Track topics on Twitter Track topics that are important to you
Intradigm is developing siRNA-derived cancer therapeutics utilizing its proprietary RNAi technology. Intradigm has led the advancement of siRNA from the test tube to a potent, tissue-targeted, systemically active therapeutic class of gene specific inhibitors. The Company believes that it is the first to demonstrate consistent and reproducible siRNA activity in animal disease models through targeted formulations of siRNA for systemic administration. Based upon the Company’s unique technology and capabilities for developing systemic tissue targeted formulations of siRNA and its ability to achieve efficacy in clinically relevant animal disease models, Intradigm has established an impressive cancer therapeutic product development program with its lead product, ICS-283, now in advanced pre-clinical development.
The Company’s initial focus is on siRNA inhibition of the VEGF pathway targeted to the angiogenic neovasculature. The siRNA formulated product can be used for the treatment of many serious diseases that result from excessive and unwanted angiogenesis, such as colon cancer, lung cancer and many other solid tumors as well as other angiogenesis based diseases such as ocular neovascularization. Intradigm has utilized its proprietary TargeTranÔ technology to develop siRNA formulations which can be systemically delivered and specifically targeted to neovasculature. This targeted, specific sequence siRNA, utilizing innovative layered nanoparticle technology, has been successfully evaluated in several angiogenesis disease animal models with demonstrated efficacy. Intradigm has identified colon cancer as the first indication to evaluate for its systemically administered VEGF pathway siRNA and expects to file an IND within the next 12 months.
In addition to its therapeutic product focus, Intradigm has taken advantage of its portfolio of in vivo siRNA technologies to establish a target validation service business to
12115 Parklawn Drive, Suite K
United States of America
Fax: (301)984-0186 (301)984-0186
IRVINE, Calif., Nov. 10, 2017 (GLOBE NEWSWIRE) -- CombiMatrix Corporation (NASDAQ:CBMX) ("CombiMatrix" or the "Company"), a family health molecular diagnostics company specializing in DNA-based r...
IRVINE, Calif., Nov. 02, 2017 (GLOBE NEWSWIRE) -- CombiMatrix Corporation (NASDAQ:CBMX) ("CombiMatrix" or the "Company"), a family health molecular diagnostics company specializing in DNA-based r...
IRVINE, Calif., Nov. 01, 2017 (GLOBE NEWSWIRE) -- CombiMatrix Corporation (NASDAQ:CBMX) ("CombiMatrix" or the "Company"), a family health molecular diagnostics company specializing in DNA-based r...
ORION CORPORATION MANAGERS' TRANSACTIONS 1st of November 2017 at 22.15 EET Orion Corporation: Managers' transactions - Hilpi Rautelin Orion Cor...
LAVAL, QUEBEC -- (Marketwired) -- 07/07/17 -- Savaria Corporation (TSX: SIS) ("Savaria" or the "Corporation"), one of North America's leaders in the accessibility industry, is pleased to announce th...
TORONTO, ONTARIO -- (Marketwired) -- 08/16/17 -- Ventripoint Diagnostics Ltd. ("Ventripoint" or the "Corporation") (TSX VENTURE: VPT) announces that at its Annual General Meeting on August 14, 2017 ...
EAST RUTHERFORD, N.J., Nov. 03, 2017 (GLOBE NEWSWIRE) -- Cambrex Corporation (NYSE:CBM), a leading manufacturer of small molecule innovator and generic Active Pharmaceutical Ingredients (APIs), t...
MENLO PARK, Calif., Nov. 01, 2017 (GLOBE NEWSWIRE) -- Geron Corporation (Nasdaq:GERN) today reported financial results for the three and nine months ended September 30, 2017. For the third ...
Intradigm is developing siRNA-derived cancer therapeutics utilizing its proprietary RNAi technology. Intradigm has led the advancement of siRNA from the test tube to a potent, tissue-targeted, system...
Toshiba Medical Systems Corporation is a leading worldwide provider of medical diagnostic imaging systems and comprehensive medical solutions, such as CT, X-ray and vascular, ultr...
Bruker Corporation is a leading provider of high-performance scientific instruments and solutions for molecular and materials research, as well as for industrial and applied analy...
NEC Corporation of America (NEC) is a leading technology integrator providing solutions that improve the way people work and communicate. NEC delivers integrated Solutions for Soc...
Hot Spring Spas is the worldâs leading brand of hot tubs and is sold through a network of more than 700 independent dealers throughout North America and 70 countries around t...
We have published hundreds of Intradigm Corporation news stories on BioPortfolio along with dozens of Intradigm Corporation Clinical Trials and PubMed Articles about Intradigm Corporation for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Intradigm Corporation Companies in our database. You can also find out about relevant Intradigm Corporation Drugs and Medications on this site too.
Head and neck cancers
Cancer can occur in any of the tissues or organs in the head and neck. There are over 30 different places that cancer can develop in the head and neck area. Mouth cancers (oral cancers) - Mouth cancer can develop on the lip, the tongue, the floor...