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Treatment of Pain - Biotech, Pharma and Life Science Channel

07:08 EST 18th November 2017 | BioPortfolio

PubMed Articles [19066 Associated PubMed Articles listed on BioPortfolio]

Current Treatment of Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis.

Treatment of nonalcoholic fatty liver disease (NAFLD)/nonalcoholic steatohepatitis (NASH) is focused on patients with NASH because they are at highest risk for progressive liver disease. Current first...

Chemotherapy-Associated Peripheral Neuropathy in Patients With Early-Stage Breast Cancer: A Systematic Review.

Breast cancer is the most common cancer among women worldwide, and survival rates are increasing. Chemotherapy-associated peripheral neuropathy (PN) is clinically important because of effects on quali...

Long-term Peripheral Neuropathy in Breast Cancer Patients Treated With Adjuvant Chemotherapy: NRG Oncology/NSABP B-30.

The long-term effects of chemotherapy are sparsely reported. Peripheral neuropathy (PN) is one of the most frequent toxicities associated with taxane use for the treatment of early-stage breast cancer...

Interaction of Postmastectomy Radiation Treatment With Breast Reconstruction: Many Questions, Emerging Data.

Expression and X-Ray Structural Determination of the Nucleoprotein of Lassa Fever Virus.

We describe methods to express the nucleoprotein (NP) of Lassa fever virus (LASV) in E. coli, to purify and crystallize it using the sitting-drop vapor diffusion method. The crystals were screened usi...

Xenograft as In Vivo Experimental Model.

The identification of experimental models that recapitulate human cancers designed to predict patient clinical response to therapies is a major break in oncology. Cancer stem cells (CSCs) represent a ...

Abiotic Stress Phenotyping of Polyamine Mutants.

Plant mutants in polyamine pathway genes are ideal for investigating their roles in stress responses. Here we describe easy-to-perform methods for phenotyping Arabidopsis mutants under abiotic stress....

Epigenetic Treatment Options in Urothelial Carcinoma.

Mutations, dysregulation, and dysbalance of epigenetic regulators are especially frequent in urothelial carcinoma (UC) compared to other malignancies. Accordingly, targeting epigenetic regulators may ...

Applicability of the direct injection liquid chromatographic tandem mass spectrometric analytical approach to the sub-ngL(-1) determination of perfluoro-alkyl acids in waste, surface, ground and drinking water samples.

The applicability of a direct injection UHPLC-MS/MS method for the analysis of several perfluoroalkyl acids (PFAAs) in a wide range of water matrices was investigated. The method is based on the direc...

Genetic addiction risk score (GARS) ™, a predictor of vulnerability to opioid dependence.

The interaction of neurotransmitters and genes that control the release of dopamine is the Brain Reward Cascade (BRC). Variations within the BRC, whether genetic or epigenetic, may predispose individu...

News Articles [9228 Associated News Articles listed on BioPortfolio]

US FDA approves Pfizer's Sutent to treat adult patients at high risk of recurrent RCC

Pfizer has announced that the US Food and Drug Administration has approved a new indication expanding the use of Sutent (sunitinib malate) to include the adjuvant treatment of adult patients at high r...

KemPharm Plans To License Out Commercial Rights For Pain, ADHD Candidates

KemPharm hopes a deep-pocketed company with neuroscience experience will want to market its prodrug of Ritalin for ADHD. For acute...   

[Articles] Effect of HIV-1 low-level viraemia during antiretroviral therapy on treatment outcomes in WHO-guided South African treatment programmes: a multicentre cohort study

In this large cohort, low-level viraemia occurred frequently and increased the risk of virological failure and switch to second-line ART. Strategies for management of low-level viraemia need to be inc...

Hodgkin's Lymphoma Forecast in 17 Major Markets 20162026 [Report Updated: 02102016] Prices from USD $4930

Black Swan Analysis Epiomic Epidemiology Series Forecast Report on Hodgkin's Lymphoma in 17 Major MarketsHodgkin's Lymphoma HL is a cancer also known as Hodgkin Disease, Hodgkin Lymphoma or Hodgkin's ...

New study further validates use of vaginal progesterone to decrease risk of preterm birth

A new study published today - World Prematurity Day - in the American Journal of Obstetrics & Gynecology provides additional support for treatment with vaginal progesterone to reduce the risk of prete...

Astrocytes linked to Alzheimer’s disease for the first time.

Alzheimer’s disease (AD) is the most common dementia type, with no treatment to slow down the progression of the disease currently available. The mechanisms of AD are poorly understood with drug...

Global Seed Treatment Market Research Report Forecast 2017 to 2021 [Report Updated: 13112017] Prices from USD $2800

The Global Seed Treatment Market Research Report Forecast 20172021 is a valuable source of insightful data for business strategists. It provides the Seed Treatment industry overview with growth analys...

Calmare Therapeutics Inc CTTC Financial and Strategic SWOT Analysis Review [Report Updated: 13112017] Prices from USD $300

SummaryCalmare Therapeutics Inc CTI is a biotherapeutic company that offers pain mitigation and wound care technologies. The company provides nonpharmacological, nonaddictive and noninvasive solution ...

Fasenra (Benralizumab) receives FDA approval for severe eosinophilic asthma

AstraZeneca and its global biologics research and development arm, MedImmune, announced that the FDA has approved FASENRA (benralizumab) for the add-on maintenance treatment of patients with severe ...

FDA gives clearance for opioid addiction withdrawal treatment

The FDA gave clearance  for a neurological device with an indication to aid in the reduction of opioid withdrawal symptoms. The NSS-2 BRIDGE device, pioneered by Indiana-based medical technology fir...

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Companies [564 Associated Companies listed on BioPortfolio]

Foundation for Chiropractic Education

A not-for-profit organization, Foundation for Chiropractic Education (501-(C)(3)) and the Foundation for Chiropractic Progress (501C6) provide information and education regarding ...

Cycle Pharmaceuticals

Cycle Pharmaceuticals is committed to changing the way that HT-1 is treated and managed around the world. Cycle Pharmaceuticals has worked for more than four years closely with ph...

Addiction Treatment Advocacy Coalition

vTv Therapeutics Inc. vTv Therapeutics Inc. vTv Therapeutics Inc.

vTv Therapeutics Inc. is a clinical-stage biopharmaceutical company engaged in the discovery and development of orally administered small molecule drug candidates to fill signific...

Fog Zero

Fog Zero is a cleaning product designed to treat glass and plastic lens surfaces. Fog Zero produces a compact kit that allows for quick and effective treatment of optic lenses. Fo...

iVeena Delivery Systems, Inc.

iVeena Delivery Systems, Inc. (iVeena) is a privately held biopharmaceutical company that develops innovative ophthalmology products. iVeena utilizes a proprietary intracapsular d...

Tear Film Innovations, Inc.

Tear Film Innovations (TFI) is an early-stage company developing break-through products for the treatment of evaporative dry eye and related syndromes including Meibomian Gland Dy...

Graybug Vision, Inc.

Graybug Vision is developing novel products for the treatment of people with ocular diseases. The company’s proprietary injectable products are designed to enable less freque...

EUSA Pharma

EUSA Pharma is a rapidly growing transatlantic specialty pharmaceutical company focused on in-licensing, developing and marketing late-stage oncology, pain control and critical care products. The ...

Sanofi Genzyme

Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, prov...

Clinical Trials [5607 Associated Clinical Trials listed on BioPortfolio]

Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), Food-effect of TRK-750

This is an exploratory, randomised, double-blind, placebo-controlled, Phase I study to assess the safety, tolerability, pharmacokinetics, pharmacodynamics and food-effect of single and mul...

Neurophysiological Effects of Dry Needling in Patients With Neck Pain

The present study aims to evaluate the differences that may be experienced in pain and cervical disability, before, during and just after the intervention of the Deep Dry Needling in the u...

Dependence on Analgesics in Chronic Non-cancer Pain

The identification of an addiction to opioid analgesics has become strong recommendation for the purpose of improving the clinical management of the patients. However, the success of the p...

Vectors Post Market: A Study to Assess Pain Relief Using Spinal Cord Stimulation

This is a prospective, single-arm, multi-center study evaluating the efficacy of spinal cord stimulation (SCS) therapy for pain relief using high dose (HD) stimulation parameters delivered...

Smart Phone ACT Treatment for Adults With Longstanding Pain - a Pilot Study

The aims are to test feasibility and preliminary effects of a smart phone delivered ACT treatment for adults with longstanding pain. The hypotheses are that 1. ACTsmart will be a...

Biologic Mechanisms for Pain Variation After Physical Activity in Osteoarthritis

Osteoarthritis (OA) in the knee is characterized by chronic inflammatory pain that is not necessarily related to the amount of joint damage. Clinical practice guidelines recommend physical...

The Efficacy of Radial Extracorporeal Shockwave Therapy on Knee Osteoarthritis - A Double-blind Randomized Trial

This is a double-blind placebo controlled trial whose objective is to understand how much the radial extracorporeal shockwave therapy can improve function of patients with knee osteoarthri...

Adenosine and Magnesium Sulphate as Adjuvants for PECS Block.

Pectoral nerve block (PECS) has been used for post-operative pain relief in patients undergoing breast surgery. It has been shown that adenosine has an effect on pain modulation. Magnesium...

SafERteens M-Coach

This study will use a SMART (Sequential, Multiple Assignment Randomized Trial) design to optimize adaptive interventions (AIs) for adolescents reporting alcohol misuse and violent behavior...

Kinetic Anesthesia Device Study

Patients experience discomfort from lidocaine injections. Vibrating kinetic anesthesia devices have been shown to reduce pain of injections in dentistry, pediatrics, and dermatology, thoug...

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Medical and Biotech [MESH] Definitions

Persistent pain that is refractory to some or all forms of treatment.

A type of pain that is perceived in an area away from the site where the pain arises, such as facial pain caused by lesion of the VAGUS NERVE, or throat problem generating referred pain in the ear.

A syndrome characterized by retropatellar or peripatellar PAIN resulting from physical and biochemical changes in the patellofemoral joint. The pain is most prominent when ascending or descending stairs, squatting, or sitting with flexed knees. There is a lack of consensus on the etiology and treatment. The syndrome is often confused with (or accompanied by) CHONDROMALACIA PATELLAE, the latter describing a pathological condition of the CARTILAGE and not a syndrome.

An opioid analgesic with actions and uses similar to those of MORPHINE, apart from an absence of cough suppressant activity. It is used in the treatment of moderate to severe pain, including pain in obstetrics. It may also be used as an adjunct to anesthesia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1092)

A nonsteroidal anti-inflammatory agent with potent analgesic and antiarthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ankylosing SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).

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