Expression Pathology Inc. Company Profile

20:58 EST 19th November 2017 | BioPortfolio

Pioneering microproteomics in formalin fixed paraffin embedded tissue, Expression Pathology’s business addresses a major bottleneck and unmet need in drug and life science research. With a focus on tissue analysis and protein biomarker discovery, EPI has developed the only technology available that makes possible discovery of proteins in archived tissue.Working with archived tissue is the key. Human and animal tissue, collected at surgery, biopsy or autopsy, has been preserved in formalin for over a century. Collections of such specimens with associated clinical information are available throughout medical research. However, up to now it has been difficult or impossible to undertake protein discovery and high throughput analysis in such archived tissue by existing methods. Yet these tissue collections are treasure troves for the discovery of relationships between proteins and documented clinical outcomes, such as disease progression, drug response and toxicity. EPI’s Liquid Tissue® Protein Prep Kit enables discovery and validation of new protein biomarkers from this tissue. EPI has developed and filed patents around a portfolio of new technologies that have been validated by prestigious research organizations, like the National Cancer Institute, that enable for the first time extraction and analysis of proteins from archived tissue by accurate, instrumented means, such as mass spectrometry and immunodetection.


9290 Gaither Road
United States of America


Phone: 1.301.977.3654

News Articles [542 Associated News Articles listed on BioPortfolio]

New 'pathology atlas' maps genes in cancer to accelerate progress in personalised medicine

A new 'Pathology Atlas' is launched today with an analysis of all human genes in all major cancers showing the consequence of their corresponding protein levels for overall patient survival. The diff...

New Pathology Atlas maps genes in cancer to accelerate progress in personalized medicine

A new Pathology Atlas is launched today with an analysis of all human genes in all major cancers showing the consequence of their corresponding protein levels for overall patient survival. The differe...

Integration and Interoperability Are Essential for Growth of Digital Pathology

Now that digital pathology has been approved for primary diagnosis of surgical pathology specimens (see: FDA Approves the Philips Digital Pathology WSI Solution for Primary Diagnosis), pathology depar...

New Pathology Atlas Contains All Cancer Genes to Show Way to Personalised Cancer Treatment

Swedish National Supercomputer Uses Big Data Approach To Show How Cancer Begins And Develops A new Pathology Atlas is launched today with an analysis of all human genes in all major cancers showing th...

The Changing Concepts in Pathology

Pathology as defined by Welch is “the science, as distinguished from the practice, of medicine. In a narrower and more restricted sense pathology is a study of the structural alterations produced by...

Pathology access and advocacy

Dr Fleming speaks with ecancer at the RSM meeting on cancer control about his work in the National Cancer Institute, and his history with developing pathology resources globally. He emphasises the ...

Proscia introduces new concept to transform pathology labs, drive digital evolution

Proscia Inc., a software solutions provider for digital pathology, announced today the introduction of its new concept: Software as a Lab. Proscia’s President and CEO David West will outline how the...

Digital Pathology And Deep Learning Set To Provide Prognostic Tools To Pathologists

Clinical Informatics News Contributed Commentary | Whole slide images is the latest offering from digital pathology to pathology departments and translational research centers with the hope of amassin...

Drugs and Medications [18 Associated Drugs and Medications listed on BioPortfolio]

Expression [Zenith Medicosm SL]

Drug Facts

Expression [Zenith Medicosm SL]

Drug Facts

Esika [Ventura Corporation LTD.]


Retin-a micro [Ortho-McNeil Pharmaceuticals]

RETIN-A MICRO® (tretinoin gel) microsphere, 0.1% and 0.04%

Retin-a micro [Physicians Total Care, Inc.]

RETIN-A MICRO® (tretinoin gel) microsphere, 0.1% and 0.04%

PubMed Articles [3405 Associated PubMed Articles listed on BioPortfolio]

Exercise training ameliorates matrix metalloproteinases 2 and 9 messenger RNA expression and mitigates adverse left ventricular remodeling in streptozotocin-induced diabetic rats.

The aim was to investigate whether exercise training (ExT) would ameliorate expression of key genes for myocardial morphostructure and mitigate adverse left ventricular (LV) remodeling in experimental...

The prognostic value of B7-H6 protein expression in human oral squamous cell carcinoma.

To investigate the expression and prognostic value of B7-H6 protein in oral squamous cell carcinoma tissues.

TDP-43 suppresses tau expression via promoting its mRNA instability.

In the brains of individuals with Alzheimer's disease (AD) and chronic traumatic encephalopathy, tau pathology is accompanied usually by intracellular aggregation of transactive response DNA-binding p...

Pathology Imagebase - A Reference Image Database for Standardization of Pathology.

Despite efforts to standardize histopathology practice through the development of guidelines, the interpretation of morphology is still hampered by subjectivity. We here describe Pathology Imagebase, ...

microRNA 183 family profiles in pheochromocytomas are related to clinical parameters and SDHB expression.

This study aims to examine the expression profiles of the miR-183 cluster (miR-96/182/183) in pheochromocytoma. Pheochromocytoma tissues were prospectively collected from 50 patients with pheochromocy...

Clinical Trials [1855 Associated Clinical Trials listed on BioPortfolio]

Feasibility of Opportunistic Salpingectomy at the Time of Vaginal Hysterectomy for Benign Pathology

In this prospective study, patients who underwent vaginal hysterectomy with salpingectomy or salpingo-oophorectomy were included. The objective of this study is to assess the feasibility o...

Optimizing the Strategy for Preoperative Chemotherapy in Locally Advanced Gastric/Gastroesophageal Cancer

This is a ramdomized,phase II,open-label study, The purpose of this study is to determine the optimal treatment for patients with locally advanced Gastric/Gastroesophageal Cancer according...

Shortystrap Effectiveness in the Treatment of the Pathology Pubic and Abdominal Pathology in Athletes

The pubic and abdominal pathology is common among athletes. It leads to a shutdown of physical activity for several months, and requires rehabilitative care, or surgery for a permanent cur...

Pivotal Study for Validation of Philips Dx

The primary objective of this study is to show safety and effectiveness of the PDx for IVD use as an aid to the pathologist to view, review and diagnose digital images of surgical patholog...

Relationship Between Abnormalities of Desmin Cytoskeleton, Mitochondrial Activity and Expression of Ubiquitin in Aspect of Pathogenesis of Heart Failure and Prognosis

The purpose of this study is evaluation of expression of desmin in cardiomyocytes of patients with idiopathic dilated cardiomyopathy. Analysis of relationship between desmin expression and...

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American Lab Staffing is a pathology search firm dedicated to hospitals, laboratories and practices that simply cannot afford to wait for staffing needs. We offer global job postings and cost effecti...

Lakewood Pathology Associates

Lakewood Pathology Associates (LPA) is a national anatomical pathology company providing comprehensive and dynamic pathology services tailored to the outpatient needs of surgeons of diverse specialtie...

HistoRx, Inc

HistoRx is a bioscience company applying quantitative tools of molecular and cellular biology to develop new tools for pathology.HistoRx has introduced the first tissue-based quantitative molecular as...

Mikroscan Technologies, Inc.

Mikroscan develops a range of distributed telepathology solutions for clinical, teaching, and research applications for anatomic pathology. Mikroscan products offer unprecedented ...

LifeSpan Biosciences

LifeSpan is the industry leader in molecular pathology. LifeSpan sells antibodies, immunohistochemistry services and localization databases. Founded in 1995, LifeSpan has developed proprietary antibod...

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Pharmacy is the science and technique of preparing as well as dispensing drugs and medicines. It is a health profession that links health sciences with chemical sciences and aims to ensure the safe and effective use of pharmaceutical drugs. The scope of...

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Clinical Approvals Clinical Trials Drug Approvals Drug Delivery Drug Discovery Generics Drugs Prescription Drugs In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which drugs are dis...

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