A&G Pharmaceutical Incorporated Company Profile

11:50 EST 23rd November 2017 | BioPortfolio

A&G Pharmaceutical, Inc. (A&G) was incorporated in Delaware on June 6, 2000, as a "C" Corporation, to make use of two proprietary technologies that are unique to the Company. A&G is located in Baltimore, Maryland, and consists of two distinct but integrate divisions: 1) the Pharmaceutical Division and 2) the Monoclonal Antibody Services Division.

Pharmaceutical Division

Breast cancer is the most common and most fatal malignancy for women worldwide. Overall, 15 percent of women will be diagnosed with breast cancer during their lifetime. Although breast cancer may initially be hormone-dependent and treated with anti-estrogen therapy such as tamoxifen, metastatic breast cancer will recur in 50 percent of patients within 5 years of initial treatment. The survival rate of women receiving chemotherapy is 10 to 20 percent after 5 years.

The first FDA-approved biological therapy for metastatic breast cancer, Genentech's Herceptin, was launched very successfully in 1998. Herceptin, the first antibody-based cancer therapy, is a humanized monoclonal antibody that represses erbB2. It is used as a therapeutic agent to treat patients with metastatic breast cancer over-expressing erbB2, which constitutes only 20 percent of all metastatic breast cancers. Currently, there is no similar clinical treatment for breast cancer patients not over-expressing erbB2.

Recently, A&G co-founder Dr. Ginette Serrero has cloned the novel growth factor PCDGF that is over-expressed in all metastatic breast cancers. It has been shown that inhibiting PCDGF expression or action leads to a 98 percent inhibition of human breast tumor formation in experimental animals. A&G has successfully obtained the exclusive patent rights to develop both diagnostic tools and therapeutic agents using monoclonal anti-PCDGF antibodies to address the market need for treating metastatic non-erbB2 breast cancers.

Monoclonal Antibody Services Division

A&G owns a proprietary technology that enables A&G to provide its customers the fastest monoclonal antibody production service in the industry (60 days versus an average of 180 days) and with the highest success rate (85 percent compared to an industry average of 25 percent). The Monoclonal Antibody Services Division is also developing monoclonal antibodies to key growth factors/receptors for licensing.


600E Lombard St., Suite 511
United States of America


Phone: 410-230-0901
Fax: 410-230-0903

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PubMed Articles [395 Associated PubMed Articles listed on BioPortfolio]

Pharmaceutical care for patients of the third age in pharmacy organizations as a significant aspect of social gerontology.

There are questions in the article that study mutual relations of patients of elderly and senile age with pharmaceutical experts. It was revealed that pharmacy organizations are an important element i...

Critical review of surface-enhanced Raman spectroscopy applications in the pharmaceutical field.

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Adventures in the Environmental World and Environmental Microbiology Sampling of Air for Pharmaceutical Sterile Compounding.

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Prioritization of diseases for the development of a pharmaceutical care service model in South Korea using the analytic hierarchy process

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Clinical Trials [271 Associated Clinical Trials listed on BioPortfolio]

Pharmaceutical Care for Asthma Control Improvement (PHARMACI)-Study

The objective of this study is to evaluate the therapeutic effectiveness and cost-effectivity of pharmaceutical care for asthma patients.

Pharmaceutical Care for Diabetes Type 2 Patients: a Randomised Controlled Trial

The objective of this study is to evaluate the therapeutic effectiveness and cost-effectivity of pharmaceutical care for diabetes type 2 patients. Patients will be randomly allocated to th...

Improving Compliance Among Elderly Polypharmacy Users Through Community Pharmacy Based Pharmaceutical Care Program

The aim of the project is to evaluate effectiveness of a multidimensional pharmaceutical care plan in improving compliance among elderly polypharmacy users at community pharmacy settings. ...

Impact of Collaborative Pharmaceutical Care on Hospital Admission Drug Prescriptions for Patients 65 Years of Age and Older

The primary objective of this study is to evaluate the impact of the implementation of collaborative pharmaceutical care on drug support at admission for patients 65 years of age and older...

Pharmaceutical Care Service in Diabetes

The purpose of this study is to examine the effectiveness of pharmaceutical care service in the management of poorly controlled type 2 diabetes mellitus.

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