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Xanthelasma - Biotech, Pharma and Life Science Channel

17:51 EST 14th December 2017 | BioPortfolio

Xanthelasma (or xanthelasma palpebrarum) is a sharply demarcated yellowish collection of cholesterol underneath the skin, usually on or around the eyelids. Although not harmful or painful, these minor growths may be disfiguring and can be removed. They are common in people of Asian origin and those from the Mediterranean region.

Because of the hereditary component, they may or may not indicate high blood levels of cholesterol. Where there is no family history of xanthelasmata, they usually indicate high cholesterol and may correlate with a risk of atheromatous disease.

A xanthelasma may instead be referred to as a xanthoma when becoming larger and nodular, assuming tumorous proportions. Still, xanthelasma is often classified simply as a subtype of xanthoma.

Xanthelasmata can be removed with a trichloroacetic acid peel, surgery, lasers or cryotherapy. Removal can cause scarring and pigment changes, but it is unusual after treatment with trichloroacetic acid.

Source; Wikipedia

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PubMed Articles [4 Associated PubMed Articles listed on BioPortfolio]

Effect of a high-cholesterol diet on lipoprotein metabolism and xanthoma formation in rabbits.

Xanthelasma is the most common type of cutaneous xanthoma and often occurs on the eyelids. Xanthoma has been reported to be highly correlated with abnormal lipoprotein metabolism.

The clinical spectrum of xanthomatous lesions of the eyelids.

Yellowish papules, nodules, or plaques, namely "xanthomatous" lesions, may be seen on the eyelids in the course of various disorders. The prototype is "xanthelasma palpebrarum" (XP) that is localized ...

Influence of Low Level Laser on Pain and Inflammation in Type 2 Diabetes Mellitus with Diabetic Dermopathy- A Case Report.

Numerous skin lesions have been commonly observed in individuals with diabetes mellitus. The common skin manifestations of diabetes mellitus are erythrsma, xanthosmatosis, xanthelasma, pycomycetes, an...

The clinical spectrum of Erdheim-Chester disease: an observational cohort study.

Erdheim-Chester Disease (ECD) is a rare, potentially fatal, multi-organ myeloid neoplasm occurring mainly in adults. The diagnosis is established by clinical, radiologic, and histologic findings; ECD ...

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