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endpoint Company Profile

11:30 EST 12th December 2018 | BioPortfolio

Endpoint provides clients with high-quality, authoritative advice on the clinical development of medicines. Endpoint's clients include multinational pharmaceutical companies, emerging biomedical ventures, biotechnology investment firms, contract research organizations, regulatory agencies and national health services.
Endpoint was started in London by Kenneth Klein, MD, a Harvard-trained physician who is board-certified in both internal medicine and gastroenterology. After a career in academic medicine Dr. Klein worked for 15 years in the pharmaceutical industry, holding various management positions with companies in the United States and Europe. He has helped bring major products from Phase I through regulatory approval and marketing. For example, for four years he was Global Project Leader for the anti-migraine drug zolmitriptan, now marketed as Zomig. In this position he led all aspects of the drug's worldwide development. This included primary responsibility for the design and implementation of the clinical trial program and coordination of the basic science, manufacturing, regulatory and commercial strategies.

Contact

Email: kbk@PrimaryEndpoint.com


News Articles [261 Associated News Articles listed on BioPortfolio]

ICON Enhances Endpoint Adjudication Services

Will leverage AG Mednet's comprehensive electronic endpoint adjudication system

A New Endpoint in Prostate Cancer: Metastasis-Free Survival

With overall survival considered an impractical endpoint because survival is so long, metastasis-free survival has emerged as a new endpoint in prostate cancer trials. Medscape Medical News

Novartis’ brolucizumab meets primary endpoint in phase III nAMD trial

Brolucizumab met its primary endpoint of non-inferiority versus aflibercept in best corrected visual acuity (BCVA) and exhibited superiority in key retinal outcomes at year one (48 weeks). Secondary ...

IGEL Positioned to Capitalize on Fast-Growing Demand for Linux at the Endpoint

SAN FRANCISCO, Aug. 27, 2018 /PRNewswire/ -- IGEL, a world leader in endpoint management software for the secure enterprise, today announced findings from the new Read more...

Vascepa® (icosapent ethyl) 26% Reduction in Key Secondary Composite Endpoint of Cardiovascular Death, Heart Attacks and Stroke Demonstrated in REDUCE-IT™ Supports 25% Overall Reduction in Five-Point Major Adverse Cardiovascular Event Primary Composit

Landmark Cardiovascular Risk Reduction Benefits Demonstrated in REDUCE-IT Are Largest of Any Major Cardiovascular Outcomes Study of a Drug Intended to Address Residual Cardiovascular Risk Remaining A...

EMA Consults On Endpoint For Faster Multiple Myeloma Drug Approvals

There is convincing data available on the use of negative minimal residual disease (MRD) as an intermediate endpoint, as long...    

Stallergenes Greer Announces That the Phase III Trial for Its Sublingual Allergy Immunotherapy Tablet STAGR320 to Treat House Dust Mite-Induced Allergic Rhinitis Achieved Its Primary Endpoint

The study achieved its primary efficacy endpoint (p<0.0001) The study also achieved all key secondary endpoints, and showed a comparable safety profil...

PFS Valid Surrogate Endpoint for Overall Survival in Frontline DLBCL

Progression-free survival appears to be a surrogate endpoint for overall survival in patients undergoing firstline treatment for diffuse large B-cell lymphoma, according to results from a large pooled...

Drugs and Medications [38 Associated Drugs and Medications listed on BioPortfolio]

Perindopril erbumine [Aurobindo Pharma Limited]

These highlights do not include all the information needed to use perindopril erbumine safely and effectively. See full prescribing information for perindopril erbumine tablets.Perindopril Erbumine Ta...

Losartan potassium [Qualitest Pharmaceuticals]

LOSARTAN POTASSIUM TABLETS USP R only

Losartan potassium [Endo Pharmaceuticals Inc. DBA Endo Generic Products]

Losartan Potassium Tablets USP R only

Leflunomide [NorthStar RxLLC]

Leflunomide Tablets USP

Renagel [Genzyme Corporation]

These highlights do not include all the information needed to use Renagel safely and effectively. See full prescribing information for Renagel. Renagel (sevelamer hydrochloride) Tablet for Oral use In...

PubMed Articles [116 Associated PubMed Articles listed on BioPortfolio]

Validation of the incremental shuttle walk test as a clinical endpoint in bronchiectasis.

There is a need for a validated clinical endpoint to assess response to therapies in bronchiectasis.

Extrapolation of in vitro structural alerts for mutagenicity to the in vivo endpoint.

As part of the hazard and risk assessment of chemicals in man, it is important to assess the ability of a chemical to induce mutations in vivo. Because of the commonalities in the molecular initiating...

Phase II trial design with growth modulation index as the primary endpoint.

Molecularly targeted, genomic-driven, and immunotherapy-based clinical trials continue to be advanced for the treatment of relapse or refractory cancer patients, where the growth modulation index (GMI...

Assessment of the Impact of an Endpoint Committee in the Ocular Hypertension Treatment Study.

To assess the impact of a masked Endpoint Committee on estimates of the incidence of primary open angle glaucoma (POAG), treatment efficacy and statistical power of the Ocular Hypertension Treatment S...

Lymphocyte Depletion and Risk of Acute Rejection in Renal Transplant Recipients at Increased Risk for Delayed Graft Function.

Delayed graft function (DGF) is a risk factor for acute rejection (AR) in renal transplant recipients and KDIGO guidelines suggest use of lymphocyte depletion induction when DGF is anticipated. We ana...

Clinical Trials [1178 Associated Clinical Trials listed on BioPortfolio]

A Clinical Trial Comparing Efficacy and Safety of Dabigatran Etexilate With Warfarin in Patients With Cerebral Venous and Dural Sinus Thrombosis (RE-SPECT CVT)

This is a multi-center, prospective, international, randomized (1:1), open-label study with two parallel groups. This phase III study is planned to investigate the efficacy and safety of d...

Repeatability and Reproducibility of Skin Test Endpoint Titration

This study will examine the within-tester repeatability and between-tester reproducibility of skin test endpoint titrations performed in those with allergic sensitivities.

Risk Accessment Model for Ischemic Stroke Endpoint Events

The present study aims to develope a risk accessment model of ischemic stroke endpoint events combining multi-dimensional TCM indicators with modern medicine indicators. The proposed study...

The WEB®-IT China Clinical Study

This trial is a prospective, multicenter, single-arm Objective Performance Criteria controlled confirmatory study. It is for evaluating safety and effectiveness of the WEB Aneurysm Emboliz...

To Compare the Efficacy of the Addition of Methotrexate (MTX) to Current Standard Acute Graft-versus-host Disease (GVHD) First-line Treatment With Corticosteroids

Phase III randomized double-blinded trial designed to compare the efficacy of the addition of MTX to current standard acute GVHD first-line treatment with corticosteroids. The protocol wil...

Companies [26 Associated Companies listed on BioPortfolio]

EndPoint Technologies

EndPoint Technologies is dedicated to providing comprehensive technology and business consulting services to life science organizations. Specializing in Medical Affairs in pharmac...

Endpoint Research

Endpoint Research is a full service Clinical Research Organization founded in 1990. We provide Phase I/II to IV clinical development services to pharmaceutical, biotechnology and medical device compan...

IGEL

IGEL delivers powerful unified endpoint management (UEM) software that is revolutionary in its simplicity and purpose-built for the enterprise. The company’s world-leading pr...

Valentis

Valentis is a biotechnology company that was engaged in the development of innovative products for peripheral arterial disease (PAD), a large and unsatisfied market. On July 11, 2006 Valentis announce...

endpoint

Endpoint provides clients with high-quality, authoritative advice on the clinical development of medicines. Endpoint's clients include multinational pharmaceutical companies, emerging biomedical ventu...

More Information about "endpoint" on BioPortfolio

We have published hundreds of endpoint news stories on BioPortfolio along with dozens of endpoint Clinical Trials and PubMed Articles about endpoint for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of endpoint Companies in our database. You can also find out about relevant endpoint Drugs and Medications on this site too.

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