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Bicycle Therapeutics Ltd. Company Profile

00:55 EDT 19th September 2018 | BioPortfolio

Bicycle Therapeutics is a biotechnology company developing a platform technology that enables the creation of a new generation of biotherapeutics which combine the desirable features of small molecules and biopharmaceuticals to create highly specific and highly stable drugs.

Applying phage selection techniques to repertoires of chemically constrained cyclic peptides allows the identification and optimisation of molecules with high target specificity and binding affinity that are also stable to unfolding and to the action of proteases. These peptides could be regarded as a mini-antibodies with covalent organic cores, and as such should overcome the weaknesses of previous generations of peptide based therapeutics.

Bicycle Therapeutics is a spin-out from the Medical Research Council Laboratory of Molecular Biology, Cambridge, based on the pioneering work of the founding scientists Sir Gregory Winter and Dr.Christian Heinis. Bicycle Therapeutics is managed by Dr. John Tite (Chief Executive Officer) and is based in Cambridge.

Location

Meditrina Building
Babraham Research Campus
Cambridge
Cambridgeshire
CB22 3AT
United Kingdom

Contact

Phone: +44 (0)1223 497 390
Fax: +44 (0)7798 791 337
Email: johntite@bicycletherapeutics.com


News Articles [763 Associated News Articles listed on BioPortfolio]

Bicycle Therapeutics to Present at Jefferies 2018 Global Healthcare Conference

Bicycle Therapeutics, a biotechnology company pioneering a new class of therapeutics based on its proprietary bicyclic peptide (Bicycle®) product platform, announced today that m...

Bicycle Therapeutics to Present at Cowen and Company 38th Annual Health Care Conference

Bicycle Therapeutics, a biotechnology company pioneering a new class of therapeutics based on its proprietary bicyclic peptide (Bicycle®) product platform, announced today that K...

AstraZeneca expands development deal with Bicycle

Aiming to bolster its respiratory and cardio-metabolic pipeline, the British pharma has broadened its collaboration with Bicycle to include more targets.

AstraZeneca expands alliance with Bicycle Therapeutics

Collaboration to seek out new respiratory and cardio-metabolic drugs

Bicycle Therapeutics, AstraZeneca Expand Collaboration

The 2016 partnership will now include additional targets in respiratory and cardio-metabolic diseases

Bicycle Therapeutics Expands Strategic Partnership with AstraZeneca

New programs added in respiratory and cardio-metabolic diseases Bicycle Therapeutics, a biotechnology company pioneering a new class of therapeutics based on its proprietary b...

Bicycle Therapeutics Promotes Michael Skynner, Ph.D., to Chief Operating Officer

Bicycle Therapeutics, a biotechnology company pioneering a new class of therapeutics based on its proprietary bicyclic peptide (Bicycle®) product platform, announced today the pr...

Bicycle Therapeutics Announces Formation of Scientific Advisory Board

Members include experts in oncology, immunology, and drug discovery and development Bicycle Therapeutics, a biotechnology company pioneering a new class of therapeutics...

PubMed Articles [465 Associated PubMed Articles listed on BioPortfolio]

Bicycle helmets - To wear or not to wear? A meta-analyses of the effects of bicycle helmets on injuries.

A meta-analysis has been conducted of the effects of bicycle helmets on serious head injury and other injuries among crash involved cyclists. 179 effect estimates from 55 studies from 1989-2017 are in...

Injuries to Cyclists due to a Dog-Bicycle Interaction.

 Both dogs and bicycles are common in our society and thus a dog-bicycle interaction resulting in an injury to a cyclist is possible. It was the purpose of this study to investigate such injuries.

Spatial variability of on-bicycle black carbon concentrations in the megacity of São Paulo: A pilot study.

In 2015, a controversial bicycle lane was installed on Paulista Avenue -a thoroughfare in the heart of the megacity of São Paulo with a high rate of motorised vehicles. For the first time, on-bicycle...

State Safe Bicycle Passing Laws.

(1) There were 840 bicyclist traffic deaths in 2016, the highest amount since 1991. (2) According to the Insurance Institute of Highway Safety, 45 percent of fatal bicycle crashes between 2008 and 201...

Identification of pre-impact conditions of a cyclist involved in a vehicle-bicycle accident using an optimized MADYMO reconstruction combined with motion capture.

The aim of the present study was to develop an improved method, using MADYMO multi-body simulation software combined with an optimization method and three-dimensional (3D) motion capture, for identify...

Clinical Trials [215 Associated Clinical Trials listed on BioPortfolio]

Bikes For Life: Measuring the Effects of a Bicycle Distribution Program on Pediatric Obesity

The investigators propose a study to evaluate the success of a bicycle distribution program in increasing physical activity level, decreasing sedentary activity levels and positively affec...

Nurse Managed Sequential Strength Training and Bicycle Training in Chronic Obstructive Pulmonary Disease (COPD)

This is a 16 week exercise training program for people with severe to very severe chronic obstructive pulmonary disease (COPD). The purpose of this study is to find out if performing stren...

Measuring Ability of Volunteers to Power a Bicycle-powered Oxygen Concentrator

We would like to test how well human volunteers power a modified oxygen concentrator. We modified the oxygen concentrator to be powered by a bicycle instead of wall power so that it can be...

Intelligent Electric Bicycle for Health (VELIS) to Optimize the Return to Physical Activity for Oncology Patients

The purpose of this pilot study is to encourage oncology patients to continue effort retraining after their release from rehabilitation and recuperative care facilities with physical activ...

Bicycle Simulator Training in Older Adults: A Randomized Controlled Trial

A Randomized Control Trial will be conducted with Independent old adults (age 70 years old and older) who willing to participate in the study. They will be randomly allocated to two groups...

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Bicycle Therapeutics Ltd

Bicycle Therapeutics is a biotechnology company based at the Babraham Research Campus in Cambridge, U.K. developing a novel technology for the creation of a new generation of biot...

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More Information about "Bicycle Therapeutics Ltd." on BioPortfolio

We have published hundreds of Bicycle Therapeutics Ltd. news stories on BioPortfolio along with dozens of Bicycle Therapeutics Ltd. Clinical Trials and PubMed Articles about Bicycle Therapeutics Ltd. for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Bicycle Therapeutics Ltd. Companies in our database. You can also find out about relevant Bicycle Therapeutics Ltd. Drugs and Medications on this site too.

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