Axial Biotech, Inc. Company Profile

23:27 EDT 20th March 2018 | BioPortfolio

sAxial Biotech, Inc. is focused on the use of genetics and the development of minimally invasive, motion preserving implants to advance the diagnosis and treatment of diseases and deformities of the human spine. Axial is the first company to pursue DNA-based pre-symptomatic and prognostic tests for common spinal conditions which will augment current clinical and surgical practices. In its initial product development initiative, Axial has made significant progress towards the discovery of a location in the human genome that is associated with adolescent idiopathic scoliosis. In addition, Axial’s founders have developed five fusionless surgical devices (including the only such device currently being implanted in humans) that have the promise of expanding the current treatable scoliosis patient population by a factor of ten. Axial intends to use its proprietary genetic intellectual property in the development of bio-mechanical devices, and to apply its gene discovery/product development methodology to other spinal diseases. Spine care has historically focused on ameliorating the pain and/or fixing structural damage after it occurs. Recent technological advances in minimally invasive surgical techniques and better instrumentation have made the spine industry the hottest segment of the medical device market today, according to Start-Up magazine. Market analysis indicates a $3 billion sales potential for new instrumentation alone within 4 years, with this market compounding at greater than 20% per year. In the last 24 months, over $250 million of reported venture capital financing has flowed into spine start-ups and investors have achieved exits totaling over $1 billion, including one IPO (NuVasive). Axial’s novel tests will complement the advances in surgical instrumentation by providing the spine care industry with the first to market diagnostic and prognostic tests for targeting earlier and more appropriate therapeutic interventions. Axial’s surgical devices, one of which is currently in off-label use in humans, represent the only available alternative to spine fusion in the treatment of scoliosis. Axial is located in Salt Lake City, Utah, a place the New York Times recently called “an ideal genetic laboratory.” (NYT, July 31, 2004 , page 1 )


2749 E. Parley’s Way, Suite 210
Salt Lake City
United States of America


Phone: 801-478-1650
Fax: 801-487-2477

News Articles [1802 Associated News Articles listed on BioPortfolio]

PsA scoring systems showed moderate sensitivity, high specificity in detecting change

The quantifying of radiographic axial psoriatic arthritis through currently available scoring systems has moderate sensitivity but high specificity for identifying true change, according to results.Re...

Nonradiographic axial spondyloarthritis: clinical and therapeutic relevance

Current classification criteria for axial spondyloarthritis (axSpA) provide for the inclusion of patients with a wide range of presentations and manifestations. While not considered a formal subclassi...

Ankylosing spondylitis, non radiographic axial spondyloarthritis carry similar disease burden

Patients with ankylosing spondylitis and nonradiographic axial spondyloarthritis share comparable disease burden and treatment patterns in clinical practice, according findings published in Arthritis ...

Obesity worsens physical function, QoL in axial spondyloarthropathy

SAN DIEGO — Patients with both obesity and axial spondyloarthropathy have higher disease activity, worse physical function and lower quality of life, according to data from a press release issued at...

Anti-CD74 IgA level insufficient for axial spondyloarthritis diagnosis before age 45 years

The evaluation of anti-CD74 IgA antibodies is not specific enough to provide a significant benchmark for the diagnosis of axial spondyloarthritis in patients younger than 45 years who present with ear...

Certolizumab pegol decreased spinal, sacroiliac inflammation in axial spondyloarthritis

Patients with axial spondyloarthritis who received treatment with certolizumab pegol exhibited rapid decreases in spinal and sacroiliac-joint inflammation as observed using MRI throughout a 4-year, ph...

Global and Chinese Axial Radial Seal Industry, 2017 Market Research Report [Report Updated: 17122017] Prices from USD $3000

The 'Global and Chinese Axial Radial Seal Industry, 20122022 Market Research Report' is a professional and indepth study on the current state of the global Axial Radial Seal industry with a focus on t...

Guest commentary: Obesity has ‘complex’ effect on disease outcomes in axial spondyloarthropathy

Vivian P. BykerkIn this guest commentary, Vivian P. Bykerk, BSc, MD, FRCPC, discusses the relationship between obesity and disease outcomes in axial spondyloarthropathy following a presentation on the...

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PubMed Articles [281 Associated PubMed Articles listed on BioPortfolio]

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The global area of biotech crops in 2016 increased from 179.7 million hectares to 185.1 million hectares, a 3% increase equivalent to 5.4 million hectares. Some 26 countries planted biotech crops, 19 ...


Axial myopia is associated with elongation of the posterior ocular segment. The authors measured posterior fundus landmarks and assessed their associations with axial length.

Experimental Demonstration of a Sizeable Nonclassical CH···G Hydrogen Bond in Cyclohexane Derivatives: Stabilization of an Axial Cyano Group.

Base-catalyzed equilibration of anancomeric cyanocyclohexanes demonstrates that replacement of cis-3,5-dimethyl holding groups with electron-withdrawing CF3 groups dramatically increases the proportio...

Effectiveness of a Referral Program for rheumatoid arthritis and axial spondyloarthritis Diagnosis at Primary Care Centers in Portugal - SIARA STUDY.

Early diagnosis and treatment of Rheumatoid Arthritis (RA) and axial Spondylarthritis (axial SpA) can limit the impact of disease outcomes. This study evaluated the effectiveness of a referral program...

Fibromyalgia is not axial spondyloarthritis: Towards an appropriate use of the ASAS classification criteria for axial SpA.

Clinical Trials [168 Associated Clinical Trials listed on BioPortfolio]

Study of the Efficacy and Safety of Secukinumab in Patients With Active Psoriatic Arthritis With Axial Skeleton Involvement

The purpose of this study is to demonstrate the efficacy and safety of secukinumab 150 mg or 300 mg in the management of axial manifestations in PsA patients who have failed to respond to ...

Study of Adalimumab in Subjects With Axial Spondyloarthritis

This study will study how well adalimumab works in the short and long term in people with axial spondyloarthritis who are not diagnosed as having either ankylosing spondylitis or psoriatic...

Treat to Target Trial in Axial Spondylo Arthritis : The TICOSPA (Tight Control in Spondyloarthritis)

This is a not interventional, pragmatic, prospective, randomized (cluster) study to evaluate the potential benefit of a Treat to Target approach in comparison to routine treatment (i.e. us...

A Study of KHK4827 in Subjects With Axial Spondyloarthritis (axSpA)

To evaluate the efficacy of KHK4827 in axSpA (ankylosing spondylitis [AS] and non-radiographic axial spondyloarthritis [nr-axSpA]) subjects compared to placebo, as measured by the proporti...

Certolizumab Pegol in Subjects With Active Axial Spondyloarthritis

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