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We have established R&D collaborations with Shire, Takeda, AstraZeneca, Medimmune, and Novartis Option Fund, and have raised $40 million in venture financing from MVM Life Science Partners, Clarus Ventures, Novartis Venture Fund and Takeda Ventures.
Heptares is an industry pioneer in GPCR structure-based drug design and has built a unique capability for discovering novel molecules that modulate historically undruggable or challenging GPCRs. Our integrated discovery platform includes proprietary technologies for engineering stabilised GPCRs in their natural pharmacological conformations, identifying previously unknown chemistries for GPCR protein-drug interactions, and deploying advanced fragment-based approaches to GPCR target space for the first time.
Using this approach, we are generating a broad pipeline of drug candidates for serious CNS and metabolic disorders, including Alzheimer’s disease, Parkinson’s disease, schizophrenia, autism, anxiety & depression, chronic insomnia, addiction and diabetes.
Heptares was founded in 2007 to develop and commercialise pioneering research from the MRC Laboratory of Molecular Biology (Cambridge, UK) and the National Institute of Medical Research (London, UK). Heptares retains exclusive consultancies and active collaboration with MRC LMB and has rights to all IP generated from LMB relating to the application of the technology to GPCRs and other transmembrane proteins.
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Heptares Therapeutics agreed to collaborate with PeptiDream to identify, develop and market drugs that target G protein-coupl -More-
London, UK-based Heptares Therapeutics says the first healthy subject has now been dosed with its first-in-class, selective muscarinic M4 receptor agonist HTL0016878 in a Phase I clinical study.
Heptares Therapeutics, a wholly-owned subsidiary of Sosei Group, has launched a new research collaboration…
Heptares Therapeutics, the wholly-owned subsidiary of Sosei Group Corporation, announces the launch of a new research collaboration under its ORBIT initiative with Juntendo University in Tokyo, Japan....
Heptares Therapeutics, a wholly-owned subsidiary of Sosei Group, announced the launch of a new research collaboration under its ORBIT initiative with Juntendo University in Tokyo, Japan. The new coll...
Heptares Therapeutics and PeptiDream established a strategic collaboration to discover, develop and commercialize therapeutics targeting a jointly selected, undisclosed G protein-coupled receptor (GPC...
Heptares Therapeutics announces the launch of a new research collaboration under its ORBIT initiative with New York University (NYU) School of Medicine. This new collaboration will support a multi-yea...
UK-based Heptares Therapeutics has started dosing subjects in a Phase I clinical trial of HTL0016878 being developed for the treatment of neurobehavioural symptoms in Alzheimer’s disease patients.
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Heptares discovers and develops new medicines targeting GPCRs (G-protein-coupled receptors), a super-family of drug targets linked to a wide range of human diseases. We have established R&D co...
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We have published hundreds of Heptares Therapeutics Ltd news stories on BioPortfolio along with dozens of Heptares Therapeutics Ltd Clinical Trials and PubMed Articles about Heptares Therapeutics Ltd for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Heptares Therapeutics Ltd Companies in our database. You can also find out about relevant Heptares Therapeutics Ltd Drugs and Medications on this site too.
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