Colorectal Cancer

15:53 EDT 24th August 2019 | BioPortfolio

Colon or Colorectal cancer is the growth of malignant polyps on the colon, bowel, anus and rectum. Growths in these locations can be benign, and removed by colonoscopy, but they have a risk of becoming malignant. 

About 10 per cent of bowel cancer cases are strongly connected to hereditary conditions. Lynch syndrome, a hereditary non-polyposis colon cancer, is the most common hereditary colorectal cancer. Familial Adenomatous Polyposis, which usually causes the formation of many benign polyps in the large intestine, is a genetic disease that may predispose to bowel cancer. Ulcerative colitis or Crohn's disease of the colon, cause chronic irritation in the lining of the bowel, and these patients have a significantly higher chance to get bowel cancer.

Treatment option depend on the stage of the disease.  Standard treatment is surgery (the most common), chemotherapy and radiation therapy. New types of treatment are being tested in clinical trials. These include targeted therapy, where drugs or other substances identify and attack specific cancer cells without harming normal cells, for example Monoclonal antibody therapy.

Source; Adapted from National Cancer Institute

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