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EGF receptor Mab human rDNA Amgen - Biotech, Pharma and Life Science Channel

15:44 EDT 21st July 2018 | BioPortfolio

PubMed Articles [27017 Associated PubMed Articles listed on BioPortfolio]

Baohuoside-I suppresses cell proliferation and migration by up-regulating miR-144 in melanoma.

Baohuoside-I was reported to induce apoptosis in non-small-cell lung cancer and inhibit the growth of multiple myeloma cells. The antitumour potential of baohuoside-I has not been demonstrated in mela...

Singular stochastic control model for algae growth management in dam downstream.

A stochastic control model for finding an ecologically sound, fit-for-purpose dam operation policy to suppress bloom of attached algae in its downstream is presented. A singular exactly solvable and a...

Parents' concerns regarding the growth characteristics of their adolescents: a qualitative inquiry in Iran.

In recent times, parents have become increasingly concerned, both subjectively and objectively, about their adolescents' body height/weight growth. Parent-adolescent interactions about this issue and ...

Pentabromopseudilin: a myosin V inhibitor suppresses TGF-β activity by recruiting the type II TGF-β receptor to lysosomal degradation.

Pentabromopseudilin (PBrP) is a marine antibiotic isolated from the marine bacteria Pseudomonas bromoutilis and Alteromonas luteoviolaceus. PBrP exhibits antimicrobial, anti-tumour, and phytotoxic act...

Structural re-positioning, in silico molecular modelling, oxidative degradation, and biological screening of linagliptin as adenosine 3 receptor (ADORA3) modulators targeting hepatocellular carcinoma.

Chemical entities with structural diversity were introduced as candidates targeting adenosine receptor with different clinical activities, containing 3,7-dihydro-1H-purine-2,6-dione, especially adenos...

Newer human inosine 5'-monophosphate dehydrogenase 2 (hIMPDH2) inhibitors as potential anticancer agents.

Human inosine 5'-monophosphate dehydrogenase 2 (hIMPDH2), being an age-old target, has attracted attention recently for anticancer drug development. Mycophenolic acid (MPA), a well-known immunosuppres...

Modulation of cytokine/chemokine production in human macrophages by bisphenol A: A comparison to analogues and interactions with genistein.

The immunotoxicant bisphenol A (BPA) may produce toxic effects on organs and systems, in part, by altering the secretion of cytokines and chemokines. However, systematic studies of the effects of BPA,...

Proanthocyanidins: novel treatment for psoriasis that reduces oxidative stress and modulates Th17 and Treg cells.

Psoriasis is a common, chronic, inflammatory skin disease that affects 2%-4% of the global population. Recent studies have shown that increased oxidative stress (OS) and T-cell abnormalities are centr...

Licorice root extract and magnesium isoglycyrrhizinate protect against triptolide-induced hepatotoxicity via up-regulation of the Nrf2 pathway.

Triptolide, the predominant biologically active component of the Chinese herb Tripterygium wilfordii Hook f., possesses numerous pharmacological activities, including anti-inflammatory, anti-fertility...

l-Peptide functionalized dual-responsive nanoparticles for controlled paclitaxel release and enhanced apoptosis in breast cancer cells.

Nanoparticles and macromolecular carriers have been widely used to increase the efficacy of chemotherapeutics, largely through passive accumulation provided by their enhanced permeability and retentio...

News Articles [10687 Associated News Articles listed on BioPortfolio]

20182023 Global Insulating Adhesive Tape Consumption Market Report [Report Updated: 06062018] Prices from USD $4660

In this report, LP Information covers the present scenario with the base year being 2017 and the growth prospects of global Insulating Adhesive Tape market for 20182023.Insulating Adhesive Tape is a t...

Bangladesh Mustard Oil Market Growth, Trends and Forecasts 2018 2023 [Report Updated: 01032018] Prices from USD $3250

The Bangladesh mustard oil market is expected to register a CAGR of 5.6% during the forecast period, 2018 to 2023. As mustard oil is a commoditybased product, the more the availability, the higher the...

This Week’s Awesome Stories From Around the Web (Through July 21)

FUTURE OF WORK This Is What Work Will Look Like in 2100 Jared Lindzon | Fast Company “Some futurists believe that automation will push future workers to tasks that are quintessentially huma...

The function of the junk jumping gene (LINE1) uncovered

Reporter and Curator: Dr. Sudipta Saha, Ph.D.   Long interspersed nuclear elements 1 (LINE1) is repeated half a million times in the human genome, making up nearly a fifth of the DNA in every cel...

20182023 Global Wound Care Biologics Consumption Market Report [Report Updated: 06062018] Prices from USD $4660

In this report, LP Information covers the present scenario with the base year being 2017 and the growth prospects of global Wound Care Biologics market for 20182023.Wound Care Biologics is an evolving...

Global Lubricant Additives Market Segmented by Type, by Enduser Industry, by Application, and Geography Growth, Trends and Forecasts 2018 2023 [Report Updated: 08022018] Prices from USD $1923

The global lubricant additive market was valued at USD 15,240.70 million in 2017 and is projected to reach USD 18,325.77 million by 2023, at a CAGR of 3.12% during the forecast period, 20182023. By lu...

Uveal melanoma| A Pipeline Analysis Report 2018| Technavio

Technavio has announced their latest pipeline analysis report on the uveal melanoma market. The report includes a detailed analysis of the pipeline molecules under investigation w...

Urinary Incontinence Therapeutics | A Pipeline Analysis Report 2018 | Technavio

Technavio has announced their latest pipeline analysis report on the urinary incontinence therapeutics market. The report includes a detailed analysis of the pipeline molecules un...

Hypogonadism | A Pipeline Analysis Report 2018 | Technavio

Technavio has announced their latest pipeline analysis report on the hypogonadism market. The report includes a detailed analysis of the pipeline molecules under investigation wit...

Global Liquid Biopsy Market 2018-2022| 34% CAGR Projection Over the Next Four Years| Technavio

The global liquid biopsy market 2018-2022 is expected to post a CAGR of more than 34% during the forecast period, according to the latest market research report by Technavio. ...

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Companies [794 Associated Companies listed on BioPortfolio]

Verge Genomics

Verge Genomics is a next-generation drug discovery company that is using human genomics to accelerate drug discovery. Founded by scientists from leading genomics labs and pharmace...

BioNTech and Genevant Sciences

BioNTech is Europe’s largest privately-held biopharmaceutical company pioneering the development of individualized therapies for cancer and other diseases. The Company combin...

Techcyte, Inc.

Headquartered in Orem, Utah, Techcyte, Inc. was founded in 2013 as a tech transfer from the University of Utah with a mission to lower healthcare costs through artificial intellig...

Reapplix

Reapplix has developed a novel platform technology for regenerative medicine which provides cells and growth factors concentrated from a small sample of the patient’s own blo...

MediSked

Founded in 2003, MediSked is the trusted partner to human services organizations in 39 states, the District of Columbia, and Puerto Rico, delivering long- term service and support...

Advanced BioNutrition Corp.

Advanced BioNutrition (ABN) is a biotech company with existing proprietary products and a strong pipeline of new products and technologies that impact animal health and human nutrition. ABN is headqua...

Hu-manity.co

Hu-manity.co is the world’s first and only organization developing human rights and corollary sovereign laws in a decentralized manner on blockchains. The company has headqua...

Arcus Biosciences

Arcus Biosciences (“Arcus”) is a biotechnology company focused on the discovery and development of innovative cancer immunotherapies. Arcus was founded in 2015 by Ter...

Seed 2 Growth Ventures

Seed was founded to pioneer the application of microbiome science to improve human and planetary health. In collaboration with leading scientists and a global network of partners ...

TILT Biotherapeutics Ltd

TILT Biotherapeutics is the leading company globally working in the area of enabling tumor T-cell therapy (including checkpoint antibodies) with oncolytic viruses. The companyâ€...

Clinical Trials [9618 Associated Clinical Trials listed on BioPortfolio]

Effect of Aerobic Exercise Associated With Abdominal Radiofrequency on on Adipose Tissue in Women:

The purpose of the present study was to evaluate the effects of one session of aerobic exercise associated with radiofrequency in lipolytic activity and lipid profile.

Active Surveillance and Chemotherapy Before Surgery in Treating Participants With Stage II-III Rectal Cancer

This pilot trial studies how well active surveillance and chemotherapy before surgery work in treating participants with stage II-III rectal cancer. Active surveillance involves monitoring...

Prospective Thinking in Hormone-Responsive Breast Cancer

One factor that limits the effectiveness of adjuvant hormone therapy for breast cancer is medication nonadherence. Adherence to long-term medication regimens requires valuation of temporal...

Compassionate Use of CAR T Cells Targeting the CD19 Antigen and Containing the Inducible Caspase 9 Safety Switch

This protocol for compassionate use combines 2 different ways of fighting disease: antibodies and T cells. Both antibodies and T cells have been used to treat patients with cancers, and bo...

A Phase 1b/2 Study of Alvocidib Plus Decitabine in Patients With MDS

Alvocidib, a cyclin-dependent kinase 9 (CDK 9) inhibitor, in time-sequential therapy demonstrated significant clinical activity in secondary AML patients with prior MDS. Patients with IPSS...

Phase II Dose Finding AutoImmune Hepatitis

This is a Phase IIa open label adaptive design dose finding study in male and female patients with autoimmune hepatitis (AIH) with compensated liver function currently under standard of ca...

Phase 2 Dose Finding sPIF in Patients With High Panel Reactive Antibodies

This is an open labeled dose finding adaptive design study. Patients with elevated cPRA values, 30-60% will be recruited and administered sPIF injected subcutaneously for 14 doses; one dos...

LMWH-VTE Prophylaxis for Survivors of Acute Ischemic Stroke- Assessment of Standard Dosing Regimen

The anti-factor Xa (anti-Xa) assay is a functional assay that facilitates the measurement of antithrombin (AT)-catalyzed inhibition of factor Xa by unfractionated heparin (UFH) and direct ...

Evaluation of Safety Following Immune Tolerance Induction Treatment With Turoctocog Alfa in Patients With Haemophilia A Following Inhibitor Development in NN7170-4213 Trial

This trial is conducted in Asia, Europe and the United States of America (USA). The aim of the trial is to evaluate safety of immune tolerance induction (ITI) treatment with turoctocog alf...

A Phase 1 Study of HLX20, a Human Monoclonal Antibody Targeting PD-L1Protein in Patients With Advanced Solid Tumors

This is an open-label, dose escalation, first-in-human study of HLX20, an anti-PD-L1 monoclonal antibody, in patients with metastatic or recurrent solid tumors who have failed standard the...

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Medical and Biotech [MESH] Definitions

A vascular endothelial growth factor that specifically binds to VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2 and VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-3. In addition to being an angiogenic factor it can act on LYMPHATIC VESSELS to stimulate LYMPHANGIOGENESIS. It is similar in structure to VASCULAR ENDOTHELIAL GROWTH FACTOR D in that they both contain N- and C-terminal extensions that were not found in other VEGF family members.

A vascular endothelial growth factor that specifically binds to VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2 and VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-3. In addition to being an angiogenic factor it can act on LYMPHATIC VESSELS to stimulate LYMPHANGIOGENESIS. It is similar in structure to VASCULAR ENDOTHELIAL GROWTH FACTOR C in that they both contain N- and C-terminal extensions that were not found in other VEGF family members.

A vascular endothelial cell growth factor receptor whose expression is restricted primarily to adult lymphatic endothelium. VEGFR-3 preferentially binds the vascular endothelial growth factor C and vascular endothelial growth factor D and may be involved in the control of lymphangiogenesis.

A vascular endothelial growth factor expressed in a variety of tissues. It binds with high specificity to VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1 and NEUROPILIN-1.

A 200-230-kDa tyrosine kinase receptor for vascular endothelial growth factors found primarily in endothelial and hematopoietic cells and their precursors. VEGFR-2 is important for vascular and hematopoietic development, and mediates almost all endothelial cell responses to VEGF.

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