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UGenRA - Genitourinary cancer array - Biotech, Pharma and Life Science Channel

15:46 EST 23rd January 2019 | BioPortfolio

UGenRA is a CGI custom-designed oligonucleotide array designed to detect gains and losses of genomic material in endometrial, ovarian, and cervical cancers. Endometrial hyperplasia is a precursor lesion of endometriod endometrial carcinoma (EEC) and since about 50% of women with atypical hyperplasia also have concurrent EEC, it is important to identify those precursor lesions more likely to progress to and those with frank cancer. UGenRATM offers the opportunity to identify such specimens and potentially guide clinical management. Another potential application is to stratify those tumors likely to recur, permitting the identification of patients most likely to benefit from adjuvant therapy. Risk-stratification of stage III/IV ovarian cancer patients after cytoreductive surgery for front-line platinum taxane-based chemotherapy is a potential application for UGenRATM, and the design currently contains the sites of genomic gain/loss with such prognostic value. For any of the three cancers, genomic gain/loss associated with response to particular therapies can be assessed using UGenRATM, especially with the need of only small amounts of starting material and the ability to perform UGenRATM on FFPE specimens.

Source: http://cancergenetics.com/cgi-research/cgh-microarray/  UGenRA is a Registered Trademark of CGI

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