Bicycle Therapeutics Ltd. Company Profile

17:30 EST 24th November 2017 | BioPortfolio

Bicycle Therapeutics is a biotechnology company developing a platform technology that enables the creation of a new generation of biotherapeutics which combine the desirable features of small molecules and biopharmaceuticals to create highly specific and highly stable drugs.

Applying phage selection techniques to repertoires of chemically constrained cyclic peptides allows the identification and optimisation of molecules with high target specificity and binding affinity that are also stable to unfolding and to the action of proteases. These peptides could be regarded as a mini-antibodies with covalent organic cores, and as such should overcome the weaknesses of previous generations of peptide based therapeutics.

Bicycle Therapeutics is a spin-out from the Medical Research Council Laboratory of Molecular Biology, Cambridge, based on the pioneering work of the founding scientists Sir Gregory Winter and Dr.Christian Heinis. Bicycle Therapeutics is managed by Dr. John Tite (Chief Executive Officer) and is based in Cambridge.


Meditrina Building
Babraham Research Campus
CB22 3AT
United Kingdom


Phone: +44 (0)1223 497 390
Fax: +44 (0)7798 791 337

News Articles [583 Associated News Articles listed on BioPortfolio]

A €344M Partnership will Develop Bicycle Drugs for Hemophilia

Bicycle Therapeutics has partnered with Bioverativ to develop a new class of drugs for patients with rare blood disorders like hemophilia and sickle cell disease. Bicycle Therapeutics, a money-magnet ...

Bioverativ and Bicycle Therapeutics partner on hemophilia and sickle cell disease

Biotech companies Bioverativ and Bicycle Therapeutics, based in the USA and UK respectively, have entered…

Bioverativ and Bicycle Therapeutics Enter into Strategic Research Collaboration to Develop ...

Bicycle to receive an upfront payment of $10 million, with potential for future milestones Read more...

Bioverativ, Bicycle Partner to Develop Bicyclic Peptides for Blood Disorders

Blood disorder therapeutics firm, Bioverativ, which was spun out from Biogen earlier this year, announced a research collaboration with Bicycle Therapeutics focused on developing and commercializing n...

Bioverativ and Bicycle Therapeutics to develop new haemophilia and sickle cell disease treatments

US biotechnology company Bioverativ has entered a new research collaboration with UK-based Bicycle Therapeutics to discover, develop and commercialise new therapies for haemophilia and sickle cell dis...

Bioverativ, Bicycle Therapeutics to develop therapies for hemophilia and sickle cell disease

Bioverativ and Bicycle Therapeutics have announced a research collaboration focused on the discovery, development and commercialization of innovative therapies for hemophilia and sickle cell disease.

Bicycle Partners With Biogen Spinout Against Rare Blood Disorders

Bicycle Therapeutics and Biogen spinoff Bioverativ have teamed up to develop novel treatments for hemophilia and sickle cell disease under...   

Bioverativ partners with Bicycle to discover new hemophilia and sickle cell treatments

Bioverativ Inc. and Bicycle Therapeutics Ltd. teamed up to discover and develop bicyclic peptide therapies for hemophilia and sickle cell disease.

PubMed Articles [456 Associated PubMed Articles listed on BioPortfolio]

How bicycle level of traffic stress correlate with reported cyclist accidents injury severities: A geospatial and mixed logit analysis.

Transportation agencies need efficient methods to determine how to reduce bicycle accidents while promoting cycling activities and prioritizing safety improvement investments. Many studies have used s...

Commuting mode specific exposure to PM(2.5) in urban area of Guangzhou.

Objective: To find the differences in PM(2.5) exposure level in the context of four commuting modes (by walk, bicycle, bus and subway) in Guangzhou. Methods: The PM(2.5) exposure assessment was carrie...

Using local knowledge and sustainable transport to promote a greener city: The case of Bucharest, Romania.

Cities undergoing climate change and rapid urbanization are faced with significant transformational processes that affect the environment and society, challenging them to become more sustainable and r...

Trends in the incidence and outcomes of bicycle-related injury in the emergency department: A nationwide population-based study in South Korea, 2012-2014.

This study aimed to examine trends in the incidence and outcomes of bicycle-related injuries in emergency departments (ED) in South Korea.

Driver braking behavior analysis to improve autonomous emergency braking systems in typical Chinese vehicle-bicycle conflicts.

Bicycling is one of the fundamental modes of transportation especially in developing countries. Because of the lack of effective protection for bicyclists, vehicle-bicycle (V-B) accident has become a ...

Clinical Trials [167 Associated Clinical Trials listed on BioPortfolio]

Nurse Managed Sequential Strength Training and Bicycle Training in Chronic Obstructive Pulmonary Disease (COPD)

This is a 16 week exercise training program for people with severe to very severe chronic obstructive pulmonary disease (COPD). The purpose of this study is to find out if performing stren...

Measuring Ability of Volunteers to Power a Bicycle-powered Oxygen Concentrator

We would like to test how well human volunteers power a modified oxygen concentrator. We modified the oxygen concentrator to be powered by a bicycle instead of wall power so that it can be...

Intelligent Electric Bicycle for Health (VELIS) to Optimize the Return to Physical Activity for Oncology Patients

The purpose of this pilot study is to encourage oncology patients to continue effort retraining after their release from rehabilitation and recuperative care facilities with physical activ...

Impact of Ibis on Patients With Advanced COPD

The purpose of this research is to determine if Ibis™, a digital therapeutics solution developed by Senscio Systems, reduces the emergency room visits and hospitalizations of patients wi...

HDL Acute Lipid Optimization in Homozygous Familial Hypercholesterolemia

Assess the effect on coronary atheroma of serial infusions of autologous selectively delipidated HDL/preβ enriched plasma following use of HDL Therapeutics PDS-2™ System

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