Advertisement

Topics

Tissue Growth Factors BMP 2 - Biotech, Pharma and Life Science Channel

08:47 EDT 23rd September 2018 | BioPortfolio

The classical tissue factors typically are proteins used for tissue repair and growth stimulation. Among the approved products are the growth factors PDGF, IGF, EGF, BMP and FGF. One of the commercially most successful growth factors is BMP-2 from Medtronic and Pfizer (ex Wyeth) with annual sales of nearly US$ 800 mln and prospect for further growth by use in additional indications. Growth factors are used for treatment of growth failure, skin wounds and ulcers, corneal damage, oral mucositis or to stimulate bone growth. Further growth factors such as HGF, VEGF, TGF, NGF, GDF and quite a number of neurotrophic factors are under development. Apart from proteins as the classical drugs, other classes of compounds are also under development such as small molecules to stimulate growth factor receptors or antibodies to block inhibitory pathways, thereby inducing functional recovery. Furthermore, engineered peptides mimicking growth factors, cells engineered to express growth factors or simply plasmids for growth factors are under development.

News Articles [4226 Associated News Articles listed on BioPortfolio]

Ypsomed Holding AG YPSN Financial and Strategic SWOT Analysis Review [Report Updated: 05072018] Prices from USD $125

Ypsomed Holding AG YPSN Financial and Strategic SWOT Analysis Review provides you an indepth strategic SWOT analysis of the company's businesses and operations. The profile has been compiled by Globa...

Healthcare Providers in Denmark [Report Updated: 20042018] Prices from USD $350

Healthcare Providers in DenmarkSummaryHealthcare Providers in Denmark industry profile provides topline qualitative and quantitative summary information including: market size value 201317, and foreca...

AsiaPacific Pea Protein Market Growth, Trends and Forecasts 2018 2023 [Report Updated: 01032018] Prices from USD $3850

The AsiaPacific pea protein market records a revenue of USD 20.9 million in 2016, and is expected to grow at a CAGR of 8.4% during the forecast period 20182023.The health benefits of protein intake fr...

Novartis to file for new Lucentis® (ranibizumab) indication in retinopathy of prematurity (ROP), a rare disease in premature infants that often leads to blindness

Novartis International AG / Novartis to file for new Lucentis® (ranibizumab) indication in retinopathy of prematurity (ROP), a rare disease in premature infants that often leads to blindness . Pro...

Hesperos, Inc. Among GrowFL 2018 Florida Companies to Watch

Hesperos, Inc. has announced that it has been named one of the 50 statewide companies expected to see significant growth over the next several years by GrowFL. The 50 companies we...

Top-Rated Las Vegas PLANET 13/MEDIZIN Dispensary Reports Record Growth Prior to Planet 13 Superstore Opening -- CFN Media

SEATTLE, Sept. 21, 2018 (GLOBE NEWSWIRE) -- via NEWMEDIAWIRE -- CFN Media Group (“CFN Media”), the leading agency and financial media network dedicated to the North American cannabis industry, ...

Global Optical Coherence Tomography Market 2017-2021 | Conventional OCT Systems Dominates the Global Market | Technavio

According to the market research report released by Technavio, the global optical coherence tomography market is expected to accelerate at a CAGR of more than 8% during the foreca...

Global Ophthalmic Femtosecond Lasers Market 2017-2021| Consumables and Accessories Segment Dominates the Global Market| Technavio

According to the market research report released by Technavio, the global ophthalmic femtosecond lasers market is expected to accelerate at a CAGR of more than 6% during the forec...

Global Optical Imaging Market 2017-2021 | Imaging Systems Dominates the Global Market | Technavio

According to the market research report released by Technavio, the global optical imaging market is expected to accelerate at a CAGR of more than 8% during the forecast period. Th...

Revance Receives Great Place to Work Certification

Revance Therapeutics, Inc. (NASDAQ:RVNC), a biotechnology company developing neuromodulators for use in treating aesthetic and therapeutic conditions, today announced that the com...

Events [0 Results]

None

Companies [602 Associated Companies listed on BioPortfolio]

Anova Cancer Care

Anova Cancer Care serves Denver and the Rocky Mountain region with the world’s only robotic radiosurgery system designed to treat tumors anywhere in the body. Used by the nat...

Blue Ox Healthcare Partners, LLC

Blue Ox Healthcare Partners, LLC is a private equity investment firm focused on providing capital to growth stage healthcare companies targeting the industry’s transformation...

Shore Capital Partners, LLC

Shore Capital is a Chicago-based private equity firm focused exclusively on microcap healthcare investments. Shore supports management partners with capital, business development ...

Personal Genome Diagnostics, Inc.

Personal Genome Diagnostics (PGDx) empowers the fight against cancer by unlocking actionable information from the genome. We are committed to developing a portfolio of regulated t...

Morphogenesis, Inc.

Incorporated in 1995 and based in Tampa, Florida, Morphogenesis is a privately-held emerging biotechnology company structured to serve the rapidly growing multibillion dollar cell...

MarketsandMarkets and SRI International

MarketsandMarkets provides quantified B2B competitive intelligence research on high-growth emerging niche markets that will impact future revenue mix of 70-80 percent of companies...

Linde plc

In the 2016 financial year, The Linde Group generated revenue of EUR 17 billion, making it one of the leading gases and engineering companies in the world, with approximately 60,0...

UF Innovate | Sid Martin Biotech

UF Innovate | Sid Martin Biotech is the leading biotechnology incubator headquartered at the University of Florida in Alachua, Florida at Progress Park. Sid Martin has been honore...

Nagourney Cancer Institute

The Nagourney Cancer Institute is a clinical research center that has pioneered the study of human tumor tissue for individualized cancer patient drug selection and has facilitate...

RTI Donor Services, Inc. and BloodCenter of Wisconsin

BloodCenter of Wisconsin, part of Versiti, is a not-for-profit organization headquartered in Milwaukee, Wis., that specializes in blood services, esoteric diagnostic testing, orga...

Clinical Trials [8249 Associated Clinical Trials listed on BioPortfolio]

The Relationship Between Hypoalbuminemia and Development of Acute Kidney Failure (AKI) According to KDIGO Criteria

This study was designed to determine the association between preoperative and postoperative hypoalbuminemia and AKI in older age hip fracture surgeons, to determine which period of hypoalb...

Study of Human Adipose Tissue (LOSHAT)

The investigators will study the influence of initial fat cell size/number and adipose function (in particular lipolysis) on weight development over very long time periods (years). By comp...

Mucoderm or Connective Tissue Graft for Treatment of Gingival Recessions

Coronally advanced flap plus connective tissue graft (CTG) is the gold standard therapy for root coverage. The bioabsorbable porcine collagen matrix (CM) has been widely used in periodonta...

Adjunctive Hyperbaric Oxygen Therapy (HBOT) for Lower Extermity Diabetic Ulcer:

Diabetic foot ulcers are associated with high risk of amputation. About 50% of patients undergoing non-traumatic lower limb amputations are diabetics5. The 5-year amputation rate is estima...

Neurotrophic Factors, Tight Junction Proteins, and Cytokines in IBS

To evaluate the role of neurotrophic factors (NGF, GDNF, TRPV-1), to quantity tight junction proteins (ZO-1, occludin, claudin) and cytokines (IL-8, TNF-a, IL-1b) in the colonic mucosa of ...

Diagnostic Accuracy of Dermal Thickness in Lymphedema

Ultrasound is an easily feasible noninvasive technique which is widely used in rehabilitation settings. Measurement of dermal thickness via ultrasound can be less time consuming than volum...

LPS and Platelet Activation in Myocardial Infarction

Platelets play a key role in the athero-thrombotic process. However, the in vivo mechanism accounting for thrombus growth at site of coronary atherosclerotic lesion has not been fully eluc...

The Manitoba Personalized Lifestyle Research (TMPLR) Study

Lifestyle factors, such as diet, physical activity and sleep, are associated with the development of many chronic diseases. The objective of The Manitoba Personalized Lifestyle Research (T...

Effect of Puerarin on Heart Health in Men

This study aims to assess the effect of puerarin supplementation on cardiovascular disease risk factors in men.

Hair Growth Efficacy and Safety of NGF-574H in Adult With Androgenic Alopecia

The purpose of this study is to assess whether cosmetic investigational product containing NGF-574H is safe and effective in the treatment of androgenic alopecia in asian adults.

PubMed Articles [21078 Associated PubMed Articles listed on BioPortfolio]

Singular stochastic control model for algae growth management in dam downstream.

A stochastic control model for finding an ecologically sound, fit-for-purpose dam operation policy to suppress bloom of attached algae in its downstream is presented. A singular exactly solvable and a...

Parents' concerns regarding the growth characteristics of their adolescents: a qualitative inquiry in Iran.

In recent times, parents have become increasingly concerned, both subjectively and objectively, about their adolescents' body height/weight growth. Parent-adolescent interactions about this issue and ...

Pentabromopseudilin: a myosin V inhibitor suppresses TGF-β activity by recruiting the type II TGF-β receptor to lysosomal degradation.

Pentabromopseudilin (PBrP) is a marine antibiotic isolated from the marine bacteria Pseudomonas bromoutilis and Alteromonas luteoviolaceus. PBrP exhibits antimicrobial, anti-tumour, and phytotoxic act...

Asynchronous exponential growth for a two-phase size-structured population model and comparison with the corresponding one-phase model.

In this paper we study a two-phase size-structured population model with distributed delay in the birth process. This model distinguishes individuals by 'active' or 'resting' status. The individuals i...

Pragmatic and rapid analysis of carbonyl, oxidation and chlorination nucleoside-adducts in murine tissue by UPLC-ESI-MS/MS.

Nucleoside-adduct analysis by liquid chromatography mass spectrometry is a powerful tool in genotoxicity studies. Efforts to date have quantified an impressive array of DNA damage products, although m...

A novel biosensor based on Au@Ag core-shell nanoparticles for sensitive detection of methylamphetamine with surface enhanced Raman scattering.

We describe a novel biosensing strategy for sensitive detection of methylamphetamine (MAMP) based on surface enhanced Raman scattering (SERS) by the mediation of spacing between 4-mercaptobenzoic acid...

Phenolic acids induced growth of 3D ordered gold nanoshell composite array as sensitive SERS nanosensor for antioxidant capacity assay.

A novel method based on surface-enhanced Raman scattering (SERS) was developed to estimate the reducing capacity of phenolic acids by using self-assembled three-dimensionally (3D) ordered gold nanopar...

Quantitative and qualitative composition of yeast microbiota in spontaneously fermented grape musts obtained from cool climate grape varieties 'Rondo' and 'Regent'.

The aim of the study was to characterise, quantitatively and qualitatively, the yeast microbiota found during spontaneous fermentation of grape musts obtained from the red grape varieties 'Rondo' and ...

Clinical and genetic analysis of distal renal tubular acidosis in three Chinese children.

Primary distal renal tubular acidosis (dRTA) is a rare genetic disease characterized by distal tubular dysfunction leading to metabolic acidosis and alkaline urine. Growth retardation is a major conce...

Water disinfection by hydrodynamic cavitation in a rotor-stator device.

The efficiency of a rotor-stator device for water disinfection based on hydrodynamic cavitation is investigated. Water is infected with E. coli and E. faecalis with initial concentrations in the range...

Videos

None available.

Medical and Biotech [MESH] Definitions

These growth factors are soluble mitogens secreted by a variety of organs. The factors are a mixture of two single chain polypeptides which have affinity to heparin. Their molecular weight are organ and species dependent. They have mitogenic and chemotactic effects and can stimulate endothelial cells to grow and synthesize DNA. The factors are related to both the basic and acidic FIBROBLAST GROWTH FACTORS but have different amino acid sequences.

A family of transcription factors that are induced by GROWTH FACTORS and contain a highly conserved DNA-binding domain composed of three ZINC FINGER MOTIFS.

An angiogenic protein belonging to the Vascular Endothelial Growth Factor family of growth factors originally isolated and cloned from human placental cDNA library. There are four isoforms of PLGF 1-4 which result from alternative splicing. Placenta Growth Factor is secreted as a glycosylated homodimer which acts as a mitogen for endothelial cells, and its expression is markedly upregulated during hypoxia and in tissue inflammation and cancer.

Procedures for enhancing and directing tissue repair and renewal processes, such as BONE REGENERATION; NERVE REGENERATION; etc. They involve surgically implanting growth conducive tracks or conduits (TISSUE SCAFFOLDING) at the damaged site to stimulate and control the location of cell repopulation. The tracks or conduits are made from synthetic and/or natural materials and may include support cells and induction factors for CELL GROWTH PROCESSES; or CELL MIGRATION.

These growth factors comprise a family of hematopoietic regulators with biological specificities defined by their ability to support proliferation and differentiation of blood cells of different lineages. ERYTHROPOIETIN and the COLONY-STIMULATING FACTORS belong to this family. Some of these factors have been studied and used in the treatment of chemotherapy-induced neutropenia, myelodysplastic syndromes, and bone marrow failure syndromes.

Advertisement
Quick Search
Advertisement
Advertisement

 

Relevant Topics

The Top 100 Pharmaceutical Companies
Top 10 biotech and pharmaceutical companies worldwide based on market value in 2015 2015 ranking of the global top 10 biotech and pharmaceutical companies based on revenue (in billion U.S. dollars) Johnson & Johnson, U.S. 74...

Dermatology
Acne Dermatology Eczema Psoriasis Wound Care Dermatology is the medical specialty concerned with the diagnosis and treatment of skin disorders (Oxford Medical Dictionary). As well as studying how the skin works, dermatology covers...

Osteoporosis
Osteoporosis is a disease in which the bones become extremely porous, are subject to fracture, and heal slowly, occurring especially in women following menopause and often leading to curvature of the spine from vertebral collapse. Follow and track&n...

review and buy Tissue Growth Factors BMP 2 market research data and corporate reports here

Channels Quicklinks