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Diseasemodifying drugs - Biotech, Pharma and Life Science Channel

03:40 EST 12th December 2017 | BioPortfolio

PubMed Articles [4319 Associated PubMed Articles listed on BioPortfolio]

Thoracic Surgery in Patients with AIDS.

The picture of human immunodeficiency virus (HIV)-infected patients has changed dramatically since the original description in 1981. The introduction of antiretroviral drugs in 1987 and combination an...

Trends in Financial Access to Prescription Drugs Among Cancer Survivors.

Little is known about the competing effects of increasing prescription drug costs and expansions in insurance coverage on prescription drug access and whether trends vary for adults with and without a...

Techniques Used for Functional Characterization of Polyamine Transporters.

Transport systems are key processes in every living organism: they allow the entry of all essential nutrients into the cell and its compartments and regulate the intracellular concentrations of metabo...

Influence of the alkylating function of aldo-Ifosfamide on the anti-tumor activity.

The present work investigates the influence of different DNA damages caused by different isophosphoramide mustards on the 3-hydroxypropanal-assisted apoptotic antitumor activity of oxazaphosphorine cy...

The N-butyl-N-4-hydroxybutyl Nitrosamine Mouse Urinary Bladder Cancer Model.

Urinary bladder cancer (UBC) is a common and complex malignancy, with a multifactorial etiology, like environmental factors, such as cigarette smoking, occupational exposure, and genetic factors.UBC e...

Visualization and Quantitative Measurement of Drug-Induced Platinum Adducts in the Nuclear DNA of Individual Cells by an Immuno-Cytological Assay.

Immunocytological staining with adduct-specific antibodies allows the visualization and measurement of structurally defined types of DNA damage in the nuclei of individual cells. Here we describe an i...

Optimization of Multi-Omic Genome-Scale Models: Methodologies, Hands-on Tutorial, and Perspectives.

Genome-scale metabolic models are valuable tools for assessing the metabolic potential of living organisms. Being downstream of gene expression, metabolism is increasingly being used as an indicator o...

Nerve Growth Factor-Induced Angiogenesis: 1. Endothelial Cell Tube Formation Assay.

Nerve growth factor (NGF) is a neurotrophin promoting survival, proliferation, differentiation, and neuroprotection in the embryonal and adult nervous system. NGF also induces angiogenic effects in th...

Active Induction of Experimental Autoimmune Encephalomyelitis in C57BL/6 Mice.

The protocol in this chapter presents a method to actively induce experimental autoimmune encephalomyelitis (EAE), one of the most widely used animal models to study efficacy of potential drugs for tr...

Synthesis of Biocompatible Titanate Nanofibers for Effective Delivery of Neuroprotective Agents.

Nanoscience provides us with new opportunities to develop nanotechnologies for treating, in particular, central nervous system disorders such as Alzheimer disease and multiple sclerosis. From a method...

News Articles [4226 Associated News Articles listed on BioPortfolio]

Hepatitis DrugsIndia Market Status and Trend Report 20132023 [Report Updated: 23112017] Prices from USD $2980

Report SummaryHepatitis DrugsIndia Market Status and Trend Report 20132023 offers a comprehensive analysis on Hepatitis Drugs industry, standing on the readers' perspective, delivering detailed market...

Liver Diseases Therapeutics DrugsAsia Pacific Market Status and Trend Report 20132023 [Report Updated: 23112017] Prices from USD $3480

Report SummaryLiver Diseases Therapeutics DrugsAsia Pacific Market Status and Trend Report 20132023 offers a comprehensive analysis on Liver Diseases Therapeutics Drugs industry, standing on the reade...

Amgen's Kyprolis improves overall survival in blood cancer patients

(Reuters) - Amgen Inc said on Monday new data from a late-stage trial testing Kyprolis in combination with two other drugs showed improved overall survival rate in patients with blood cancer.

Good Pharma Scorecard judges clinical trial transparency

Bioethics International announced the second publication of its Good Pharma Scorecard (GPS), an annual index ranking large pharmaceutical companies and new drugs on their clinical trial transparency, ...

Bluebird Bio Stock Soars After Company Details Promising Cancer Treatment

Click to view a price quote on BLUE. Click to research the Drugs industry.

Some prescription drugs are cheaper without insurance

Body:  Consumers are increasingly paying more for drugs through health insurance than they would if they found the best deal on their own, according to an article published jointly by The New Yor...

Osteoarthritis Pain DrugsEurope Market Status and Trend Report 20132023 [Report Updated: 23112017] Prices from USD $3480

Report SummaryOsteoarthritis Pain DrugsEurope Market Status and Trend Report 20132023 offers a comprehensive analysis on Osteoarthritis Pain Drugs industry, standing on the readers' perspective, deliv...

Five Questions for the Senate Hearing on Prescription Drugs

On Tuesday, the Senate Committee on Health, Education, Labor, and Pensions will hold its third ...

Turning pathogens against each other to prevent drug resistance

Limiting a much-needed resource could pit pathogens against one another and prevent the emergence of drug resistance. New research demonstrates that harnessing competition among pathogens inside a pat...

Serious infection rate low in patients with RA treated with biologic DMARDs, denosumab

Patients with rheumatoid arthritis who take biologic disease-modifying antirheumatic drugs, including those with concurrent denosumab use, demonstrated a low occurrence of serious and opportunistic in...

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Companies [284 Associated Companies listed on BioPortfolio]

ImmunoMolecular Therapeutics

IM Therapeutics is developing personalized immuno-therapeutic drugs for autoimmune diseases based on the genetic risk attributed by human leukocyte antigen genes. The lead candida...

Kubota Pharmaceutical Holdings Co., Ltd.

Kubota Pharmaceutical Holdings Co., Ltd. (Tokyo 4596) is committed to translating innovation into a diverse portfolio of drugs and devices to preserve and restore vision for milli...

Italfarmaco

Italfarmaco is a specialty pharmaceutical company engaged in the discovery, development, manufacturing and marketing of branded prescription and nonprescription products in more t...

Neuronax SAS

NEURONAX is a privately-held biopharmaceutical company focusing on the development and discovery of therapeutic approaches to treat central nervous system disorders. Combining an expertise in the dev...

DisperSol Technologies LLC

DisperSol is an innovator in the formulation development and manufacture of pharmaceutical drugs. DisperSol’s KinetiSol® technology has dramatically improved the effective...

Lin BioScience, Inc.

Lin BioScience, Inc. is a drug development company specializing in innovative therapies for diseases with unmet medical needs. Lin BioScience's diverse pipeline consists of first-...

Vidac Pharma

Vidac Pharma is an innovative clinical-stage oncology- and dermatology-focused pharmaceutical company, developing novel drugs to help people suffering from a range of diseases. Vi...

LEO Pharma

Founded more than 100 years ago, LEO Pharma is an independent, research-based specialty pharmaceutical company committed to the discovery and development of novel drugs for patien...

NanOlogy LLC

NanOlogy, LLC (www.nanology.us) is a company formed by DFB Pharmaceuticals, LLC of Fort Worth, TX, CritiTech, Inc. of Lawrence, KS, and US Biotest, Inc. of San Luis Obispo,...

Phoenix Biotechnology, Inc.

Phoenix Biotechnology, Inc., a San Antonio, Texas based biotechnology company, was incorporated in Texas in 2003 to develop promising agents with minimal or no side effects for ta...

Clinical Trials [1183 Associated Clinical Trials listed on BioPortfolio]

Removal of Beta Blocker Drugs by Hemodialysis

Eight maintenance hemodialysis patients are given one of four beta blocker drugs (atenolol, bisoprolol, carvedilol, metoprolol) three hours prior to a hemodialysis session. Blood samples a...

Evaluating Treatment as Prevention Among People Who Inject Drugs in Dundee for HCV

The aim of this study is to conduct an evaluation of hepatitis C treatments in NHS Tayside in order to empirically test the "treatment as prevention" models. This will be done by analysing...

Tazemetostat in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Endometrial Cancer

This phase II trial studies how well tazemetostat works in treating patients with ovarian, primary peritoneal, or endometrial cancer that has come back. Drugs used in chemotherapy, such as...

A Study to Evaluate the Effect of 2 Drugs on the Pharmacokinetics of BMS-986205 in Healthy Subjects

Assess the effects of itraconazole and rifampin on the pharmacokinetics, safety, and tolerability of BMS-986205.

Evaluation of Adherence to Clinical Treatment of Glaucoma

Evaluation of adherence to clinical treatment of glaucoma in patients of a Reference Ophthalmological Hospital in Goiânia using Morisky Adhesion scale as a validated questionary.

Balance and Anti-Epileptic Drugs

Patients with epilepsy exercise less than the general population. A barrier to exercise may be the effect of antiepileptic drugs on balance and reaction time. This proposal endeavors to st...

Platelet Function With Various Storage Techniques

Platelet function will be tested in individuals on antiplatelet medications to determine the optimal storage methodology.

Remifemin Preventing the Climacteric Symptoms in Breast Cancer

LHRH-a is an important hormone treatment in breast cancer especially in high-risk hormone receptor-positive patients or hormone receptor-negative but needing ovarian function protecting. T...

Therapeutic Drug Monitoring of Anti-infectious Drugs in Intensive Care Unit

This research targets four anti-infectives commonly prescribed in intensive care: ceftazidime, cefepime, cefotaxime and meropenem, used for severe infections For patient hospitalized in in...

Study of Personalized Melphalan Dosing in the Setting of Autologous Transplant

This randomized phase II trial studies the side effects and how well melphalan hydrochloride works in treating patients with multiple myeloma that has come back or does not respond to trea...

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Medical and Biotech [MESH] Definitions

Drugs used by veterinarians in the treatment of animal diseases. The veterinarian's pharmacological armamentarium is the counterpart of drugs treating human diseases, with dosage and administration adjusted to the size, weight, disease, and idiosyncrasies of the species. In the United States most drugs are subject to federal regulations with special reference to the safety of drugs and residues in edible animal products.

Drugs which have received FDA approval for human testing but have yet to be approved for commercial marketing. This includes drugs used for treatment while they still are undergoing clinical trials (Treatment IND). The main heading includes drugs under investigation in foreign countries.

The use of multiple drugs administered to the same patient, most commonly seen in elderly patients. It includes also the administration of excessive medication. Since in the United States most drugs are dispensed as single-agent formulations, polypharmacy, though using many drugs administered to the same patient, must be differentiated from DRUG COMBINATIONS, single preparations containing two or more drugs as a fixed dose, and from DRUG THERAPY, COMBINATION, two or more drugs administered separately for a combined effect. (From Segen, Dictionary of Modern Medicine, 1992)

Drugs that mimic the effects of parasympathetic nervous system activity. Included here are drugs that directly stimulate muscarinic receptors and drugs that potentiate cholinergic activity, usually by slowing the breakdown of acetylcholine (CHOLINESTERASE INHIBITORS). Drugs that stimulate both sympathetic and parasympathetic postganglionic neurons (GANGLIONIC STIMULANTS) are not included here.

Drugs used to specifically facilitate learning or memory, particularly to prevent the cognitive deficits associated with dementias. These drugs act by a variety of mechanisms. While no potent nootropic drugs have yet been accepted for general use, several are being actively investigated.

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