Collateral Therapeutics Incorporated Company Profile

10:48 EST 21st November 2017 | BioPortfolio

Collateral's initial non-surgical gene therapy products under investigation are designed to promote and enhance angiogenesis, a natural biological process which results in the growth of additional blood vessels, to increase levels of blood flow to oxygen-deprived tissues.

The Company's angiogenic products are administered using methods of gene therapy based on non-surgical adenoviral vector delivery of angiogenic genes. In addition to the Company's angiogenic product candidates, the Company is actively researching gene therapy products designed to increase responsiveness of the heart to adrenergic stimulation and to stimulate heart muscle regeneration.

The Company's lead product candidate, GENERX™ (Ad5-FGF4) is a non-surgical angiogenic gene therapy, which is being developed as a potential treatment for patients with stable exertional angina (chest pain) due to coronary artery disease (CAD).


11622 El Camino Real
San Diego
United States of America


Phone: 858.794.3400
Fax: 858.794.3440

News Articles [542 Associated News Articles listed on BioPortfolio]

ICE Threatens More 'Collateral' Arrests In Response To California 'Sanctuary' Law

SAN FRANCISCO ― The Trump administration will go after undocumented immigrants in their neighborhoods and at work in California, likely picking up “collateral” they were not initially targeting,...

Boost in collateral, not 'feeling richer,' drives consumers to borrow as home prices rise

(Princeton University, Woodrow Wilson School of Public and International Affairs) Boost in collateral rather than feeling richer drives borrowing as home prices rise, Princeton University economist fi...

Vical Incorporated Announces Pricing of $25 Million Underwritten Public Offering of Common Stock

SAN DIEGO, Nov. 08, 2017 (GLOBE NEWSWIRE) -- Vical Incorporated (Nasdaq:VICL) today announced the pricing of its underwritten public offering of 14,285,714 shares of common stock or common stock ...

Radiologic Factors Associated with Rapid Stroke Progression

For patients with radiologic evidence of poor collateral circulation, interventional treatment may be futile.

Concurrent with BMS acquisition, IFM Therapeutics spins off IFM Therapeutics LLC

Innate immunity-focused IFM Therapeutics is spinning off its non-oncology assets into the new company IFM Therapeutics LLC.

Deals this week: Nabriva Therapeutics, LifeMine Therapeutics, Aldeyra Therapeutics

Nabriva Therapeutics plans to raise $80m through an underwritten public offering of shares of its common stock.

Payment cap would ‘virtually eliminate’ the ability to conduct clinical trials

A proposed regulation in New Jersey demonstrates a lack of understanding regarding the clinical trial process and has clear collateral damage to research conduct in the state, ACRO testifies.

ProQR spins out Amylon Therapeutics for CNS therapeutics

ProQR Therapeutics has spun out Amylon Therapeutics, a privately-held company focused on the development of therapies for central nervous system (CNS) disorders, with seed funding from a group of inst...

PubMed Articles [513 Associated PubMed Articles listed on BioPortfolio]

Stroke etiology and collaterals: atheroembolic strokes have greater collateral recruitment than cardioembolic strokes.

Chronic hypoperfusion from athero-stenotic lesions is thought to lead to better collateral recruitment compared to cardioembolic strokes. It was sought to compare collateral flow in stroke patients wi...

Distinct predictive role of collateral status on clinical outcome in variant stroke subtypes of acute large arterial occlusion.

Clinical trials have showed that robust collateral flow has a relationship with good clinical outcome, however, different stroke subtypes were lumped together. This study explored the relationship bet...

The effectiveness of super-selective injection with anchor balloon technique for collateral channel assessment.

The careful assessment of collateral channels is important for a retrograde approach for a chronic total coronary occlusion (CTO). This case report describes a percutaneous coronary intervention for C...

Simultaneous combined complete tear of radial and ulnar collateral ligaments of thumb in an adolescent.

Isolated tear of collateral ligaments of thumb are common but combined injuries of both radial and ulnar collateral ligaments are rare. These cases are reported in athletes involved in high-impact spo...

Collateral artery pathways of the femoral and popliteal artery.

The role of collateral artery circulation in the lower limb is under debate but clinically relevant, particularly when using covered stents for occlusive disease. Covered stents seem to outperform nit...

Clinical Trials [169 Associated Clinical Trials listed on BioPortfolio]

Comparison of Coronary Wedge Pressure and Collateral Flow Index Between Main Branch and Side Branch Vessels

The purpose of this trial is to compare the degree of collateral flow in the main vessel and the side branch vessel. Specifically, the trial will address the superiority of the recruitable...

the Effects of Cerebral Collateral Circulation on the Outcome of Leukoaraiosis in High-risk Population

This study observed the relationship between cerebral collateral circulation and the prognosis of leukoaraiosis in high-risk population. Cerebral collateral circulation and leukoaraiosis l...

The Impact of NBP on the Collateral Circulation in ICA/M1 Occlusion

Stroke is the first leading cause of death in China, and is responsible for almost 22.4% of deaths. In approximately 80% of cases stroke is ischaemic, i.e. caused by disruption of blood fl...

MR-based Collateral Imaging to Predict Response to Endovascular Treatment of Stroke (FAST-COLL Study)

Based on the results of recent randomized controlled trials, current international guidelines recommend the initiation of endovascular treatment within 6 hours of symptom onset for acute i...

Ultrasound Study of Season-Long Joint Changes to College Baseball Players

The purpose of this study is to use ultrasound imaging to determine if there are certain frequencies, durations, and intensities of baseball pitching that expose a college baseball player ...

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Collateral Therapeutics Incorporated

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Gene Therapy
Gene therapy is the use of DNA as a pharmaceutical agent to treat disease. It derives its name from the idea that DNA can be used to supplement or alter genes within an individual's cells as a therapy to treat disease. The most common form of gene th...

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