MethylGene Incorporated Company Profile

08:19 EST 11th December 2018 | BioPortfolio

MethylGene is engaged in the discovery and development of drugs for diseases for which there are currently limited or no treatments. Research on the Company's first target, the DNA Methyltransferase enzyme, has yielded a unique anti-cancer drug presently in Phase I clinical trials. Several other targets are being investigated, including HDAC (histone deacetylase) and ER-1 (early response gene) for cancer as well as ß-Lactamase for infectious diseases. With in vivo evidence of efficacy, discoveries have notably given rise to a novel class of small molecule ß-Lactamase inhibitor which may aid in the fight against antibiotic resistance; while on the cancer front, small molecule HDAC inhibitors are showing promise. With its solid biology and chemistry platforms, MethylGene is entering the 21st century with a dedication to improving people's health and quality of life.


7220 Frederick-Banting, Suite 200
H4S 2A1


Phone: 514 337 3333
Fax: 514 337 0550

News Articles [1 Associated News Articles listed on BioPortfolio]

CERESPIR INCORPORATED and the NATIONAL NEUROSCIENCE INSTITUTE SINGAPORE Announce Positive Data Showing Beneficial Effects of CERESPIR’s Clinical Stage Compound Itanapraced in a LRRK2 Model of Parkinson’s Disease 

Itanapraced blocks LRRK2 expression and LRRK2-mediated neurotoxicity Itanapraced ready to advance to Phase 2 in Parkinson’s disease patients with and without genetic mutation NEW YORK and SINGAPO...

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Companies [39 Associated Companies listed on BioPortfolio]

MethylGene Incorporated

MethylGene is engaged in the discovery and development of drugs for diseases for which there are currently limited or no treatments. Research on the Company's first target, the DNA Methyltransferase e...

MethylGene Inc.

MethylGene is a publicly-traded biopharmaceutical company listed on the Toronto Stock Exchange under the symbol MYG. We focus in the areas of cancer, infectious disease and other diseases such as diab...


PRAECIS PHARMACEUTICALS INCORPORATED is a biopharmaceutical company focused on the discovery and development of novel compounds to address unmet medical needs or improve existing therapies.PRAECIS has...


Founded in 2008 by the Axis Biotec Brasil™ group (, PharmaPraxis has incorporated technologies, and will develop and launch biologic products in Brazil....


COOK SIS is sold under various brand names to treat a wide range of conditions including management of dermal wounds and burns, reinforcement of many types of weakened tissue, and treatment of urinary...

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