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Bicycle Therapeutics Ltd. Company Profile

15:41 EDT 23rd June 2018 | BioPortfolio

Bicycle Therapeutics is a biotechnology company developing a platform technology that enables the creation of a new generation of biotherapeutics which combine the desirable features of small molecules and biopharmaceuticals to create highly specific and highly stable drugs.

Applying phage selection techniques to repertoires of chemically constrained cyclic peptides allows the identification and optimisation of molecules with high target specificity and binding affinity that are also stable to unfolding and to the action of proteases. These peptides could be regarded as a mini-antibodies with covalent organic cores, and as such should overcome the weaknesses of previous generations of peptide based therapeutics.

Bicycle Therapeutics is a spin-out from the Medical Research Council Laboratory of Molecular Biology, Cambridge, based on the pioneering work of the founding scientists Sir Gregory Winter and Dr.Christian Heinis. Bicycle Therapeutics is managed by Dr. John Tite (Chief Executive Officer) and is based in Cambridge.

Location

Meditrina Building
Babraham Research Campus
Cambridge
Cambridgeshire
CB22 3AT
United Kingdom

Contact

Phone: +44 (0)1223 497 390
Fax: +44 (0)7798 791 337
Email: johntite@bicycletherapeutics.com


News Articles [826 Associated News Articles listed on BioPortfolio]

Bicycle’s First Peptide-Toxin Conjugate Enters the Clinic for Solid Tumors

A collaboration between Bicycle Therapeutics and Cancer Research UK has yielded its first peptide to enter clinical trials for solid tumors. Bicycle Therapeutics, the pioneer of the bicyclic peptide p...

Bicycle, CR UK launch first trial of a bicyclic peptide

Bicycle Therapeutics and Cancer Research UK have initiated the first clinical study to assess a bicyclic peptide, evaluating its potential in patients with advanced solid tumours.

Bicycle Therapeutics to Present at Jefferies 2018 Global Healthcare Conference

Bicycle Therapeutics, a biotechnology company pioneering a new class of therapeutics based on its proprietary bicyclic peptide (Bicycle®) product platform, announced today that m...

Bicycle Therapeutics to Present at Cowen and Company 38th Annual Health Care Conference

Bicycle Therapeutics, a biotechnology company pioneering a new class of therapeutics based on its proprietary bicyclic peptide (Bicycle®) product platform, announced today that K...

AstraZeneca expands development deal with Bicycle

Aiming to bolster its respiratory and cardio-metabolic pipeline, the British pharma has broadened its collaboration with Bicycle to include more targets.

AstraZeneca expands alliance with Bicycle Therapeutics

Collaboration to seek out new respiratory and cardio-metabolic drugs

Bicycle Therapeutics, AstraZeneca Expand Collaboration

The 2016 partnership will now include additional targets in respiratory and cardio-metabolic diseases

Bicycle Therapeutics Expands Strategic Partnership with AstraZeneca

New programs added in respiratory and cardio-metabolic diseases Bicycle Therapeutics, a biotechnology company pioneering a new class of therapeutics based on its proprietary b...

PubMed Articles [465 Associated PubMed Articles listed on BioPortfolio]

Bicycle helmets - To wear or not to wear? A meta-analyses of the effects of bicycle helmets on injuries.

A meta-analysis has been conducted of the effects of bicycle helmets on serious head injury and other injuries among crash involved cyclists. 179 effect estimates from 55 studies from 1989-2017 are in...

bicycle: a bioinformatics pipeline to analyze bisulfite sequencing data.

High-throughput sequencing of bisulfite-converted DNA is a technique used to measure DNA methylation levels. Although a considerable number of computational pipelines have been developed to analyze su...

Injuries to Cyclists due to a Dog-Bicycle Interaction.

 Both dogs and bicycles are common in our society and thus a dog-bicycle interaction resulting in an injury to a cyclist is possible. It was the purpose of this study to investigate such injuries.

Epidemiology and Risk Factors for Bicycle-Related Severe Head Injury: A Single Center Experience.

Head injury is the main cause of death and severe disability in bicycle-related injuries. The purpose of this study was to compare the demographic characteristics and injury mechanisms of bicycle-rela...

Evaluating the impact of Mobike on automobile-involved bicycle crashes at the road network level.

As a booming system, free-floating bicycle-sharing (denoted as Mobike) attracts a large number of users due to the convenient utilization procedure. However, it brings about a rapid increase of bicycl...

Clinical Trials [198 Associated Clinical Trials listed on BioPortfolio]

Nurse Managed Sequential Strength Training and Bicycle Training in Chronic Obstructive Pulmonary Disease (COPD)

This is a 16 week exercise training program for people with severe to very severe chronic obstructive pulmonary disease (COPD). The purpose of this study is to find out if performing stren...

Measuring Ability of Volunteers to Power a Bicycle-powered Oxygen Concentrator

We would like to test how well human volunteers power a modified oxygen concentrator. We modified the oxygen concentrator to be powered by a bicycle instead of wall power so that it can be...

Intelligent Electric Bicycle for Health (VELIS) to Optimize the Return to Physical Activity for Oncology Patients

The purpose of this pilot study is to encourage oncology patients to continue effort retraining after their release from rehabilitation and recuperative care facilities with physical activ...

Impact of Ibis on Patients With Advanced COPD

The purpose of this research is to determine if Ibis™, a digital therapeutics solution developed by Senscio Systems, reduces the emergency room visits and hospitalizations of patients wi...

HDL Acute Lipid Optimization in Homozygous Familial Hypercholesterolemia

Assess the effect on coronary atheroma of serial infusions of autologous selectively delipidated HDL/preβ enriched plasma following use of HDL Therapeutics PDS-2™ System

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Bicycle Therapeutics Ltd

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More Information about "Bicycle Therapeutics Ltd." on BioPortfolio

We have published hundreds of Bicycle Therapeutics Ltd. news stories on BioPortfolio along with dozens of Bicycle Therapeutics Ltd. Clinical Trials and PubMed Articles about Bicycle Therapeutics Ltd. for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Bicycle Therapeutics Ltd. Companies in our database. You can also find out about relevant Bicycle Therapeutics Ltd. Drugs and Medications on this site too.

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