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Dysfunctional Uterine Bleeding DUB - Biotech, Pharma and Life Science Channel

01:59 EDT 18th June 2018 | BioPortfolio

PubMed Articles [1669 Associated PubMed Articles listed on BioPortfolio]

The safety and efficacy of non-vitamin K antagonist oral anticoagulants in atrial fibrillation in the elderly.

Atrial fibrillation (AF) is the most common arrhythmia and its prevalence increases with age. Age also increases the risk of thromboembolism related to AF. As a result, elderly patients are at increas...

Characterizing the HeartMate II Left Ventricular Assist Device Outflow Using Particle Image Velocimetry.

Ventricular assist devices (VADs) are implanted in patients with a diseased ventricle to maintain peripheral perfusion as a bridge-to-transplant or as destination therapy. However, some patients with ...

Dysfunctional Autism Risk Genes Cause Circuit-Specific Connectivity Deficits With Distinct Developmental Trajectories.

Autism spectrum disorders (ASD) are a set of complex neurodevelopmental disorders for which there is currently no targeted therapeutic approach. It is thought that alterations of genes regulating migr...

Acquired von Willebrand syndrome in congenital heart disease surgery: results from an observational case-series.

Cardiac surgery of the newborn and infant with complex congenital heart disease (CHD) is associated with a high rate of intraoperative bleeding complications. CHD-related anatomic features such as val...

Invited Commentary on "CT for Evaluation of Acute Gastrointestinal Bleeding".

Intraoperative and postoperative complications of partial maxillectomy for the treatment of oral tumors in dogs.

OBJECTIVE To characterize and identify factors associated with intraoperative and postoperative complications of maxillectomy in dogs with oral tumors. DESIGN Retrospective cohort study. ANIMALS 193 d...

YAP is essential for Treg mediated suppression of anti-tumor immunity.

Regulatory T cells (Tregs) are critical for maintaining self-tolerance and immune homeostasis, but their suppressive function can impede effective anti-tumor immune responses. Foxp3 is a transcription...

Bisphenol A exposure during early pregnancy impairs uterine spiral artery remodeling and provokes intrauterine growth restriction in mice.

Endocrine disrupting chemicals are long suspected to impair reproductive health. Bisphenol A (BPA) has estrogenic activity and therefore the capacity of interfering with endocrine pathways. No studies...

Prophylactic bypassing agent use before and during immune tolerance induction in patients with haemophilia A and inhibitors to FVIII.

The development of high-titre inhibitory antibodies (inhibitors) against factor VIII (FVIII) remains a challenge in the management of patients with haemophilia A (HA). Patients with high-titre inhibit...

Brain Activity and Network Interactions in the Impact of Internal Emotional Distraction.

Emotional distraction may come from the external world and from our mind, as internal distraction. Although external emotional distraction has been extensively investigated, less is known about the me...

News Articles [482 Associated News Articles listed on BioPortfolio]

Bisphenol A exposure during early pregnancy impairs uterine spiral artery remodeling and provokes intrauterine growth restriction in mice

Oppenheimer debunks ‘competitor myths’ surrounding Portola Pharmaceuticals’ AndexXa bleeding antidote

The analysts thumped the table for AndexXa forecasting peak sales of US$1.25bn in 2029

Senator Hatch Calls Out IPR Flaws

During today’s Senate Judiciary hearing, Senator Orrin Hatch addressed the dysfunctional interplay of the inter ...

Verseon to Initiate Phase I Study to Evaluate a New Precision Oral Anticoagulant with Reduced Bleeding Risk

Verseon will be starting a first-in-human phase I trial in Australia for its lead-PROAC (PRecision Oral AntiCoagulant) VE-1902, which has successfully completed regulatory ...

Heavy menstrual bleeding: diagnosis and management options

Heavy menstrual bleeding has a major impact on a woman’s quality of life. This article covers the most recent guidance and available treatment options.

China Biologic Receives CFDA Clinical Trial Approval for Human Fibrin Sealant

BEIJING, June 11, 2018 /PRNewswire/ -- China Biologic Products Holdings, Inc. (NASDAQ: CBPO) ("China Biologic" or the "Company"), a leading fully integrated plasma-based biopharm...

Verseon Presents New Data on its Precision Oral Anticoagulants at BIO International Convention

Verseon presented new preclinical data on its novel class of precision oral anticoagulants (PROACs) at last week’s BIO International Convention in Boston. Verseon’s PRO...

Impact of Microbleeds on Anticoagulation-Related Bleeding After Stroke

In patients with atrial fibrillation and stroke, cerebral microbleeds identified on acute MRI after a stroke were associated with increased risk for intracerebral hemorrhage in the 2 years after post-...

Bleeding disorders advocates host patient fly-in and congressional reception

Patients are asking lawmakers, in person and virtually, to preserve important consumer safeguards, keeping protections for people with preexisting conditions, coverage of an appropriate scope Read...

5-Star Friday: Celebrating some slow journalism

We’ve just wrapped up a busy week of scrutinizing the news coverage of the world’s largest cancer meeting. In many ways medical meetings symbolize what is functional and dysfunctional abou...

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Companies [26 Associated Companies listed on BioPortfolio]

EndoClot Plus, Inc.

EndoClot Plus, Inc. (EPI) is a privately owned company in Santa Clara, California. In collaboration with surgeons and biomaterial scientists, EPI developed a breakthrough technolo...

Saranas Inc.

Saranas is a privately held Houston-based medical device company focused on improving patient outcomes through early detection and monitoring of internal bleeding complications. T...

Embolx, Inc.

Embolx is an emerging commercial-stage medical device company in Silicon Valley developing microcatheters for arterial embolization procedures. Embolx is committed to dramatically...

Saranas, Inc.

Saranas is a privately held Houston-based medical device company focused on improving patient outcomes through early detection and monitoring of internal bleeding complications. T...

Starch Medical Inc.

Starch Medical Inc. (SMI) was founded in 2007 and is a privately held San Jose, California based medical device company engaged in the design, manufacture and sale of absorbable h...

Acessa Health Inc.

The Acessa System is the only radiofrequency ablation system cleared by the U.S. Food and Drug Administration and CE marked for use in percutaneous, laparoscopic coagulation and a...

Saranas

Saranas is a privately held Houston, Texas-based medical device company focused on improving patient outcomes through early detection of internal bleeding complications. The compa...

HemoSonics

HemoSonics is a medical device company with the goal of improving outcomes and reducing healthcare costs by enabling more targeted selection and dosing of blood products in critic...

ISTH

Founded in 1969, the International Society on Thrombosis and Haemostasis (ISTH) is the leading worldwide not-for-profit organization dedicated to advancing the understanding, prev...

Radius

RAD1901 is a potential first-in-class novel selective estrogen receptor modulator (SERM) under development at Radius for menopausal hot flashes. SERMs are small molecules that bind to and selectively ...

Clinical Trials [1968 Associated Clinical Trials listed on BioPortfolio]

Percutaneous Tibial Nerve Stimulation - an Alternative Treatment Option for Chronic Therapy Resistant Anal Fissure

At a tertiary referral centre, 10 patients (4 male and 6 female; mean age 49.8 years) were given neuromodulation via the posterior tibial nerve to the sacral nerve for 30 min on 10 consecu...

Safety and Effectiveness of Low Dose Edoxaban in Patients With NVAF

The efficacy and safety of edoxaban has not been adequately studied in Asians versus non-Asians, who are quite different physiologically from each other. Compared with non-East Asian patie...

Suggesting Score Scale for Risk of Bleeding in Bariatric Surgery

As bleeding is a major risk in bariatric surgeries, we aimed our study to find any predictors to such bleeding within the surgery or 30 days after surgery. Our study is a retrospective stu...

Relation Between Human Epididymis Protein 4 (HE4) and Endometrial Pathology in Patients With Postmenopausal Bleeding

All patients included in the study had single or multiple episodes of postmenopausal bleeding with an endometrial thickness of more than 5mm. full history, general and local examination w...

CHAOS Registry Study

INTRODUCTION: About 6-8% of patients undergoing PCI have an indication for long-term oral anticoagulants (OACs) due to various conditions such as atrial fibrillation (AF), mechanical heart...

TNF-α/HIF-1α/VEGF Pathway in Periodontal Diseases

This study aimed to investigate gingival crevicular fluid (GCF) and salivary hypoxia inducible factor-1 alpha (HIF-1α), vascular endothelial growth factor (VEGF) and tumor necrosis factor...

Over-the-scope Clip Versus Through-the-scope Clip for Endoscopic Hemostasis of High Risk Bleeding Peptic Ulcers

To compare in a multicenter, prospective, randomized, controlled trial the efficacy and safety of OTSC versus TTS clip for first-line hemostasis of high risk bleeding peptic ulcers

A Quality Improvement Project - Peripartum Operating Room Leveling System

Investigators propose a four-category triaging system to delineate and facilitate the communication and action plan for all types of obstetric OR cases via a multidisciplinary approach. In...

A Study of Fitusiran (ALN-AT3SC) in Severe Hemophilia A and B Patients With Inhibitors Previously Receiving Bypassing Agent Prophylaxis

This is a global study of patients with severe hemophilia and inhibitors. The study will characterize the frequency of bleeding episodes while receiving fitusiran, relative to the frequenc...

Delayed Cord Clamping in Infants Born by Cesarean Section

Introduction: Placental transfusion supports an important blood transfer to the neonate, promoting a more stable and smooth transition from fetal to extra-uterine life. Cesarean section, e...

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Medical and Biotech [MESH] Definitions

Abnormal uterine bleeding that is not related to MENSTRUATION, usually in females without regular MENSTRUAL CYCLE. The irregular and unpredictable bleeding usually comes from a dysfunctional ENDOMETRIUM.

Bleeding from blood vessels in the UTERUS, sometimes manifested as vaginal bleeding.

The use of embolizing agents to block the arterial blood supply to parts or all of the UTERUS. The procedures are done to control bleeding or to cause destruction of uterine tissues.

UTERINE BLEEDING from a GESTATION of less than 20 weeks without any CERVICAL DILATATION. It is characterized by vaginal bleeding, lower back discomfort, or midline pelvic cramping and a risk factor for MISCARRIAGE.

Premature separation of the normally implanted PLACENTA from the UTERUS. Signs of varying degree of severity include UTERINE BLEEDING, uterine MUSCLE HYPERTONIA, and FETAL DISTRESS or FETAL DEATH.

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