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Cutaneous or mucosal infections - Biotech, Pharma and Life Science Channel

05:38 EDT 24th October 2017 | BioPortfolio

PubMed Articles [4634 Associated PubMed Articles listed on BioPortfolio]

Testing Experimental Therapies in a Guinea Pig Model for Hemorrhagic Fever.

Hemorrhagic fever viruses are among the deadliest pathogens known to humans, and often, licensed medical countermeasures are unavailable to prevent or treat infections. Guinea pigs are a commonly used...

Identification of Trypanosomatids by detecting Single Nucleotide Fingerprints using DNA analysis by dynamic chemistry with MALDI-ToF.

Protozoan parasites of the Trypanosomatidae family can cause devastating diseases in humans and animals, such as Human African Trypanosomiasis or Sleeping Sickness, Chagas disease and Leishmaniasis. C...

Procoagulant activity during viral infections.

The abundance of evidence suggest that inflammation of immune and non-immune cells may lead to an imbalance of the pro- and anti-coagulant state during viral infections. During systemic infections, th...

Metal- and metalloid-containing drugs for the treatment of trypanosomatid diseases.

The trypanosomatid-induced diseases are considered as neglected, because the countries where they kill people are not important markets for western big pharmaceutical companies. However, recently some...

Gut microbiota - architects of small intestinal capillaries.

The commensal gut microbiota is an environmental factor that exerts manifold effects on host physiology. One obvious trait is the impact of this densely colonized ecosystem on small intestinal mucosal...

Molecular mechanisms of Chlamydia trachomatis resistance to antimicrobial drugs.

Chlamydia trachomatis (C. trachomatis) is a leading cause of bacterial sexually transmitted infections in developed and undeveloped countries, and therefore a global public health issue. In an era of ...

Role of fibroblast growth factor receptor-2 splicing in normal and cancer cells.

Types 1-4 of fibroblast growth factor receptors (FGFR) are all expressed in various cancers. Because of its prominent role in carcinogenesis and cancer progression, FGFR-2, is being considered as a no...

Histone deacetylase: A potential therapeutic target for ovarian dysfunction.

Post-partum uterine disorders and reproductive tract infections cause ovarian dysfunction and infertility. Histone deacetylases (HDACs) prevent the relaxation of chromatin, and positively or negativel...

Tick-host-pathogen systems immunobiology: an interactive trio.

Significant new insights are being made into tick modulation of host immune defenses and the implications of those host defense changes on tick-borne pathogen transmission and establishment of infecti...

RecA: a universal drug target in pathogenic bacteria.

The spread of bacterial infectious diseases due to the development of resistance to antibiotic drugs in pathogenic bacteria is an emerging global concern. Therefore, the efficacious management and pre...

News Articles [1669 Associated News Articles listed on BioPortfolio]

Study finds lung cancer driver ALK-fusion in mucosal melanoma

Melanomas caused by sun exposure have been matched with targeted treatments and immunotherapies, in many cases dramatically extending patients' lives. However, there are other kinds of melanoma not re...

Paragon Foods Recalls 1.7 Ounce Bagged Broccoli Florets Because of Possible Health Risk

Paragon Wholesale Foods Corp., of Warrendale, PA, is recalling several lots of 1.7 ounce Broccoli Florets in response to a nationwide recall by one of its suppliers, Mann Packing (Salinas, CA) because...

Arsanis Eyes IPO to Support Clinical Testing of Pneumonia Drug

Arsanis is joining the IPO queue, filing for a stock offering that would raise cash to support a drug that combines two monoclonal antibodies with the goal of preventing pneumonia infections. The fili...

Curetis initiates U.S. FDA study for Unyvero Invasive Joint Infections Cartridge

Curetis / Curetis initiates U.S. FDA study for Unyvero Invasive Joint Infections Cartridge . Processed and transmitted by Nasdaq Corporate Solutions. The issuer is solely responsible for the content o...

Enanta’s Announces Positive Early-Stage Results for its Lead FXR Agonist

WATERTOWN, Mass.–(BUSINESS WIRE)–Enanta Pharmaceuticals, Inc. (NASDAQ:ENTA), a chemistry-driven biotechnology company dedicated to creating small molecule drugs for viral infections and li...

Rutgers researchers to explore ways for tackling emerging fungal infections

In recent years, hospitals nationwide have been reporting an increase in life-threatening illnesses resulting from a deadly fungal infection caused by the yeast Candida auris that can enter the bloods...

Unintended Consequences: Steps to Fight Sepsis Increase C. diff

A hospital effort to rapidly identify potential sepsis cases and initiate antibiotic treatment led to an unintended consequence: an increase in Clostridium difficile infections.

Appili Therapeutics Raises $3M to Advance Its Anti-Infective Pipeline

Appili Therapeutics Inc. (the “Company” or “Appili”), an anti-infective drug development company, announced today it raised $3,062,000 in a private placement financing, br...

Public Health England sounds warning against overuse of antibiotics

Public Health England (PHE) has unveiled the findings from its English surveillance programme for antimicrobial utilisation and resistance report, suggesting that resistance is rising and antibiotics ...

Global Veterinary Vaccine Market Data Survey Report 2025 [Report Updated: 19102017] Prices from USD $1500

SummaryVaccines are products designed to trigger protective immune responses and prepare the immune system to fight future infections from diseasecausing agents. Vaccines stimulate the immune system's...

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Companies [108 Associated Companies listed on BioPortfolio]

Peptilogics

Peptilogics is an early-stage biotechnology company developing a new class of antibiotics with a novel mechanism of action derived from their eCAP (engineered cationic antibiotic ...

HCA Healthcare, Inc.

Nashville-based HCA Healthcare is one of the nation's leading providers of healthcare services, operating 172 locally managed hospitals and 119 freestanding surgery centers in 20 ...

Symbiomix Therapeutics, LLC

Symbiomix (sim-bye-OH-mix) is a biopharmaceutical company bringing innovative medicines to market for prevalent gynecological infections that can have serious health consequences....

Osprey Medical Inc.

Osprey Medical's core technologies originated from research conducted by Dr David Kaye at Melbourne’s Baker IDI Heart and Diabetes Institute. Osprey is focused on improving p...

HCA Healthcare

Nashville-based HCA Healthcare is one of the nation's leading providers of healthcare services, operating 174 locally managed hospitals and 119 freestanding surgery centers in 20 ...

Ralexar Therapeutics, Inc.

Ralexar Therapeutics, Inc. is a privately-held specialty pharmaceutical company founded in January 2014 and based in Malvern, Pennsylvania. The company is developing topical and s...

PAVmed Inc.

PAVmed Inc. (Nasdaq: PAVM, PAVMW) is a highly differentiated, multi-product medical device company employing a unique business model designed to advance products from concept to c...

Appili Therapeutics Inc.

Appili is dedicated to identifying, acquiring and advancing novel therapeutics for infectious disease. The company has two anti-infective programs, ATI-1501 and ATI-1503, in its p...

Affinivax, Inc.

Affinivax is advancing a next generation vaccine technology platform to enable the development of vaccines that provide the highest level of protection against challenging infecti...

Discuva

Discuva aims to revolutionise the treatment of disease caused by bacterial infection by discovering and developing new antibiotics against highly drug-resistant pathogens. The com...

Clinical Trials [3137 Associated Clinical Trials listed on BioPortfolio]

Open and Exploratory Trial to Investigate the Pharmacokinetic of Ceftobiprole Medocaril in Patients With CSF Device

Ceftobiprole is a very active new cephalosporin on staphylococci resistant to methicillin (SEMR: Staphylococcus epidermidis Resistant to Meticillin, SAMR: Staphylococcus aureus Resistant t...

SaniVac Trial - Sanitation and Oral Rotavirus Vaccine Performance

This is a controlled cohort study to assess the effect of improved sanitation on oral rotavirus vaccine performance in low-income urban neighbourhoods of Maputo, Mozambique. The specific h...

Pyridostigmine as Immunomodulator in People Living With HIV

Human immunodeficiency virus (HIV) infection is a public health problem with enormous personal, and social losses. According to the National Mexican HIV/AIDS survey, more than 235,000 new ...

FINDpath: Fast I(n)Dentification of PATHogens

Sepsis is the body-wide response to infection. People who develop sepsis have an increased risk of dying. One of the greatest challenges in sepsis is determining what is the pathogen (bact...

Epidemiology and Clinical Characteristics of Non-Tuberculous Mycobacteria Infections in Cystic Fibrosis Patients.

An increase in the prevalence of infections due to non-tuberculous mycobacteria (NTM) is observed in many countries and recent data suggest the circulation of dominant clones with a possib...

Neoadjuvant Treatment Associated With Maintenance Therapy by Anti-PD1 Immunotherapy in Patients With Resectable Head and Neck Mucosal Melanoma

The main objective will be to estimate the disease free survival (DFS) of patients with resectable head and neck mucosal melanomas treated by neo-adjuvant anti-PD1 followed by surgery, rad...

Intra-lesional Nivolumab Therapy for Limited Cutaneous Kaposi Sarcoma

There is no clear treatment for patients with limited cutaneous Kaposi sarcoma (KS). Radiation and injection of vinblastine both have side effects that may not be acceptable. Nivolumab has...

Assessing the Impact of an Educational HIV Prevention Intervention in Zambia

In Zambia, 13% of the 15 to 49 year old population lives with HIV. The highest number of new HIV infections is among young people. To counter the spread of the disease, developmental and g...

Using mHealth Technology to Identify and Refer Surgical Site Infections in Rwanda

The present study aims to examine whether or not the use of mobile Health (mHealth) by community health workers (CHWs) can improve the identification of surgical site infection (SSI) and a...

Adherence to Oral Antibiotics In Patients With Osteoarticular Infections

Bone and joint infection (BJI) are bacterial infections that can occur after surgery (nosocomial infections) or de novo. They constitute a public health problem in Western Countries . Thes...

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Medical and Biotech [MESH] Definitions

A genus of DNA viruses in the family PAPILLOMAVIRIDAE, causing cutaneous or mucosal papillomas in cattle.

A genus of DNA viruses in the family PAPILLOMAVIRIDAE, causing cutaneous and mucosal lesions in rabbits. COTTONTAIL RABBIT PAPILLOMAVIRUS is the type species.

A genus of DNA viruses in the family papillomaviridae, causing mucosal and cutaneous lesions in cats and dogs. Canine oral papillomavirus is the type species.

Fungal infections caused by TRICHOSPORON that may become systemic especially in an IMMUNOCOMPROMISED HOST. Clinical manifestations range from superficial cutaneous infections to systemic lesions in multiple organs.

A subset of T-lymphocytes that are present in large numbers at MUCOUS MEMBRANES and respond to INFECTIONS. They express a conserved invariant T-CELL RECEPTOR ALPHA-CHAIN that enables them to respond to infections by sensing RIBOFLAVIN metabolites of pathogens.

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