Applied Molecular Company Profile

01:07 EST 20th November 2017 | BioPortfolio

Applied Molecular Evolution, Inc. (AME) is a leader in the application of directed molecular evolution to improve healthcare by optimizing and developing human biotherapeutics. AME uses its proprietary AMEsystem™ directed molecular evolution technology platform to optimize genes and therapeutic proteins for specific commercial purposes. AME optimizes the full range of proteins, including antibodies, cytokines, hormones and enzymes to develop improved versions of currently marketed, FDA-approved biotherapeutics as well as novel human biopharmaceuticals.

AME has collaborations with leading developers of biotherapeutics including Centocor, Lilly, Chiron, MedImmune, Bristol-Myers Squibb, Seattle Genetics, Cell Matrix and Biosynexus, whose biopharmaceutical projects may benefit from significant optimization of therapeutic and commercial parameters including:

Improved safety, efficacy and potency

Enhanced convenience

Decreased manufacturing costs

Broadened and lengthened patents


3520 Dunhill Street
San Diego
United States of America


Phone: (858) 597-4990
Fax: (858) 597-4950

News Articles [645 Associated News Articles listed on BioPortfolio]

Scientists at the Foundation for Applied Molecular Evolution Awarded One of Eight Nationwide Transformative Research Awards - Totaling $3 million

Alachua, Florida (PRWEB) October 09, 2017 The National Institutes of Health announced today that one of eight Transformative Researc...

Applied BioMath, LLC to Present Poster on Quantitative Systems Pharmacology Modeling of ...

Applied BioMath's poster highlights how their quantitative systems pharmacology (QSP) approach provides biological insights into the impact of drug-to-antibody ratio and the resulting changes in mo...

Giving Molecular Combing the Golden Coat it Deserves

The novel spin given to some traditional and established technologies can be astounding. They might have been around for decades, applied in the same way over and over again, and yet, at some point, s...

AccuRef Diagnostics Emerges as a New Division of Applied StemCell, Inc. With a Focus on Advancing Molecular Diagnostics Through Precision Reference Standards

AccuRef Diagnostics (ARD) is announcing its formation as a new division under Applied StemCell, Inc., an ISO-certified global provider of molecular and cellular reference standard...

Securing the Supply Chain with Molecular Tagging

ArticleA Q&A with Bob Miglani of Applied DNA Sciences about how the company’s plant-based SigNature DNA technology can assist the pharmaceutical industry in meeting the requirements of DSCSA.

Study examines cross-species interactions

In a first-of-its-kind study, NC State researchers applied a new approach to examine how members of two different species – a plant and a pathogen, for example, or a bacterium and a human – intera...

Pro-Trader Daily: Earnings Review and Free Research Report: Applied Genetic Announced Q4 and Full Year FY17 Results

LONDON, UK / ACCESSWIRE / October 2, 2017 / Pro-Trader Daily has just published a free post-earnings coverage on Applied Genetic Technologies Corp. (NASDAQ: AGTC) ("Applied Genetic"), which can be ...

Giant molecular cages made for energy conversion and drug delivery

The porous, 'sponge'-type molecules have an enormous internal surface area. This allows their use as 'molecular flasks' or 'molecular containers' that change the reactivity and properties of encapsula...

Drugs and Medications [394 Associated Drugs and Medications listed on BioPortfolio]

Xolegel [Stiefel Laboratories Inc]


Sun savvy solar shield [APPLIED SKIN TECHNOLOGY LLC]


U40 [Kylemore Pharmaceuticals, LLC]

U40 Foam

Mometasone furoate ointment usp, 0.1% [E. FOUGERA and CO.]


Mometasone furoate [Physicians Total Care, Inc.]

PubMed Articles [1279 Associated PubMed Articles listed on BioPortfolio]

Controls, Fit-for-purpose Assays, Verification Versus Validation, and Tissue Tools for IHC: Announcing a Workshop From the International Society for Immunohistochemistry and Molecular Morphology, Held at the 12th Annual Retreat for Applied Immunohistochemistry and Molecular Morphology, February 4, 2018.

Acute Myeloid Leukemia (AML): Upregulation of BAALC/MN1/MLLT11/EVI1 Gene Cluster Relate With Poor Overall Survival and a Possible Linkage With Coexpression of MYC/BCL2 Proteins.

Molecular heterogeneity accounts for the variable and often poor prognosis in acute myeloid leukemia (AML). The current risk stratification strategy in clinical practice is limited to karyotyping and ...

Spectral clustering using Nyström approximation for the accurate identification of cancer molecular subtypes.

A major challenge in clinical cancer research is the identification of accurate molecular subtype. While unsupervised clustering methods have been applied for class discovery, this clustering method r...

Improved and Standardized Approaches to Selection of Control Materials From ISIMM: Announcing a Workshop at the Annual ASCP Meeting, September 6-7, 2017, Sponsored by the International Society for Immunohistochemistry and Molecular Morphology.

The Hierarchical Response of Human Corneal Collagen to Load.

Fibrillar collagen in the human cornea is integral to its function as a transparent lens of precise curvature, and its arrangement is now well-characterised in the literature. While there has been con...

Clinical Trials [2181 Associated Clinical Trials listed on BioPortfolio]

Pregnancy Outcome of Women Using Low Molecular Weight Heparin Before Frozen-thawed Embryo Transfer

Embryo freezing is a technique used commonly to optimize the pregnancy rate in assisted reproduction techniques (ART). Hormone replacement therapy (HRT) regimen is applied to prepare endom...

Study of Sperm Molecular Factors Implicated in Male Fertility

Sperm analysis following World Health Organization guidelines is unable to explain the molecular causes of male infertility when basic sperm parameters are within a normal range and women ...

The Application of Ticagrelor Combined With Low Molecular Weight Heparin During PCI

The purpose of this study is to determine ticagrelor combining with low molecular weight heparin is effective and safe during PCI or not.

In Vivo EGFR Molecular Classification

The investigators developed 18F-MPG as a targeted molecular imaging agent for noninvasive and repeatable detecting EGFR-activating mutational status.

Clinical Value of Molecular Genetic Analyzes in Gynecological Malignomas

The aim of the planned research project is to find out the clinical significance of molecular genetic analyzes in gynecological malignomas. In particular, it will be investigated how the k...

Companies [1208 Associated Companies listed on BioPortfolio]

Applied BioCode, Inc.

Applied BioCode, Inc. is a privately held biotechnology company with headquarters located in Santa Fe Springs, California. Applied BioCode develops, manufactures, and markets high...

Applied Molecular

Applied Molecular Evolution, Inc. (AME) is a leader in the application of directed molecular evolution to improve healthcare by optimizing and developing human biotherapeutics. AME uses its proprietar...

Applied Biosystems (Australia)

Applied Biosystems has demonstrated its position as a technology leader and driving force in the changing dynamics of the life science marketplace. The Applied Biosystems business is focused on the fo...

Applied Precision, Inc.

Applied Precision is a leading provider of innovative microscopy imaging, measurement and analysis systems for the life sciences industries and OEM markets. Headquartered in Issaquah, Washington, just...

Molecular Templates Inc.

Molecular Templates Inc. is creating an entirely new generation of potent anti-cancer agents based on proprietary applied proteomics technologies.The novel therapeutic agents in development by MTI are...

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