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Coronavirus - Biotech, Pharma and Life Science Channel

01:30 EST 17th November 2018 | BioPortfolio

Coronavirus were first identified in the 1960s, and were named after the crown-like projections on the surface of the virus. They cause respiratory infections in both humans and animals.

Coronaviruses are a large family of viruses that includes viruses that may cause a range of illnesses in humans, from the common cold to SARS. Viruses of this family also cause a number of animal diseases.

Novel coronavirus
This particular strain of coronavirus has not been previously identified in humans. There is very limited information on transmission, severity and clinical impact with only a small number of cases reported thus far.

From September 2012 to date, WHO has been informed of a global total of 38 laboratory confirmed cases of human infection with nCoV (Novel coronavirus) including 20 deaths.  For more inforamtion open http://www.who.int/csr/disease/coronavirus_infections/en/index.html

News Articles [3 Associated News Articles listed on BioPortfolio]

2018 POC Infectious Disease Testing Market: Reagent and Instrument Supplier Shares, Sales Segment Forecasts for 100 Tests, Emerging Technologies, Instrumentation Review, Competitive Landscape, Opportunities for Suppliers [Report Updated: 01011970] Prices

VPGMarketResearchrsquo;s new report provides comprehensive analysis of thenbsp; POC infections disease testing market, including its dynamics, size, growth, regulatory requirements, technological tren...

Cerus Announces Schedule of Presentations at the 2018 AABB Annual Meeting

Cerus Corporation (Nasdaq: CERS) announced today its schedule of key events and presentations at the 2018 AABB Annual Meeting which is taking place in Boston on October 13 through...

2018 France Microbiology Market Shares, Segmentation Forecasts, Competitive Landscape, Innovative Technologies, Latest Instrumentation, Opportunities for Suppliers [Report Updated: 01011970] Prices from USD $4750

Complete report $6,700. DataPack test volumes, sales forecasts, supplier shares $4,300. VPGMarketResearch .com presents a new strategic analysis of major business opportunities emerging in the infecti...

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Clinical Trials [15 Associated Clinical Trials listed on BioPortfolio]

Evaluate the Safety, Tolerability and Immunogenicity Study of GLS-5300 in Healthy Volunteers

The Middle East Respiratory Syndrome Coronavirus (MERS CoV), is a cause of severe and highly fatal lower respiratory tract infection, first identified in 2012. As of August 2018, there hav...

Safety, Tolerability and Immunogenicity of Vaccine Candidate MVA-MERS-S

The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is a potentially fatal disease with a reported lethality of up to 40% that is under tight epidemiologic control by the World Hea...

Identification of Host Factors of Norovirus Infections in Mini-Gut Model

The primary objective in this study is to establish a list of host cellular proteins that mediate norovirus infection. Norovirus is one of the most common pathogens attributed to diarrhea...

Yellow Fever Vaccine on Statin/ Non Statin Subjects

Since the 1st pandemic of the 21st century caused by SARS coronavirus, the world has experienced outbreaks of swine origin H1N1 influenza, Ebola and Zika viruses, which have all resulted i...

Assessment of Pharyngeal Carriage of Microorganisms Reponsible for Transmissible Acute Respiratory Infections in HAJJ Pilgrims.

The objective of this project is to study the prevalence of viruses and bacteria responsible for transmissible acute respiratory infections in the respiratory tract of pilgrims returning f...

MERS-CoV Infection tReated With A Combination of Lopinavir /Ritonavir and Interferon Beta-1b

This is a placebo-controlled clinical trial to assess the feasibility, efficacy and safety of a combination of lopinavir/ritonavir and Interferon beta-1b in hospitalized patients with MERS...

Safety, Tolerability, and Pharmacokinetics of SAB-301 in Healthy Adults

Background: Middle East Respiratory Syndrome (MERS) is a newly discovered contagious and sometimes fatal respiratory virus. People often get MERS through close contact with an infected pe...

Phase I, Open Label Dose Ranging Safety Study of GLS-5300 in Healthy Volunteers

The Middle East Respiratory Syndrome Coronavirus (MERS CoV), a virus related to Severe Acute respiratory syndrome coronavirus (SARS CoV), was first recognized as a cause of severe pulmonar...

Saudi Outcomes of ECMO-treated MERS-CoV Patients

A highly pathogenic human coronavirus causing respiratory disease emerged in Saudi Arabia in 2012. This viral infection termed Middle East respiratory syndrome coronavirus (MERS-CoV) is as...

Analysis of Human to Human Transmission of Middle East Respiratory Syndrom Coronavirus (MER-CoV)

This study aimed to analysis the characteristics of MERS transmission and the effect of our institutional personal protective equipment on the controlling the MERS at a tertiary Korean Hos...

PubMed Articles [66 Associated PubMed Articles listed on BioPortfolio]

Critically ill healthcare workers with the middle east respiratory syndrome (MERS): A multicenter study.

Middle East Respiratory Syndrome Coronavirus (MERS-CoV) leads to healthcare-associated transmission to patients and healthcare workers with potentially fatal outcomes.

Human Coronavirus in Hospitalized Children with Respiratory Tract Infections: A Nine-year-long, Population-based Study from Norway.

The burden of Human Coronavirus- (HCoV) associated respiratory tract infections (RTIs) in hospitalized children is poorly defined. We studied the occurrence and hospitalization rates of HCoV over nine...

Functional analysis of potential cleavage sites in the MERS-coronavirus spike protein.

The Middle East respiratory syndrome-related coronavirus (MERS-CoV) can cause severe disease and has pandemic potential. Therefore, development of antiviral strategies is an important task. The activa...

Identification of Pantropic Canine Coronavirus in a Wolf ( Canis lupus italicus) in Italy.

We report a case in an Italian wolf ( Canis lupus italicus) of pantropic canine coronavirus infection, which has previously been detected only in dogs. The wolf was coinfected by canine parvovirus typ...

Protease inhibitors broadly effective against feline, ferret and mink coronaviruses.

Ferret and mink coronaviruses typically cause catarrhal diarrhea in ferrets and minks, respectively. In recent years, however, systemic fatal coronavirus infection has emerged in ferrets, which resemb...

Resistance to coronavirus infection in amino peptidase N-deficient pigs.

The alphacoronaviruses, transmissible gastroenteritis virus (TGEV) and Porcine epidemic diarrhea virus (PEDV) are sources of high morbidity and mortality in neonatal pigs, a consequence of dehydration...

Serologic Survey of Selected Viral Pathogens in Free-Ranging Eurasian Brown Bears ( Ursus arctos arctos) from Slovakia.

We tested sera of 24 free-ranging European brown bears ( Ursus arctos) from six regions of Slovakia for antibodies to 10 viral agents. We tested sera by an indirect fluorescence antibody test for anti...

Clinical implication of radiographic scores in acute Middle East respiratory syndrome coronavirus pneumonia: Report from a single tertiary-referral center of South Korea.

The aim of this study is to determine the earliest cutoff of radiographic score as a potential prognostic indicator of fatal outcomes in patients with acute Middle East respiratory syndrome coronaviru...

Elevated Human Dipeptidyl Peptidase 4 Expression Reduces the Susceptibility of hDPP4 Transgenic Mice to Middle East Respiratory Syndrome Coronavirus Infection and Disease.

The ongoing Middle East Respiratory Syndrome (MERS) Coronavirus (CoV) infections pose threats to public health worldwide, making an understanding of MERS pathogenesis and development of effective medi...

The papain-like protease determines a virulence trait that varies among members of the SARS-coronavirus species.

SARS-coronavirus (CoV) is a zoonotic agent derived from rhinolophid bats, in which a plethora of SARS-related, conspecific viral lineages exist. Whereas the variability of virulence among reservoir-bo...

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Medical and Biotech [MESH] Definitions

The type species of BETACORONAVIRUS genus causing gastroenteritis respiratory diseases in mammals. Previously separate species HUMAN CORONAVIRUS OC43; BOVINE CORONAVIRUS; Human enteric coronavirus; Equine coronavirus; and Porcine hemagglutinating encephalomyelitis virus merged into this species on the basis of similar genome nucleotide sequence and genome organization.

A species of CORONAVIRUS causing enteritis in turkeys and pullets.

A species of CORONAVIRUS infecting neonatal calves, presenting as acute diarrhea, and frequently leading to death.

A species of CORONAVIRUS infecting dogs. Onset of symptoms is usually sudden and includes vomiting, diarrhea, and dehydration.

A species in the genus CORONAVIRUS causing the common cold and possibly nervous system infections in humans. It contains hemagglutinin-esterase.

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