Irrigated Ablation Catheters With High Resolution Mapping to Treat Paroxysmal Atrial Fibrillation

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Atrial Fibrillation Lifestyle Project

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CRyoAblation vs AntiaRrhythmic Drugs for Persistent Atrial Fibrillation Trial

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Medical and Biotech [MESH] Definitions

A generic expression for any tachycardia that originates above the BUNDLE OF HIS.

A rare form of supraventricular tachycardia caused by automatic, not reentrant, conduction initiated from sites at the atrioventricular junction, but not the ATRIOVENTRICULAR NODE. It usually occurs during myocardial infarction, after heart surgery, or in digitalis intoxication with a HEART RATE ranging from 140 to 250 beats per minute.

Abnormally rapid heartbeats with sudden onset and cessation.

An abnormally rapid ventricular rhythm usually in excess of 150 beats per minute. It is generated within the ventricle below the BUNDLE OF HIS, either as autonomic impulse formation or reentrant impulse conduction. Depending on the etiology, onset of ventricular tachycardia can be paroxysmal (sudden) or nonparoxysmal, its wide QRS complexes can be uniform or polymorphic, and the ventricular beating may be independent of the atrial beating (AV dissociation).

A condition characterized by the recurrence of HEMOGLOBINURIA caused by intravascular HEMOLYSIS. In cases occurring upon cold exposure (paroxysmal cold hemoglobinuria), usually after infections, there is a circulating antibody which is also a cold hemolysin. In cases occurring during or after sleep (paroxysmal nocturnal hemoglobinuria), the clonal hematopoietic stem cells exhibit a global deficiency of cell membrane proteins.

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