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NEOKIMIA is a chemistry-based discovery company that integrates advanced synthesis and combinatorial chemistry capabilities with computational methods to produce libraries of novel, potentially bioactive molecules. The main component of the highly versatile, patented NEOKIMIA technology platform is the design and synthesis of conformationally defined, sophisticated macrocyclic molecules in a parallel fashion using (primarily) modern automated solid phase technologies. Appropriate recognition elements (small molecule building blocks, some of which are commercially available and others that are prepared internally) are assembled in a stepwise fashion together with a unique segment (a "tether" specially designed by NEOKIMIA) that restricts the molecule to specific spatial orientations. With the aid of computational techniques, the design of these macrocyclic libraries is based on consideration of diversity in terms of chemical composition, three-dimensional shape, and appropriate physical properties (Lipinski Rules of Five). To date, more than 35,000 macrocycles have been produced utilizing this proprietary approach. The versatility provided by this unique combination of diversity in terms of structure and conformation yields an extremely powerful discovery technique with applications in a wide variety of therapeutically relevant biological systems.
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SAN DIEGO, Nov. 08, 2017 (GLOBE NEWSWIRE) -- Vical Incorporated (Nasdaq:VICL) today announced the pricing of its underwritten public offering of 14,285,714 shares of common stock or common stock ...
NEOKIMIA is a chemistry-based discovery company that integrates advanced synthesis and combinatorial chemistry capabilities with computational methods to produce libraries of novel, potentially bioact...
PRAECIS PHARMACEUTICALS INCORPORATED is a biopharmaceutical company focused on the discovery and development of novel compounds to address unmet medical needs or improve existing therapies.PRAECIS has...
Founded in 2008 by the Axis Biotec Brasilâ¢ group (www.axisbiotec.com.br), PharmaPraxis has incorporated technologies, and will develop and launch biologic products in Brazil....
COOK SIS is sold under various brand names to treat a wide range of conditions including management of dermal wounds and burns, reinforcement of many types of weakened tissue, and treatment of urinary...
Founded by Conrad Kenley in 1990, LCG, Inc. is a leader in providing grants management solutions to health and social services agencies. LCG Systems (a subsidiary of LCG, Inc.) ...
We have published hundreds of NeoKimia Incorporated news stories on BioPortfolio along with dozens of NeoKimia Incorporated Clinical Trials and PubMed Articles about NeoKimia Incorporated for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of NeoKimia Incorporated Companies in our database. You can also find out about relevant NeoKimia Incorporated Drugs and Medications on this site too.
Clinical Approvals Clinical Trials Drug Approvals Drug Delivery Drug Discovery Generics Drugs Prescription Drugs In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which drugs are dis...
Biological therapy involves the use of living organisms, substances derived from living organisms, or laboratory-produced versions of such substances to treat disease. Some biological therapies for cancer use vaccines or bacteria to stimulate the body&rs...