Biocept Incorporated Company Profile

23:28 EDT 20th March 2018 | BioPortfolio

Privately held Biocept was founded in 1997 and is based in Carlsbad, California near San Diego.

Biocept is emerging as a leader in the development and commercialization, in part through partners, of Next Generation Microarrays for Genomics and Proteomics™. Biocept’s proprietary platform technology is based on novel hydrogel polymers. The resulting three-dimensional microarrays have very high sensitivity, excellent precision and a broad dynamic range. Biocept has already developed several assay formats for the analysis of samples containing nucleic acids or proteins. Biocept has collaborations with investigators at leading research organizations for prototype microarrays to monitor the expression of apoptosis-related genes.

Life Sciences applications of Biocept’s genomic and proteomic microarrays include pharmaceutical research and development [e.g. target identification and validation, expression profiling, pathway analysis, high throughput screening, ADMET studies, and detection of single nucleotide polymorphisms (SNP's)] and clinical diagnostics.

Science & Technology:

Successful genomic and proteomic research requires tools that can rapidly and accurately provide results. While gene expression profiling is frequently the first step, protein expression may ultimately be more important, since proteins are the targets for most drugs. Gene expression does not always correlate well with the amount or activity of expressed proteins. In addition, protein diversity and activity results from alternative splicing at the messenger RNA level and by post-translational modifications such as phosphorylation and glycosylation. Several forms of a single protein may have important roles either as targets for drug discovery or as indicators of toxicity. These relationships demonstrate the crucial importance of proteomics in drug discovery.

Biocept's platform technology uses proprietary hydrogel polymers to create three-dimensional microarrays. Biocept prints microdroplets in an array on a treated glass slide. Each microdroplet contains a large number of molecules of a single probe, uniformly dispersed within and covalently bound to the hydrogel matrix. Key features of Biocept's microarrays are:

§ Versatile-useful for genomic and proteomic applications-

Biocept has developed and demonstrated the utility of genomic and proteomic microarrays in formats suitable for many life sciences applications.

§ High probe density provides high precision and broad dynamic range-

The higher probe density provides a lower coefficient of variation and broader dynamic range than conventional two-dimensional microarrays.

· Aqueous environment allows biomolecular probes to retain native conformation and activity-

Probes tethered within a hydrogel microdroplet retain their native three-dimensional configuration and activity, improving interaction with targets in the sample.

§ Readily manufactured-

Microdroplets about 300 microns in diameter and 30 microns thick are deposited as an array on a treated glass slide.

Biocept’s platform technology is protected by issued or pending patents in all major pharmaceutical markets.

Commercialization Strategy:

Biocept is establishing corporate partnerships and other collaborations to accelerate the development, commercialization and utilization of microarrays based on its technology. This includes partnerships with Pharmaceutical/Biotech companies for research and development, collaborations with Life Science Reagents companies, partnerships for clinical diagnostics, and partnerships to enhance technology development and commercialization.


2151 Las Palmas Drive, Suite C
United States of America


Phone: (760) 804-9580 x15
Fax: (760) 804-6238
Email: kbrown@biocept

News Articles [18 Associated News Articles listed on BioPortfolio]

Biocept, UC San Diego team up on PD-L1 detection study

Biocept and the University of California at San Diego reached a partnership to conduct a clinical validation study of the com -More- 

Biocept announces pricing of $15M public offering

A public offering of common stock and stock purchase warrants has been priced by Biocept at $0.45 in hopes of raising $15 mil -More- 

Public offering could bring in $3M for Biocept

A public offering of more than 4.9 million shares of common stock was priced by Biocept in hopes of raising $3 million.  -More- 

Best efforts public offering nets $13.7mm for Biocept

Molecular diagnostics firm Biocept Inc. closed a best efforts public offering, netting $13.7mm through the sale of 32.85mm common shares at $0.45. (The company originally filed to sell 33.33mm shares....

Biocept (BIOC) Presents At 30th Annual ROTH Conference - Slideshow

Biocept's (BIOC) CEO Michael Nall on Q3 2017 Results - Earnings Call Transcript

Vical Incorporated Announces Pricing of $25 Million Underwritten Public Offering of Common Stock

SAN DIEGO, Nov. 08, 2017 (GLOBE NEWSWIRE) -- Vical Incorporated (Nasdaq:VICL) today announced the pricing of its underwritten public offering of 14,285,714 shares of common stock or common stock ...

NVO Gets FDA Nod, GALT Down But Not Out, BIOC Gets A Boost, CUR Excited

Today's Daily Dose brings you news about Avastin getting full approval for the most aggressive form of brain cancer; FDA action date for Clovis' Rucaparib sNDA; InspireMD's 24-month follow-up results ...

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