Astex Technology Limited Company Profile

16:48 EST 19th November 2017 | BioPortfolio

Astex Technology is a structure-based drug discovery company pioneering the use of high throughput X-ray crystallography for the rapid identification of novel drug candidates. The company's unique structural screening approach utilizes protein crystal structures to detect the binding of drug fragments, which are then optimized into potent lead compounds. Facilitating this approach is the company's integrated drug discovery platform of HTX* technologies, which covers all aspects of structure-based research, including protein production, crystallization, structure determination, bioinformatics and computational and medicinal chemistry. Astex is focusing its drug discovery approaches on protein targets from families and/or pathways, including validated kinases, phosphatases and proteases implicated in human disease. Astex has two research agreements with Janssen Research Foundation, a division of Johnson & Johnson, and a cytochrome P450 structural biology research agreement with AstraZeneca AB.


250 Cambridge Science Park, Milton Road
United Kingdom


Phone: +44 (0) 1223 22 62 00
Fax: +44 (0) 1223 22 62 01

News Articles [56 Associated News Articles listed on BioPortfolio]

Astex Pharmaceuticals: James Manuso & Harren Jhoti introduce the newly formed Astex Pharmaceuticals

In this episode of PharmaTelevision News Review, Paul Larsmon talks to James Manuso Chairman & CEO and Harren Jhoti President of Astex Pharmaceuticals.

Astex Pharmaceuticals, Inc. Strategy, SWOT and Corporate Finance Report [Report Updated: 01082017] Prices from USD $175

Astex Pharmaceuticals, Inc. Strategy, SWOT and Corporate Finance ReportSummaryAstex Pharmaceuticals, Inc. Strategy, SWOT and Corporate Finance Report, is a source of comprehensive company data and i...

CR UK, Newcastle Uni extend alliance with Astex

Cancer Research UK and Newcastle University have extended their strategic drug discovery alliance with Astex Pharmaceuticals by three years to work on developing new cancer drugs and associated biomar...

Martin Buckland talks about the great potential created by the recent merger between SuperGen Inc. and Astex Therapeutics

In this episode of PharmaTelevision News Review, Fintan Walton talks to Martin Buckland, CBO of Astex Therapeutics

Cancer Research UK and NU agree three-year research Astex Pharma deal

Cancer Research UK and Newcastle University have announced that their existing research collaboration with Astex Pharmaceuticals will be extended for a further three years. The alliance was formed fiv...

InSysBio LLC announce renewal of agreement with ASTEX Pharmaceuticals Inc.

(Institute for Systems Biology Moscow) nSysBio LLC (, one of the pioneers in Quantitative Systems Pharmacology (QSP) modeling and simulation for drug development, announced today a ren...

Cancer Research UK and Newcastle University extend drug discovery partnership with Astex

Cancer Research UK and Newcastle University have extended their strategic drug discovery alliance with Astex Pharmaceuticals for three years.

InSysBio LLC Announce Renewal Of Agreement With Astex Pharma

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PubMed Articles [625 Associated PubMed Articles listed on BioPortfolio]

Astex shapes CDK4/6 inhibitor for approval.

Technology Games: Using Wittgenstein for Understanding and Evaluating Technology.

In the philosophy of technology after the empirical turn, little attention has been paid to language and its relation to technology. In this programmatic and explorative paper, it is proposed to use t...

Technology Interventions to Manage Food Intake: Where Are We Now?

This review describes the state-of-the-art for dietary assessment using smartphone apps and digital technology and provides an update on the efficacy of technology-mediated interventions for dietary c...

Ability to Resist Temptations of Technology Use: A Qualitative Analysis of Children's Views on Factors Associated with Delay of Gratification.

Excessive technology use among young children remains a public health concern with diverse serious consequences. It is important to find out how children resist the temptation to use technology. Using...

Subjective Technology Adaptivity Predicts Technology Use in Old Age.

To date, not much is known about the psychological and motivational factors underlying technology use in late life. What are the interindividual determinants that lead older adults to invest in using ...

Clinical Trials [1101 Associated Clinical Trials listed on BioPortfolio]

User Evaluation of the Peristomal Skin Condition in Ostomates Using ConvaTec Moldable Technology™

The primary aim of this study is to demonstrate the maintenance of healthy peri-stomal skin over a two month period in subjects who use ConvaTec Moldable Technology™ Skin Barriers as par...

Safety and Efficacy of Using GlucoSat Technology For Non-Invasive Glucose Measurement

This study is a prospective, open label, controlled, single center study. 40 patients will be recruited for the study, according to patients’ inflow and meeting eligibility criteria. Pr...

Endoleak Repair Guided by Navigation Technology

The study is aimed at investigating whether repair of endoleak type II can be improved by adding navigation technology. Can this technology increase precision by guiding the needle that pu...

Improving Outcomes Using Technology for Children Who Are DHH

This study evaluates the efficacy of using augmentative and alternative communication (AAC) technology for enhancing language development in children who are deaf or hard of hearing. Half ...

Use of Near Infrared Technology as a Guide in Laparoscopic Resection of Pancreatic Lesions: the COLPAN "Colour-and-resect" Project

The purpose of this study is to determine whether the use of Near-Infrared Technology can guide the laparoscopic resection of hypervascular neoplasms of the pancreas.

Companies [523 Associated Companies listed on BioPortfolio]

Astex Therapeutics

Astex was founded in 1999 by Harren Jhoti, PhD, former Head of Structural Biology and of UK Bioinformatics at GlaxoWellcome, together with Professor Sir Tom Blundell, FRS, Professor Chris Abell, (both...

Astex Technology Limited

Astex Technology is a structure-based drug discovery company pioneering the use of high throughput X-ray crystallography for the rapid identification of novel drug candidates. The company's unique st...

Astex Pharmaceuticals, Inc.

Astex Pharmaceuticals is dedicated to the discovery, development, and commercialization of novel therapeutics with a focus on cancer. The Company is developing a proprietary pipeline of novel cancer...

Microsulis Medical Limited

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Immunocore Limited

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