ACTIVATE Company Profile

06:49 EDT 24th June 2018 | BioPortfolio

News Articles [71 Associated News Articles listed on BioPortfolio]

Agios starts Activate trial for pyruvate kinase deficiency

Agios Pharmaceuticals has started the Activate trial, a Phase lll study analysing the efficacy and safety of AG-348 for the...Read More... The post Agios starts Activate trial for pyruvate kinase defi...

How opioid drugs activate receptors

Researchers found that opioid drugs and the brain’s natural opioids activate nerve cell receptors differently.

Cold can activate body's 'good' fat at a cellular level, study finds

(University of Nottingham) Lower temperatures can activate the body's 'good' fat formation at a cellular level, a new study led by academics at The University of Nottingham has found.

Let K-Ras activate its own inhibitor

Blocking LSD1 could activate cancer immune response via HERV

Oocyte DNA damage quality control requires consecutive interplay of CHK2 and CK1 to activate p63

Agios Announces Initiation of Global Phase 3 Trial (ACTIVATE) of AG-348 in Adults with Pyruvate Kinase Deficiency Who Are Not Regularly Transfused

CAMBRIDGE, Mass., June 18, 2018 (GLOBE NEWSWIRE) -- Agios Pharmaceuticals, Inc. (NASDAQ:AGIO), a leader in the field of cellular metabolism to treat cancer and rare genetic diseases, today announce...

How Your Brain Remembers What You Had for Dinner Last Night

UC San Diego researchers find small sets of hippocampal neurons activate for each episodic memory

Drugs and Medications [6 Associated Drugs and Medications listed on BioPortfolio]

Little ouchies little remedies pain relief [Medtech Products Inc.]

Little Ouchies Little Remedies Pain Relief

3m avagard foam [3M Health Care]

Avagard™ Foam Instant Hand Antiseptic With Moisturizers

Babor stop cellulite [Babor Cosmetics America, Corp]

Stop Cellulite Fluid insert

Prolia [Amgen Inc]

These highlights do not include all the information needed to use Prolia safely and effectively. See full prescribing information for Prolia. Prolia (denosumab)Injection, for subcutaneous use Initial ...

Methylphenidate hydrochloride [Mallinckrodt Inc.]


PubMed Articles [148 Associated PubMed Articles listed on BioPortfolio]

Phosphorylated EGFR Dimers Are Not Sufficient to Activate Ras.

Growth factor binding to EGFR drives conformational changes that promote homodimerization and transphosphorylation, followed by adaptor recruitment, oligomerization, and signaling through Ras. Whether...

Pathogen- and Danger-Associated Molecular Patterns and the Cytokine Response in Sepsis.

The sepsis syndrome is a systemic host inflammatory response accompanied by organ dysfunction in response to invading microbial pathogens. The host recognizes both danger and pathogens through its pat...

Chronic social isolation in adaptation of HPA axis to heterotypic stress.

Social crowding and isolation are recognized as major stressors and risk factors for development of psychiatric disorders. Chronic isolation stress (IS) and crowding stress (CS) activate neuroendocrin...

Fc gamma receptors are expressed in the developing rat brain and activate downstream signaling molecules upon cross-linking with immune complex.

Exposure of the developing brain to immune mediators, including antibodies, is postulated to increase risk for neurodevelopmental disorders and neurodegenerative disease. It has been suggested that im...

A novel dimeric dipeptide mimetic of the BDNF selectively activates the MAPK-Erk signaling pathway.

On the basis of the structure of beta-turn of loop 2 of brain-derived neurotrophic factor (BDNF), its new dimeric dipeptide mimetic bis-(N-hexanoyl-L-seryl-L-lysine) hexamethylenediamide (GTS-201) was...

Clinical Trials [179 Associated Clinical Trials listed on BioPortfolio]

ACTIVATE: A Computerized Training Program for Children With ADHD

A preliminary clinical trial of ACTIVATE will be conducted in a sample of children with ADHD. ACTIVATE is a computerized neurocognitive training program (ACTIVATE; see:

Unravelling Effectiveness of a Nurse-led Behavior Change Intervention to Enhance Physical Activity in Patients

A two-armed, cluster randomized controlled trial will be conducted comparing the Activate intervention with care as usual in 26 general practices in the Netherlands, in which approximately...

Individualized Precise Localization of rTMS on Primary Motor Area

Parkinson's disease (PD) patients have some problem with self-initiated movement task. Compared with health controls, task meta-analysis found that PD patients showed abnormal activation i...

Individualized Precise Localization of rTMS on Precentral and Parietal Gyrus

Attention deficit hyperactivity disorder (ADHD) patients have some problem with sustained attention. The dorsal anterior cingulate cortex (dACC) plays a key role for attention control. It ...

CD133 Transplantation to Generate Oocytes in Poor Ovarian Reserve

Women delay maternity and, as a consequence, available oocyte number and their quality decrease (9-18% of all IVF patients). Different treatment protocols have been developped nevertheless...

Companies [48 Associated Companies listed on BioPortfolio]


ACTIVATE offers a collection of innovative, nutrient-enhanced water beverages in a range of varieties free of sugar, calories and preservatives that makes it easy and convenient f...


RaNA Therapeutics, Inc.

RaNA Therapeutics is pioneering the discovery of a new class of medicines that target RNA to selectively activate protein expression within the body’s own cells. RaNA’s ...

RxIBR for Health Arising™

The pivotal guiding scientific principle for Health Arising 2003 is that of Targeted Biologic Therapy™. Each of the RxIBR developed pharmaceutical biologicals (animal origin) and/or botanicals (pla...


RevGenetics is focused on providing and developing the highest quality science-based small molecule supplements for the general public. Its products are designed to activate specific genes, resulting ...

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