Clinical Research Organization Research

21:43 EDT 19th August 2018 | BioPortfolio

Antioxidant and antibacterial activity of silver nanoparticles synthesized by Cestrum nocturnum.

Silver nanoparticles are toxic to bacteria and have widespread application in different research areas.

Oocytes from stem cells.

Folliculogenesis describes the process of activating an oocyte-containing primordial follicle from the ovarian reserve and its development to the mature ovulatory stage. This process is highly complex and is controlled by extra- and intra-ovarian signaling events. Oocyte competence and capacity for fertilization to support a viable pregnancy are acquired during folliculogenesis. Cancer and cancer...

Most GP trainees intend to work less than full time, survey shows.

Oral steroids fail to prevent hearing loss in children with otitis media with effusion, shows trial.

Commentary: does the selective inversion approach demonstrate bias in the results of studies using routinely collected data?

What readers thought about a research paper's approach to compare treatment effects on mortality.

Brazil's child and maternal mortality have increased against background of public spending cuts.

Focusing on overdiagnosis as a driver of too much medicine.

Doctors are given go ahead to extract sperm from unconscious man in legal first.

E-cigarettes: relax rules to help more smokers quit, say MPs.

Correction notice to paper "Agreement of treatment effects for mortality from routinely collected data and subsequent randomized trials: meta-epidemiological survey".

Veterinary trials and tribulations.

Dog owner Jodi Ware makes the case for transparency in companion animal research.

Promoting scientist-advocate collaborations in cancer research: why and how.

Advocates bring unique and important viewpoints to the cancer research process, ensuring that scientific and medical advances are patient-centered and relevant. In this article, we discuss the benefits of engaging advocates in cancer research and underscore ways in which both the scientific and patient communities can facilitate this mutually beneficial collaboration. We discuss how to establish a...

The Effects of Cholesterol-Derived Oncometabolites on Nuclear Receptor Function in Cancer.

Epidemiologic studies are controversial concerning the roles played by cholesterol in cancer risk and development, possibly as it is not cholesterol per se that is pathologic in cancers. Indeed, recent data reveal that the cholesterol metabolism in cancer cells can generate endogenous oncopromoter metabolites at higher levels compared with normal tissues and/or can be deregulated in the production...

Does Racial Bias Affect NCI-Funded PIs' Willingness to Mentor Prospective Graduate Students?

Audit studies suggest that racial discrimination disadvantages black individuals in educational/professional advancement. We hypothesized that prospective black male doctoral students would experience greater disparity in responses when seeking access to National Cancer Institute (NCI)-funded principal investigators (PI) compared with prospective white males. Primary aim was to explore response an...

Automatic hyoid bone detection in fluoroscopic images using deep learning.

The displacement of the hyoid bone is one of the key components evaluated in the swallow study, as its motion during swallowing is related to overall swallowing integrity. In daily research settings, experts visually detect the hyoid bone in the video frames and manually plot hyoid bone position frame by frame. This study aims to develop an automatic method to localize the location of the hyoid bo...

Limited success with clostridium collagenase histolyticum following FDA approval for the treatment of Peyronie's disease.

Collagenase clostridium histolyticum (CCH) was approved for the treatment of Peyronie's disease (PD) in December of 2013. Recently, further research has supported its use. The aim of this study was to objectively evaluate the effects of CCH on penile curvature associated with Peyronie's disease at our high volume institution. Since the approval of CCH for PD, 45 men have undergone between 1 and 4 ...

Early detection of microvascular dysfunction in hypertension: the holy grail of cardiovascular prevention and risk assessment?

Physicians' experiences, attitudes and challenges in a Pediatric Telemedicine Service.

Telemedicine in general, and telephone triage, in particular, is considered a high-stress clinical activity and involves decision making under conditions of uncertainty and urgency.

Reading as Statistical Learning.

The purpose of this tutorial is to explain how learning to read can be thought of as learning statistical regularities and to demonstrate why this is relevant for theory, modeling, and practice. This tutorial also shows how triangulation of methods and cross-linguistic research can be used to gain insight.

Statistical Learning and Spelling.

The purpose of this article is to provide a tutorial on statistical learning and its role in learning to spell and to discuss the implications of the research for educators.

Learning Without Trying: The Clinical Relevance of Statistical Learning.

Statistical learning research seeks to identify the means by which learners, with little perceived effort, acquire the complexities of language. In the past 50 years, numerous studies have uncovered powerful learning mechanisms that allow for learning within minutes of exposure to novel language input.

Statistical Learning and Bilingualism.

Over the last 2 decades, research on statistical learning has demonstrated its importance in supporting language development. Notably, most of the research to date has focused on monolingual populations (or has not reported the language background of participants). Several recent studies, however, have begun to focus on the impact of bilingualism on statistical learning. To date, the results have ...

Do intoxicated witnesses produce poor facial composite images?

The effect of alcohol intoxication on witness memory and performance has been the subject of research for some time, however, whether intoxication affects facial composite construction has not been investigated.

Enhancing research for undergraduates through a nanotechnology training program that utilizes analytical and bioanalytical tools.

Nanotechnology is a broad field combining traditional scientific disciplines; however, analytical chemistry plays an important role in material design, synthesis, characterization, and application. This article emphasizes the uniqueness of nanotechnology and the importance of providing high-quality undergraduate research experiences to both attract and retain talented individuals to the field of n...

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