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Hypothalamic Controls - Biotech, Pharma and Life Science Channel

22:06 EDT 18th October 2017 | BioPortfolio

PubMed Articles [3930 Associated PubMed Articles listed on BioPortfolio]

Interlaboratory validation of an improved method for detection of Cyclospora cayetanensis in produce using a real-time PCR assay.

A collaborative validation study was performed to evaluate the performance of a new U.S. Food and Drug Administration method developed for detection of the protozoan parasite, Cyclospora cayetanensis,...

An automated approach for early detection of diabetic retinopathy using SD-OCT images.

  This study was to demonstrate the feasibility of an automatic approach for early detection of diabetic retinopathy (DR) from SD-OCT images. These scans were prospectively collected from 200 subject...

Centchroman: A safe reversible postcoital contraceptive with curative and prophylactic activity in many disorders.

Centchroman (INN: Ormeloxifene), a reversible post-coital/weekly oral contraceptive (half-life of about 168 hours), designed and developed at CDRI, Lucknow is the only non-steroidal oral contraceptive...

53BP1: A guardian for centrosomal integrity.

53BP1 is known as a mediator in DNA damage response and a regulator of DNA double-stranded breaks (DSBs) repair. 53BP1 was recently reported to be a centrosomal protein and a binding partner of mitoti...

Biomineralized diamond-like carbon films with incorporated titanium dioxide nanoparticles improved bioactivity properties and reduced biofilm formation.

Recently, the development of coatings to protect biomedical alloys from oxidation, passivation and to reduce the ability for a bacterial biofilm to form after implantation has emerged. Diamond-like ca...

Dementia with Lewy bodies: cerebrospinal fluid suppresses neuronal network activity.

One of the core clinical criteria of Dementia with Lewy bodies (DLB) are fluctuations of cognition. Underlying processes may be rather functional than neurodegenerative, reflected by, for example, fac...

Nervous system delivery of antilysophosphatidic acid antibody by nasal application attenuates mechanical allodynia after traumatic brain injury in rats.

Lysophosphatidic acid (LPA) is a bioactive lipid that impacts neurological outcomes after neurotrauma by inhibiting neuroregeneration, promoting inflammation, and contributing to behavioral deficits. ...

mRNA-Seq reveals accumulation followed by reduction of small nuclear and nucleolar RNAs in yeast exposed to antiviral ribavirin.

Ribavirin is an antiviral drug that is used to treat a wide range of human viral infections. However, the side effects are reported, and the mechanisms on eukaryotic cells are still largely unknown. H...

A multicomponent microemulsion using rational combination strategy improves lung cancer treatment through synergistic effects and deep tumor penetration.

Previously, we have developed a multicomponent-based microemulsion composed of etoposide, coix seed oil, and ginsenoside Rh2 (ECG-MEs). In this study, our goal was to validate the feasibility of ECG-M...

Clinical Usefulness of Human Epididymis Protein 4 in Lung Cancer.

Human epididymis protein 4 (HE4) has been suggested as a useful new biomarker of lung cancer; however, few relevant large-scale studies have been published. In this study, we evaluated the utility of ...

News Articles [424 Associated News Articles listed on BioPortfolio]

Mfsd2b is essential for the sphingosine-1-phosphate export in erythrocytes and platelets

Sphingosine-1-phosphate (S1P), a potent signalling lipid secreted by red blood cells and platelets, plays numerous biologically significant roles. However, the identity of its long-sought exporter is ...

Social behaviour shapes hypothalamic neural ensemble representations of conspecific sex

All animals possess a repertoire of innate (or instinctive) behaviours, which can be performed without training. Whether such behaviours are mediated by anatomically distinct and/or genetically specif...

Nature or nurture? Innate social behaviors in the mouse brain

The brain circuitry that controls innate, or instinctive, behaviors such as mating and fighting was thought to be genetically hardwired. Not so, neuroscientists now say.

Global and Regional Automotive Ambient Lighting Market Research Report 2017 [Report Updated: 04102017] Prices from USD $3500

SummaryMost ambient lighting today reflects a light source off interior surfaces and is designed to help the driver see when he or she enters or exits the vehicle, manipulate driving controls, and imp...

Mouse studies shed light on how protein controls heart failure

(Johns Hopkins Medicine) A new study on two specially bred strains of mice has illuminated how abnormal addition of the chemical phosphate to a specific heart muscle protein may sabotage the way the p...

Roles of BCCIP deficiency in mammary tumorigenesis

Dysregulated DNA repair and cell proliferation controls are essential driving forces in mammary tumorigenesis. BCCIP was originally identified as a BRCA2 and CDKN1A interacting protein that has been i...

A New Edition of New Genetics and Society is Now Available

New Genetics and Society (vol. 36, no. 3, 2017) is available online by subscription only. Articles include: “Regulatory Controls for Direct-to-Consumer Genetic Tests: A Case Study on How the FD...

Global Drug Screening Market by Product amp; Services [Equipment Immunoassay Analyzers, Chromatography Instruments, Breath Analyzers Semiconductor Breath Analyzers, Fuel Cell Analyzers, Rapid Testing DevicesRTD Oral Fluid Testing Devices, Urine Testing De

Drug screening is a type of test carried out to determine an individual's scope and degree of drug abuse. The global drug screening market is expected to reach $9,447 million in 2023 from $5,214 milli...

Venezuela opposition seeks election victory over Maduro

By Andrew Cawthorne and Maria Ramirez CARACAS/PUERTO ORDAZ (Venezuela) (Reuters) - Venezuela's political crisis shifted from barricades to ballots on Sunday with nationwide gubernatorial elections li...

Kurds block Iraqi forces' access to Kirkuk oil fields; Iran shuts border crossings

By Maher Chmaytelli BAGHDAD (Reuters) - Kurdish Peshmerga fighters rejected a warning from an Iraqi paramilitary force to withdraw from a strategic junction south of Kirkuk, which controls access to ...

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Companies [46 Associated Companies listed on BioPortfolio]

BioProcess Technology Consultants, Inc.

Founded in 1994, BioProcess Technology Consultants is the recognized worldwide leader in biologics Chemistry, Manufacturing, and Controls (CMC) consulting, providing a full range ...

Security First Corp.

SecurityFirst provides innovative and affordable software solutions that protect one of the world’s most valuable assets – digital data. SecurityFirst specializes in dat...

BioProcess Technology Consultants Inc.

Founded in 1994, BPTC is the recognized worldwide leader in biologics Chemistry, Manufacturing, and Controls consulting, providing a full range of technical, regulatory, and strat...

Kyriba Corp.

Kyriba is the global leader in cloud treasury solutions, delivering Software-as-a-Service (SaaS) treasury technology to corporate CFOs and Treasurers. More than 1,300 global organ...

Alfresco Software

Alfresco provides modern enterprise content management (ECM) software built on open standards that enables organizations to unlock the power of their business-critical content. Wi...

Excel Dryer, Inc.

For over 50 years, Excel Dryer has been manufacturing the finest American made hand dryers featuring the XLERATOR® Hand Dryer. Excel Dryer is a family owned and operated compan...

Voxello, Inc.

Voxello provides solutions for disabled hospitalized patients who cannot communicate by traditional means. The company’s first product, the noddle™, allows disabled pati...

Degree Controls, Inc.

Indigo-Clean

Indigo-Clean is an affiliate of Kenall Manufacturing, which has earned a reputation for superior quality, innovation, sustainability and exceptional value in the lighting industry...

Intermatic Incorporated

Intermatic has delivered quality products and service to its customers for over 100 years. As a leading manufacturer of controls and energy-management solutions for electrical, HV...

Clinical Trials [1147 Associated Clinical Trials listed on BioPortfolio]

Post-Pregnancy Cardio Trial

Preeclampsia is a systemic pregnancy disorder and is associated with an increased cardiovascular risk later in life. This study will characterize myocardial tissue in patients after preecl...

Trial of Internet-Based Cognitive Behavioral Therapy for Insomnia

The investigators will conduct a randomized, controlled trial of internet-based cognitive behavioral therapy (iCBT) vs usual care for insomnia. The target population is patients prescribed...

Low Dose Exposure to Oxidized R-limonene - A Repeated Open Application Test (ROAT) Study

This study evaluates the clinical and molecular effect of daily exposure to low doses of the fragrance contact allergen oxidized R-limonene. Three groups of participants are included: 1) P...

PREVAIL VII: Persistence of Ebola Virus in Aqueous Humor and Outcomes of Cataract Surgery in Survivors of Ebola Virus Disease

Objective: Zaire ebolavirus is a single-stranded RNA virus associated with high morbidity and mortality. The most recent epidemic of Ebola virus disease (EVD) in West Africa resulted in ov...

E-aid Sleep-focused TrEatment for Prevention of Major Depression (STEP-MD)

In the past, there were studies on relationship between insomnia and depression, and those studies found that depression can be the result of untreated insomnia. Mostly insomnia precedes d...

Oral Health Intervention Program for Children With Congenital Heart Defects

Background: Children with congenital heart defects (CHD) are reported to have poorer oral health compared with healthy children. The aim of the present study was to evaluate the effect of ...

Periodontal Therapy in Thalassemia Major Patients

The study aims to evaluate the effect of local non surgical periodontal therapy on the systemic pro-inflammatory markers in the β-thalassemia (TM-β) patients with chronic periodontitis a...

Single Center Study Evaluating the Possible Effect of Virtual Reality Spectacles on Pain Following Total Knee Replacement Surgery

The trial aims to evaulate the possiblity that use of virtual reality spectacles will affect post operative pain in total knee arthroplasty patients. The trial is a single center open labe...

Sprint Performance in Football Players With a Previous Hamstring Injury

Few studies indicate that sprint performance may be impaired in football players with a previous hamstring strain injury. This exploratory cross-sectional study aim to compare sprint perfo...

Rapid Biochemical Diagnostics of Traumatic Brain Injury

The objective of the study is to confirm the clinical relevance of the novel biomarker for traumatic brain injury (TBI) detection. Samples of blood, urine and saliva will be collected from...

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Medical and Biotech [MESH] Definitions

The part of the hypothalamus posterior to the middle region consisting of several nuclei including the medial mamillary nucleus, lateral mamillary nucleus, and posterior hypothalamic nucleus (posterior hypothalamic area). The posterior hypothalamic area is concerned with control of sympathetic responses and is sensitive to conditions of decreasing temperature and controls the mechanisms for the conservation and increased production of heat.

A collection of NEURONS, tracts of NERVE FIBERS, endocrine tissue, and blood vessels in the HYPOTHALAMUS and the PITUITARY GLAND. This hypothalamo-hypophyseal portal circulation provides the mechanism for hypothalamic neuroendocrine (HYPOTHALAMIC HORMONES) regulation of pituitary function and the release of various PITUITARY HORMONES into the systemic circulation to maintain HOMEOSTASIS.

This area is bounded medially by the mammillothalamic tract and the anterior column of fornix. The medial edge of the internal capsule and the subthalamic region form its lateral boundary. It contains the lateral hypothalamic nucleus, tuberomammillary nucleus, lateral tuberal nuclei, and fibers of the MEDIAL FOREBRAIN BUNDLE. (Parent, Carpenter's Human Neuroanatomy, 9th ed, p710)

The front portion of the HYPOTHALAMUS separated into the preoptic region and the supraoptic region. The preoptic region is made up of the periventricular gray matter of the rostral portion of the third ventricle and contains the preoptic ventricular nucleus and the medial preoptic nucleus. The supraoptic region contains the PARAVENTRICULAR HYPOTHALAMIC NUCLEUS, the SUPRAOPTIC NUCLEUS, the ANTERIOR HYPOTHALAMIC NUCLEUS, and the SUPRACHIASMATIC NUCLEUS.

Cell surface receptors that bind the hypothalamic hormones regulating pituitary cell differentiation, proliferation, and hormone synthesis and release, including the pituitary-releasing and release-inhibiting hormones. The pituitary hormone-regulating hormones are also released by cells other than hypothalamic neurons, and their receptors also occur on non-pituitary cells, especially brain neurons, where their role is less well understood. Receptors for dopamine, which is a prolactin release-inhibiting hormone as well as a common neurotransmitter, are not included here.

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