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Triggers - Biotech, Pharma and Life Science Channel

19:10 EDT 21st October 2017 | BioPortfolio

PubMed Articles [633 Associated PubMed Articles listed on BioPortfolio]

Enzymatically modified LDL, atherosclerosis and beyond: paving the way to acceptance.

The eLDL (enzymatically modified LDL) hypothesis proposes that modification of LDL during atherogenesis occurs through the action of ubiquitous hydrolytic enzymes. eLDL is recognized by multiple macro...

Bioinvasion Triggers Rapid Evolution of Life Histories in Freshwater Snails.

Biological invasions offer interesting situations for observing how novel interactions between closely related, formerly allopatric species may trigger phenotypic evolution in situ. Assuming that succ...

A RHIM with a View: FLYing with Functional Amyloids.

Recognition of bacterial peptidoglycan by the Drosophila IMD pathway triggers NF-κB activation and an associated immune response. In this issue of Immunity, Kleino et al. (2017) show that proteins i...

Absence of RNase H2 triggers generation of immunogenic micronuclei removed by autophagy.

Hypomorphic mutations in the DNA repair enzyme RNase H2 cause the neuroinflammatory autoimmune disorder Aicardi-Goutières syndrome (AGS). Endogenous nucleic acids are believed to accumulate in patien...

Hepatic T Cell Tolerance Induction in An Inflammatory Environment.

For the development of autoimmune hepatitis (AIH), genetic predisposition and environmental triggers are of major importance. Although experimental AIH can be induced in genetically susceptible mice, ...

Seasonal and circadian biases in bird tracking with solar GPS-tags.

Global Positioning System (GPS) tags are nowadays widely used in wildlife tracking. This geolocation technique can suffer from fix loss biases due to poor satellite GPS geometry, that result in tracki...

EroS enzyme from Aliivibrio fischeri plays Cupid to choanoflagellates.

A collaborative effort by the King and Clardy laboratories serendipitously identified a bacterial chondroitinase that triggers the choanoflagellate S. rosetta to swarm and sexually reproduce.

Prevalence and outcomes of cystic lesions of the transplant pancreas: The University of Wisconsin Experience.

Literature on the behavior of cystic lesions in pancreas transplants is scarce, and hence a better understanding is warranted. Data on recipients and their respective donors that underwent simultaneou...

Paclitaxel Reduces Axonal Bclw to Initiate IP3R1-Dependent Axon Degeneration.

Chemotherapy-induced peripheral neuropathy (CIPN) is a debilitating side effect of many cancer treatments. The hallmark of CIPN is degeneration of long axons required for transmission of sensory infor...

Innate Immune Recognition of Double-stranded RNA Triggers Increased Expression of NKG2D Ligands After Virus Infection.

Self/non-self discrimination by the innate immune system relies on germline-encoded, non-rearranging receptors expressed by innate immune cells recognizing conserved pathogen-associated molecular patt...

News Articles [186 Associated News Articles listed on BioPortfolio]

Exercising With Asthma or Allergies

FRIDAY, Oct. 20, 2017 -- Allergies and asthma can make exercise more challenging. But if your condition is well managed and you take a few precautions, you should be able to work out without worry. Kn...

FibroGen Says CFDA Accepts Novel Anemia NDA for Review

FibroGen, a US-China biopharma, reported the CFDA has accepted an NDA to review its novel anemia treatment for China approval. Roxadustat is a first-in-class oral treatment for anemia in patients unde...

Gene circuit switches on inside cancer cells, triggers immune attack

(Massachusetts Institute of Technology) Researchers at MIT have developed a synthetic gene circuit that triggers the body's immune system to attack cancers when it detects signs of the disease.

Menopause Triggers Brain Changes Linked to Alzheimer's

New research may explain why women are more prone to develop Alzheimer's disease and points to potential avenues for early intervention. Medscape Medical News

Menopause triggers metabolic changes in the brain that increase women’s risk of Alzheimer’s – Daily Mail

Daily MailMenopause triggers metabolic changes in the brain that increase women's risk of Alzheimer'sDaily MailGoing through menopause may increase women's risk of developing Alzheimer's disease, a ne...

ADC Therapeutics Triggers Second Target-Specific License to Synaffix ADC Platform under Existing Agreement

Synaffix BV announced today that ADC Therapeutics has triggered a second target-specific license under their Commercial License Agreement dated October 2016, to develop an antib...

Medical News Today: Menopause may trigger Alzheimer's disease

A new study looked at the metabolic changes in the brains of menopausal and perimenopausal women and found potential triggers for Alzheimer's disease.

ADC Therapeutics Triggers Second Target-Specific License to Synaffix ADC Platform under ...

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ADC Therapeutics Triggers Second Target-Specific License To Synaffix ADC Platform Under Existing Agreement

AMSTERDAM--(BUSINESS WIRE)--Synaffix BV announced today that ADC Therapeutics has triggered a second target-specific license under their Commercial License Agreement dated October 2016, to...

Flu vaccines to be given to all children

All two to 17-year-olds in the UK are to be offered flu vaccinations each winter in a significant shift in UK immunisation policy. Up to nine million children will be eligible for a new nasal spray va...

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Companies [4 Associated Companies listed on BioPortfolio]

OsteoStrong

OsteoStrong leverages clinically researched osteogenic stimulation methodology to help people of all ages and fitness levels enhance bone health, balance, overall strength, and po...

BiondVax Pharmaceuticals Ltd

BiondVax is a publicly traded (TASE: BNDX), advanced clinical stage biotech company dedicated to improving protection against influenza, with its lead product a universal influenza (flu) vaccine cal...

MaxPoint Interactive

Using its unique Digital Zip technology, MaxPoint Interactive analyzes billions of data points consumed by neighborhoods across the U.S. such as: offline point of sale data...

Adaptimmune Limited

Adaptimmune Limited is focused on the use of T cell therapy to treat HIV and cancer. It aims to utilize the body’s own machinery – the T lymphocyte cell – to target and destroy can...

Clinical Trials [117 Associated Clinical Trials listed on BioPortfolio]

Investigation of Seasonal Variations of Brain Structure and Connectivity in SAD

Seasonal Affective Disorder (SAD) is a subtype of Major Depressive Disorder, characterized by a recurrent temporal relationship between the season of year, the onset and the remission of a...

Factors Influencing Pediatric Asthma

Asthma is a chronic lung disease with serious morbidity and potential mortality. Multiple physiologic, environmental and social conditions impact the prevalence and severity of asthma. Eve...

Effects of Neuromodulation and Rehabilitation of the Locomotor Network in Freezing of Gait

Freezing of gait (FoG) is a common and debilitating condition in Parkinson's Disease (PD) patients. FoG is described as an episodic inability to walk, which often triggers falls, hospitali...

Effects of TENS and IES on the Autonomous Balance of Normotens Volunteers and Hypertensive Patients

Hypertension is considered a serious public health problem. The imbalance in autonomic nervous system (ANS) activity is one of the main triggers in the development and maintenance of hyper...

Asthma Mobile Health Application 2.0

Mobile health applications (MHA) are increasingly being explored as tools to assist in management of chronic diseases. Little is known regarding which characteristics of MHAs are effective...

Pembrolizumab in Combination With Radiotherapy in Locally Advanced Non-Small Cell Lung Cancer (NSCLC)

Lung cancer is the leading cause of cancer mortality worldwide and in the U.K alone; there are 38,000 new cases of non-small cell lung cancer (NSCLC) a year. The new treatment being teste...

Comparative Study to Evaluate the Effectiveness of Atenolol and Propranolol in the Treatment of Infantile Hemangiomas

Through this study, the investigators shall compare the effectiveness of atenolol with propranolol in the treatment of IH. In addition, the investigators shall try to elucidate the mechani...

GLOBAL LEADERS Adjudication Sub-Study

The GLOBAL LEADERS Adjudication Sub-StudY, GLASSY, is based on a re-assessment of all the events reported in the dataset of the parent trial (COMPARATIVE EFFECTIVENESS OF 1 MONTH OF TICAGR...

Epigenetic Regulation of Altered T-cell Immunity in Sarcoidosis

Sarcoidosis is a multi-system granulomatous disorder that is triggered and influenced by gene-environment interactions. Although sarcoidosis predominantly affects the lungs in most cases, ...

Pharmacologically Triggered Migraine Without Aura and Neuroimaging

Migraine is a highly disabling disorder affecting 14% of the general population Worldwide and ranked as the 6th most debilitating disease worldwide by the WHO. One of the most fundamental ...

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Medical and Biotech [MESH] Definitions

A cytokine that promotes differentiation and activation of EOSINOPHILS. It also triggers activated B-LYMPHOCYTES to differentiate into IMMUNOGLOBULIN-secreting cells.

System of psychological and/or therapeutic techniques used to control and or reduce the triggers, degrees, and effects of ANGER.

A constellation of responses that occur when an organism is exposed to excessive cold. In humans, a fall in skin temperature triggers gasping, hypertension, and hyperventilation.

Various physiological or molecular disturbances that impair ENDOPLASMIC RETICULUM function. It triggers many responses, including UNFOLDED PROTEIN RESPONSE, which may lead to APOPTOSIS; and AUTOPHAGY.

A process fundamental to muscle physiology whereby an electrical stimulus or action potential triggers a myocyte to depolarize and contract. This mechanical muscle contraction response is regulated by entry of calcium ions into the cell.

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