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Discovery Laboratories Company Profile

23:52 EST 19th February 2020 | BioPortfolio

Discovery Laboratories, Inc. is a specialty pharmaceutical company leveraging its platform technology in humanized lung surfactants to develop novel respiratory therapies and pulmonary drug delivery products. Surfactants are produced naturally in the lungs and are essential to the lungs' ability to absorb oxygen.

Our humanized surfactant technology is being developed initially for critical care patients with life-threatening respiratory disorders where there are few or no approved therapies available. Surfaxin®, our lead product, is currently in Phase 3 clinical trials for Respiratory Distress Syndrome in premature infants (RDS), a Phase 3 clinical trial for Meconium Aspiration Syndrome in full-term infants (MAS), and a Phase 2 clinical trial for Acute Lung Injury/Acute Respiratory Distress Syndrome in adults (ALI/ARDS).



We are also developing aerosolized formulations of our humanized surfactant to treat respiratory conditions such as asthma and as a novel pulmonary drug delivery vehicle to render drugs more effective when delivered to or via the respiratory tract.



A lack of functional surfactant is associated with several severe respiratory diseases. Research has established that surfactant replacement is highly effective in treating RDS and holds great promise in treating MAS, ALI/ARDS, asthma and other respiratory disorders. However, RDS is the only respiratory disease being treated today with approved surfactants, which are principally animal derived. The current supply of these surfactants is limited and their manufacture is both inexact and expensive, making it difficult to develop these products to treat broader populations for RDS therapy or other respiratory diseases.



Because our products are based on an engineered humanized surfactant, they can be produced economically at scale, as a high quality pharmaceutical, without the risk of potential transmission of animal-borne diseases or adverse immunological reaction. Products from our technology platform have the potential to be superior to currently marketed surfactants, treat critical care respiratory conditions, and treat larger, ambulatory patient populations that could benefit from surfactant therapy or drug delivery.

Location

2600 Kelly Road, Suite 100
Warrington
PA
18976-3622
United States of America

Contact

Phone: 215.488.9300
Fax: 215.488.9301
Email: ir@discoverylabs.com


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