Axial Biotech, Inc. Company Profile

14:03 EST 18th December 2018 | BioPortfolio

sAxial Biotech, Inc. is focused on the use of genetics and the development of minimally invasive, motion preserving implants to advance the diagnosis and treatment of diseases and deformities of the human spine. Axial is the first company to pursue DNA-based pre-symptomatic and prognostic tests for common spinal conditions which will augment current clinical and surgical practices. In its initial product development initiative, Axial has made significant progress towards the discovery of a location in the human genome that is associated with adolescent idiopathic scoliosis. In addition, Axial’s founders have developed five fusionless surgical devices (including the only such device currently being implanted in humans) that have the promise of expanding the current treatable scoliosis patient population by a factor of ten. Axial intends to use its proprietary genetic intellectual property in the development of bio-mechanical devices, and to apply its gene discovery/product development methodology to other spinal diseases. Spine care has historically focused on ameliorating the pain and/or fixing structural damage after it occurs. Recent technological advances in minimally invasive surgical techniques and better instrumentation have made the spine industry the hottest segment of the medical device market today, according to Start-Up magazine. Market analysis indicates a $3 billion sales potential for new instrumentation alone within 4 years, with this market compounding at greater than 20% per year. In the last 24 months, over $250 million of reported venture capital financing has flowed into spine start-ups and investors have achieved exits totaling over $1 billion, including one IPO (NuVasive). Axial’s novel tests will complement the advances in surgical instrumentation by providing the spine care industry with the first to market diagnostic and prognostic tests for targeting earlier and more appropriate therapeutic interventions. Axial’s surgical devices, one of which is currently in off-label use in humans, represent the only available alternative to spine fusion in the treatment of scoliosis. Axial is located in Salt Lake City, Utah, a place the New York Times recently called “an ideal genetic laboratory.” (NYT, July 31, 2004 , page 1 )


2749 E. Parley’s Way, Suite 210
Salt Lake City
United States of America


Phone: 801-478-1650
Fax: 801-487-2477

News Articles [1617 Associated News Articles listed on BioPortfolio]

[Comment] Discontinuing tumour necrosis factor inhibitors in non-radiographic axial spondyloarthritis

Patients with axial spondyloarthritis are classified according to the 2009 Assessment of SpondyloArthritis international Society classification criteria—which are the basis for the differentiation b...

ACR: Ixekizumab Tops Placebo in Axial Spondyloarthritis

MONDAY, Oct. 22, 2018 -- For patients with active radiographic axial spondyloarthritis (r-axSpA) and prior inadequate response or intolerance to one or two tumor necrosis factor inhibitors (TNFi), ixe...

Neuropathic Pain Component in Axial Spondyloarthritis

In what ways might the neuropathic pain component impact quality of life and patient-reported outcomes in axial spondyloarthritis? Journal of Clinical Rheumatology

A single determination of C-reactive protein does not suffice to declare a patient with a diagnosis of axial spondyloarthritis ‘CRP-negative’

To be eligible to receive treatment with an anti-tumour necrosis factor (TNF), non-radiographic axial spondyloarthritis (nr-axSpA) patients require either elevated levels of C-reactive protein (CRP) (...

Cortical bone loss is an early feature of nonradiographic axial spondyloarthritis

In the present study, we investigated bone geometry, microstructure, and volumetric bone mineral density (vBMD) in a cohort of patients with nonradiographic axial spondyloarthritis (nr-axSpA) in order...

Widespread pain in axial spondyloarthritis: clinical importance and gender differences

There is a remarkable lack of detailed knowledge on pain areas in axial spondyloarthritis (axSpA), and their clinical relevance is largely unknown. Pain area may reflect local disease processes, but a...

Adalimumab May Help Maintain Remission in Non-Radiographic Axial Spondyloarthritis

In patients with active non-radiographic axial spondyloarthritis (nr-axSpA) who achieved remission while taking adalimumab, researchers saw fewer flares among those who continued taking the drug than ...

The prevalence of depression in axial spondyloarthritis and its association with disease activity: a systematic review and meta-analysis

Depression is common among patients with axial spondyloarthritis (axSpA), but reports of its prevalence are highly variable. We performed a systematic review to (i) describe the prevalence of depressi...

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PubMed Articles [241 Associated PubMed Articles listed on BioPortfolio]

Preparation of Carbodiimides with One-Handed Axial Chirality.

The axial chirality of carbodiimide was proposed in 1932, but the synthesis of carbodiimide with one-handed axial chirality has not been achieved because of the low barrier of racemization. This work ...

Axial disease in psoriatic arthritis and ankylosing spondylitis: a critical comparison.

Ankylosing spondylitis (AS) was first identified in the late 17th century. 250 years later, inflammatory spine disease was recognized to be one of the patterns of psoriatic arthritis (PsA). Isolated s...

Dual axial gradient-doping (Zr and Sn) on hematite for promoting charge separation in photoelectrochemical water splitting.

One of the crucial challenges to enhance the photoelectrochemical water splitting performance of hematite (α-Fe2O3) is to resolve its ultrafast charge recombination in bulk. Herein, we firstly descri...

Tracing the Pathway from Drift-Wave Turbulence with Broken Symmetry to the Production of Sheared Axial Mean Flow.

This study traces the emergence of sheared axial flow from collisional drift-wave turbulence with broken symmetry in a linear plasma device-the controlled shear decorrelation experiment. As the densit...

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Clinical Trials [204 Associated Clinical Trials listed on BioPortfolio]

Study of the Efficacy and Safety of Secukinumab in Patients With Active Psoriatic Arthritis With Axial Skeleton Involvement

The purpose of this study is to demonstrate the efficacy and safety of secukinumab 150 mg or 300 mg in the management of axial manifestations in PsA patients who have failed to respond to ...

Study of Adalimumab in Subjects With Axial Spondyloarthritis

This study will study how well adalimumab works in the short and long term in people with axial spondyloarthritis who are not diagnosed as having either ankylosing spondylitis or psoriatic...

Treat to Target Trial in Axial Spondylo Arthritis : The TICOSPA (Tight Control in Spondyloarthritis)

This is a not interventional, pragmatic, prospective, randomized (cluster) study to evaluate the potential benefit of a Treat to Target approach in comparison to routine treatment (i.e. us...

Efficacy and Safety of Namilumab for Moderate-to-severe Axial Spondyloarthritis

The study will assess the effect of namilumab, a GM-CSF inhibitor, on the clinical response in subjects with axial spondyloarthritis. Subjects will receive treatment with either namilumab ...

A Study of KHK4827 in Subjects With Axial Spondyloarthritis (axSpA)

To evaluate the efficacy of KHK4827 in axSpA (ankylosing spondylitis [AS] and non-radiographic axial spondyloarthritis [nr-axSpA]) subjects compared to placebo, as measured by the proporti...

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Axial Biotech, Inc.

sAxial Biotech, Inc. is focused on the use of genetics and the development of minimally invasive, motion preserving implants to advance the diagnosis and treatment of diseases and deformities of the h...

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We have published hundreds of Axial Biotech, Inc. news stories on BioPortfolio along with dozens of Axial Biotech, Inc. Clinical Trials and PubMed Articles about Axial Biotech, Inc. for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Axial Biotech, Inc. Companies in our database. You can also find out about relevant Axial Biotech, Inc. Drugs and Medications on this site too.

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Biotechnology - Biotech
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