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Coronavirus - Biotech, Pharma and Life Science Channel

06:29 EDT 20th September 2018 | BioPortfolio

Coronavirus were first identified in the 1960s, and were named after the crown-like projections on the surface of the virus. They cause respiratory infections in both humans and animals.

Coronaviruses are a large family of viruses that includes viruses that may cause a range of illnesses in humans, from the common cold to SARS. Viruses of this family also cause a number of animal diseases.

Novel coronavirus
This particular strain of coronavirus has not been previously identified in humans. There is very limited information on transmission, severity and clinical impact with only a small number of cases reported thus far.

From September 2012 to date, WHO has been informed of a global total of 38 laboratory confirmed cases of human infection with nCoV (Novel coronavirus) including 20 deaths.  For more inforamtion open http://www.who.int/csr/disease/coronavirus_infections/en/index.html

News Articles [4 Associated News Articles listed on BioPortfolio]

Enzymatica AB: Continued growth during the first quarter

                                                                                                       I...

Severe Acute Respiratory Syndrome SARS Coronavirus Infection Market Insight, Epidemiology and Market Forecast 2027 [Report Updated: 14022018] Prices from USD $6250

DelveInsight's "Severe Acute Respiratory Syndrome SARS Coronavirus Infection Market Insight, Epidemiology and Market Forecast 2027" report provides a detailed analysis of the Severe Acute Respirato...

Severe Acute Respiratory Syndrome SARS Coronavirus Infection Pipeline Insight, 2018 [Report Updated: 14022018] Prices from USD $1250

"Severe Acute Respiratory Syndrome SARS Coronavirus Infection Pipeline Insight, 2018 report by DelveInsight offers comprehensive Insight of the pipeline under development therapeutics scenario and gr...

Severe Acute Respiratory Syndrome SARS Coronavirus Infection Epidemiology Forecast to 2027 [Report Updated: 14022018] Prices from USD $3250

DelveInsight's "Severe Acute Respiratory Syndrome SARS Coronavirus Infection Epidemiology Forecast, 2027 report provides a comprehensive analysis of the Severe Acute Respiratory Syndrome SARS Coron...

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Clinical Trials [14 Associated Clinical Trials listed on BioPortfolio]

Safety, Tolerability and Immunogenicity of Vaccine Candidate MVA-MERS-S

The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is a potentially fatal disease with a reported lethality of up to 40% that is under tight epidemiologic control by the World Hea...

Identification of Host Factors of Norovirus Infections in Mini-Gut Model

The primary objective in this study is to establish a list of host cellular proteins that mediate norovirus infection. Norovirus is one of the most common pathogens attributed to diarrhea...

Yellow Fever Vaccine on Statin/ Non Statin Subjects

Since the 1st pandemic of the 21st century caused by SARS coronavirus, the world has experienced outbreaks of swine origin H1N1 influenza, Ebola and Zika viruses, which have all resulted i...

Assessment of Pharyngeal Carriage of Microorganisms Reponsible for Transmissible Acute Respiratory Infections in HAJJ Pilgrims.

The objective of this project is to study the prevalence of viruses and bacteria responsible for transmissible acute respiratory infections in the respiratory tract of pilgrims returning f...

MERS-CoV Infection tReated With A Combination of Lopinavir /Ritonavir and Interferon Beta-1b

This is a placebo-controlled clinical trial to assess the feasibility, efficacy and safety of a combination of lopinavir/ritonavir and Interferon beta-1b in hospitalized patients with MERS...

Safety, Tolerability, and Pharmacokinetics of SAB-301 in Healthy Adults

Background: Middle East Respiratory Syndrome (MERS) is a newly discovered contagious and sometimes fatal respiratory virus. People often get MERS through close contact with an infected pe...

Phase I, Open Label Dose Ranging Safety Study of GLS-5300 in Healthy Volunteers

The Middle East Respiratory Syndrome Coronavirus (MERS CoV), a virus related to Severe Acute respiratory syndrome coronavirus (SARS CoV), was first recognized as a cause of severe pulmonar...

Saudi Outcomes of ECMO-treated MERS-CoV Patients

A highly pathogenic human coronavirus causing respiratory disease emerged in Saudi Arabia in 2012. This viral infection termed Middle East respiratory syndrome coronavirus (MERS-CoV) is as...

Analysis of Human to Human Transmission of Middle East Respiratory Syndrom Coronavirus (MER-CoV)

This study aimed to analysis the characteristics of MERS transmission and the effect of our institutional personal protective equipment on the controlling the MERS at a tertiary Korean Hos...

Seroprevalence of MERS-CoV IgG in Healthcare Workers

The investigators aim to do serosurvey of healthcare-personnel who had participated in treatment of confirmed patients of Middle-East respiratory syndrome. The investigators collected the ...

PubMed Articles [68 Associated PubMed Articles listed on BioPortfolio]

MOLECULAR IDENTIFICATION OF AVIAN VIRUSES IN NEOTROPIC CORMORANTS ( PHALACROCORAX BRASILIANUS) IN CHILE.

We identified two RNA (paramyxovirus and coronavirus) and two DNA (adenovirus and herpesvirus) viruses in a common aquatic bird, the Neotropic Cormorant ( Phalacrocorax brasilianus), and determined th...

Lack of seasonal variation of Middle East respiratory syndrome coronavirus (MERS-CoV).

Case Report of Transmissible Gastroenteritis Coronavirus Infection Associated with Small Intestine and Brain Lesions in Piglets.

This case study report describes a transmissible gastroenteritis coronavirus (TGEV) infection presented in a commercial pig herd. The clinical signs of infection appeared in newborn piglets, including...

De Novo Design of α-Helical Lipopeptides Targeting Viral Fusion Proteins: A Promising Strategy for Relatively Broad-spectrum Antiviral Drug Discovery.

Class I enveloped viruses share similarities in their apparent use of a hexameric coiled-coil assembly to drive the merging of virus and host cell membranes. Inhibition of coiled coil-mediated interac...

Description and initial characterization of metatranscriptomic nidovirus-like genomes from the proposed new family Abyssoviridae, and from a sister group to the Coronavirinae, the proposed genus Alphaletovirus.

Transcriptomics has the potential to discover new RNA virus genomes by sequencing total intracellular RNA pools. In this study, we have searched publicly available transcriptomes for sequences similar...

Novel coronavirus-like particles targeting cells lining the respiratory tract.

Virus like particles (VLPs) produced by the expression of viral structural proteins can serve as versatile nanovectors or potential vaccine candidates. In this study we describe for the first time the...

Three Main Inducers of Alphacoronavirus Infection of Enterocytes: Sialic Acid, Proteases, and Low pH.

Transmissible gastroenteritis virus (TGEV) and porcine epidemic diarrhea virus (PEDV) are similar coronaviruses, causing diseases characterized by vomiting, diarrhea, and death from severe dehydration...

Retrospective detection and phylogenetic analysis of swine acute diarrhea syndrome coronavirus in pigs in southern China.

Swine acute diarrhea syndrome coronavirus (SADS-CoV), a novel coronavirus, was first discovered in southern China in January 2017 and caused a large scale outbreak of fatal diarrheal disease in piglet...

Crystal structure of the post-fusion core of the Human coronavirus 229E spike protein at 1.86 Å resolution.

Human coronavirus 229E (HCoV-229E) usually causes mild upper respiratory infections in heathy adults, but may lead to severe complications or mortality in individuals with weakened immune systems. Vir...

New clinical and seasonal evidence of infections by Human Parainfluenzavirus.

Human Parainfluenzaviruses (PIVs) account for a significant proportion of viral acute respiratory infections (ARIs) in children, and are also associated with morbidity and mortality in adults, includi...

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Medical and Biotech [MESH] Definitions

The type species of BETACORONAVIRUS genus causing gastroenteritis respiratory diseases in mammals. Previously separate species HUMAN CORONAVIRUS OC43; BOVINE CORONAVIRUS; Human enteric coronavirus; Equine coronavirus; and Porcine hemagglutinating encephalomyelitis virus merged into this species on the basis of similar genome nucleotide sequence and genome organization.

A species of CORONAVIRUS causing enteritis in turkeys and pullets.

A species of CORONAVIRUS infecting neonatal calves, presenting as acute diarrhea, and frequently leading to death.

A species of CORONAVIRUS infecting dogs. Onset of symptoms is usually sudden and includes vomiting, diarrhea, and dehydration.

A species in the genus CORONAVIRUS causing the common cold and possibly nervous system infections in humans. It contains hemagglutinin-esterase.

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