Axial Biotech, Inc. Company Profile

09:41 EDT 21st September 2018 | BioPortfolio

sAxial Biotech, Inc. is focused on the use of genetics and the development of minimally invasive, motion preserving implants to advance the diagnosis and treatment of diseases and deformities of the human spine. Axial is the first company to pursue DNA-based pre-symptomatic and prognostic tests for common spinal conditions which will augment current clinical and surgical practices. In its initial product development initiative, Axial has made significant progress towards the discovery of a location in the human genome that is associated with adolescent idiopathic scoliosis. In addition, Axial’s founders have developed five fusionless surgical devices (including the only such device currently being implanted in humans) that have the promise of expanding the current treatable scoliosis patient population by a factor of ten. Axial intends to use its proprietary genetic intellectual property in the development of bio-mechanical devices, and to apply its gene discovery/product development methodology to other spinal diseases. Spine care has historically focused on ameliorating the pain and/or fixing structural damage after it occurs. Recent technological advances in minimally invasive surgical techniques and better instrumentation have made the spine industry the hottest segment of the medical device market today, according to Start-Up magazine. Market analysis indicates a $3 billion sales potential for new instrumentation alone within 4 years, with this market compounding at greater than 20% per year. In the last 24 months, over $250 million of reported venture capital financing has flowed into spine start-ups and investors have achieved exits totaling over $1 billion, including one IPO (NuVasive). Axial’s novel tests will complement the advances in surgical instrumentation by providing the spine care industry with the first to market diagnostic and prognostic tests for targeting earlier and more appropriate therapeutic interventions. Axial’s surgical devices, one of which is currently in off-label use in humans, represent the only available alternative to spine fusion in the treatment of scoliosis. Axial is located in Salt Lake City, Utah, a place the New York Times recently called “an ideal genetic laboratory.” (NYT, July 31, 2004 , page 1 )


2749 E. Parley’s Way, Suite 210
Salt Lake City
United States of America


Phone: 801-478-1650
Fax: 801-487-2477

News Articles [1863 Associated News Articles listed on BioPortfolio]

[Comment] Discontinuing tumour necrosis factor inhibitors in non-radiographic axial spondyloarthritis

Patients with axial spondyloarthritis are classified according to the 2009 Assessment of SpondyloArthritis international Society classification criteria—which are the basis for the differentiation b...

Axial reports findings of elevated 4-EPS in children with ASD

(MacDougall Biomedical Communications, Inc.) Axial Biotherapeutics today announced that Srinivas Rao, M.D., Ph.D., Axial's Chief Medical Officer, will present new data from Axial's research of the lin...

Axial involvement develops within 5 years of juvenile spondyloarthritis diagnosis

Although children diagnosed with juvenile spondyloarthritis demonstrate a low rate of symptomatic activity at onset, there is a marked increase in axial involvement in most patients after 5 years, acc...

Depression high among patients with axial SpA, linked to impairment

Depression prevalence is high among patients with axial spondyloarthritis, and is associated disease activity, functional impairment, lower income and lack of exercise, according to findings published...

Unilateral DBS Reduces Axial Essential Tremor

With greater potential for side effects associated with bilateral deep-brain stimulation, does starting with a unilateral procedure make sense for treating axial essential tremor? Medscape Medical N...

Anti-CD74 IgA level insufficient for axial spondyloarthritis diagnosis before age 45 years

The evaluation of anti-CD74 IgA antibodies is not specific enough to provide a significant benchmark for the diagnosis of axial spondyloarthritis in patients younger than 45 years who present with ear...

A single determination of C-reactive protein does not suffice to declare a patient with a diagnosis of axial spondyloarthritis ‘CRP-negative’

To be eligible to receive treatment with an anti-tumour necrosis factor (TNF), non-radiographic axial spondyloarthritis (nr-axSpA) patients require either elevated levels of C-reactive protein (CRP) (...

Long-term Humira sustains improvements in axial spondyloarthritis

Désirée van der HeijdeAmong patients with nonradiographic axial spondyloarthritis, treatment with adalimumab provided sustained remission, with long-term clinical and functional improvements maintai...

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PubMed Articles [271 Associated PubMed Articles listed on BioPortfolio]

Effectiveness of a Referral Program for rheumatoid arthritis and axial spondyloarthritis Diagnosis at Primary Care Centers in Portugal - SIARA STUDY.

Early diagnosis and treatment of Rheumatoid Arthritis (RA) and axial Spondylarthritis (axial SpA) can limit the impact of disease outcomes. This study evaluated the effectiveness of a referral program...

Axial disease in psoriatic arthritis and ankylosing spondylitis: a critical comparison.

Ankylosing spondylitis (AS) was first identified in the late 17th century. 250 years later, inflammatory spine disease was recognized to be one of the patterns of psoriatic arthritis (PsA). Isolated s...

Dual axial gradient-doping (Zr and Sn) on hematite for promoting charge separation in photoelectrochemical water splitting.

One of the crucial challenges to enhance the photoelectrochemical water splitting performance of hematite (α-Fe2O3) is to resolve its ultrafast charge recombination in bulk. Herein, we firstly descri...

Tracing the Pathway from Drift-Wave Turbulence with Broken Symmetry to the Production of Sheared Axial Mean Flow.

This study traces the emergence of sheared axial flow from collisional drift-wave turbulence with broken symmetry in a linear plasma device-the controlled shear decorrelation experiment. As the densit...

Second-quarter biotech job picture.

Clinical Trials [195 Associated Clinical Trials listed on BioPortfolio]

Study of the Efficacy and Safety of Secukinumab in Patients With Active Psoriatic Arthritis With Axial Skeleton Involvement

The purpose of this study is to demonstrate the efficacy and safety of secukinumab 150 mg or 300 mg in the management of axial manifestations in PsA patients who have failed to respond to ...

Study of Adalimumab in Subjects With Axial Spondyloarthritis

This study will study how well adalimumab works in the short and long term in people with axial spondyloarthritis who are not diagnosed as having either ankylosing spondylitis or psoriatic...

Treat to Target Trial in Axial Spondylo Arthritis : The TICOSPA (Tight Control in Spondyloarthritis)

This is a not interventional, pragmatic, prospective, randomized (cluster) study to evaluate the potential benefit of a Treat to Target approach in comparison to routine treatment (i.e. us...

Efficacy and Safety of Namilumab for Moderate-to-severe Axial Spondyloarthritis

The study will assess the effect of namilumab, a GM-CSF inhibitor, on the clinical response in subjects with axial spondyloarthritis. Subjects will receive treatment with either namilumab ...

A Study of KHK4827 in Subjects With Axial Spondyloarthritis (axSpA)

To evaluate the efficacy of KHK4827 in axSpA (ankylosing spondylitis [AS] and non-radiographic axial spondyloarthritis [nr-axSpA]) subjects compared to placebo, as measured by the proporti...

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Axial Exchange, Inc. supports our national journey from fee-based to performance-based healthcare. The company’s products, Axial Provider and Axial Patient, enable con...

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Axial Biotherapeutics

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Axial Biotech, Inc.

sAxial Biotech, Inc. is focused on the use of genetics and the development of minimally invasive, motion preserving implants to advance the diagnosis and treatment of diseases and deformities of the h...

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