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KuDOS Pharmaceuticals Limited Company Profile

20:10 EST 18th November 2017 | BioPortfolio

KuDOS Pharmaceuticals is a leader in the discovery and development of novel small molecule drugs that target DNA repair and related systems for the treatment f human diseases, in particular cancer. The company was founded by Professor Stephen Jackson of the Wellcome/Cancer Research UK Institute of the University of Cambridge, UK, an internationally renowned scientist in the field of DNA repair.

The company, including its subsidiary, ChemOvation Ltd currently employs 60 people.



KuDOS Pharmaceuticals has identified a number of naturally occurring DNA repair mechanisms and proteins that are fundamental to the control of cell growth and cell death. Whilst primarily focused on the discovery and development of novel therapeutic agents for use in cancer therapy, DNA repair inhibitors can also be used in the treatment of viral infections, ischaemia and immunosuppression.



Since May 1999, KuDOS Pharmaceuticals has established a strong scientific platform that has resulted in the identification of several new classes of promising drug candidates targeted at DNA repair enzymes for the treatment of cancer. KuDOS’ leading product, PaTrin-2, is planned to enter Phase II clinical trials in melanoma and colorectal cancer by 3-4Q 2002. AQ4N, a hypoxic cell cytotoxin, is currently in Phase I evaluation.



Other products are entering pre-clinical studies with the aim of initiating Phase I clinical trials by 2Q 2003/1Q 2004.



Each of KuDOS’ products is based on a detailed molecular understanding of tumour cells and will enhance efficacy of ionising radiation and major chemotherapy regimen.



Product portfolio:



PaTrin-2: Phase II commencing Q4 2002



AQ4N: Phase I ongoing



DNA-PK/ATM inhibitor: Pre-clinical development commencing Q2/3 2002



PARP inhibitor: Pre-clinical development commencing Q3/4 2002



KuDOS Pharmaceuticals has a range of products for development as cancer treatments and will take these forward to Phase II clinical trials prior to partnering products with major pharmaceutical companies for product approval and commercialisation. Applications for other than cancer treatment will be out-licensed at an earlier stage.

Location

327, Cambridge Science Park, Milton Road,
Cambridge
Cambridgeshire
CB4 0WG
United Kingdom

Contact

Phone: 01223 719719
Fax: 01223 719720
Email: jbward@kudospharma.co.uk


News Articles [475 Associated News Articles listed on BioPortfolio]

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Telix Pharmaceuticals Limited Successfully Completes $50 Million Oversubscribed Initial Public Offering

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Kevin McCann and Mark Nelson Appointed to the Board of Directors of Telix Pharmaceuticals Limited

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NJIT graduate student wins kudos for her research on a potent counterterrorism tool

(New Jersey Institute of Technology) At a meeting held by the U.S. Defense Threat Reduction Agency to review ongoing research on materials capable of defeating or disabling weapons such as anthrax, Ch...

Telix Pharmaceuticals Limited Launches $50 Million Underwritten Initial Public Offering (ASX: TLX)

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Appointment of Director

Oxford, UK, 1 November 2017: e-Therapeutics plc (AIM: ETX), a company pioneering the use of Network-Driven Drug Discovery (NDD) to create new and better drugs, announces the appointment of Christine...

Oncobiologics announces strategic partnership with GMS Tenshi Holdings Pte. Limited

CRANBURY, N.J., Sept. 08, 2017 (GLOBE NEWSWIRE) -- Oncobiologics, Inc. (NASDAQ:ONS) today announced that it entered into a Purchase Agreement on September 7, 2017 with GMS Tenshi Holdings Pte. Li...

PubMed Articles [121 Associated PubMed Articles listed on BioPortfolio]

Analysing researchers' outreach efforts and the association with publication metrics: A case study of Kudos.

With the growth of scholarly collaboration networks and social communication platforms, members of the scholarly community are experimenting with their approach to disseminating research outputs, in a...

Announcing the 2017 Pharmaceuticals Travel Award for Young Post-Doctoral Researchers.

Last year, for the first time in its history, our Journal was able to offer a travel grant of 800 CHF to a young researcher in the field of medicinal chemistry.

Suspended solids moderate the degradation and sorption of waste water-derived pharmaceuticals in estuarine waters.

This study focuses on the fate of pharmaceuticals discharged into an estuarine environment, particularly into the Turbidity Maximum Zone (TMZ). Batch experiments were set up to investigate the factors...

Chiral pharmaceuticals: A review on their environmental occurrence and fate processes.

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The synergistic impact of salts and organic matter on adsorption of ibuprofen and sulfamethoxazole by three types of biochar and an activated carbon was investigated using reclaimed water reverse osmo...

Clinical Trials [207 Associated Clinical Trials listed on BioPortfolio]

Kansas University DHA Outcome Study (KUDOS) Follow-Up

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Study Comparing Citalopram Hydrobromide Tablets 40 mg (Torrent Pharmaceuticals Ltd) and RLD Tablets 40 mg (Manufactured By Forest Pharmaceuticals Inc, Missouri) in 24+2 Normal Healthy Male Subjects in Fed Condition

- Objective: - The objective of this study is to compare the rate and extent of absorption of the Test Product, Citalopram Hydrobromide 40 mg (Torrent Pharmaceutical Li...

Bioequivalence Study of Torrent Pharmaceuticals Ltd.'s Rosuvastatin Calcium Tablets Under Fed Conditions

Subjects to compare the single dose bioavailability of Torrent's Rosuvastatin Calcium Tablets 40 mg and Crestor® 40 mg Tablets of AstraZeneca Pharmaceuticals LP, USA. Dosing periods of st...

Cilostazol 50 mg Tablets Under Fasting Conditions

This study will compare the relative bioavailability (rate and extent of absorption) of 50 mg Cilostazol Tablets manufactured by TEVA Pharmaceuticals Industries Ltd. and distributed by TEV...

Study Comparing Citalopram Hydrobromide Tablets 40 mg (Torrent Pharmaceuticals Ltd) and RLD Tablets 40 mg (Manufactured By Forest Pharmaceuticals Inc, Missouri) in 24+2 Normal Healthy Male Subjects Under Fasting Condition

- Objective: - To compare the rate and extent of absorption of Citalopram Hydrobromide Tablets 40 mg: Test Product: Citalopram Hydrobromide Tablets 40 mg manufactured b...

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