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Oxford Molecular provides software tools and collaborative research services for identifying and optimizing drug candidates from biological targets. New automated technologies in genomics, high-throughput screening and combinatorial chemistry offer solutions for increasing the quantity and quality of pre-clinical drug candidates. Oxford Molecular helps companies to realize the benefits of these new technologies in the following areas:
Oxford Molecular is a leading supplier of software solutions for bioinformatics, including data services. Our bioinformatics products include the GCG Wisconsin Package™ and its two interfaces: SeqWeb™ for your web browser, and SeqLab® for X Windows. For the desktop, we offer OMIGA for Windows® and MacVector™ for the Macintosh. We also offer DataServe™, a convenient FTP service allowing pre-formatted downloads of public sequence databases. Finally, there is GENESEQ™ for comprehensive searching of patent sequences obtained from over 40 patent–issuing authorities worldwide.
New bioinformatics products include SeqStore™, which uses an Oracle® framework to integrate public, proprietary and in-house data across your company. Also new is OMIGA-GCG™, which enables users to search and retrieve sequence data from GCG Wisconsin Package databases and then perform sequence analysis within OMIGA’s Windows-based environment.
Oxford Molecular’s RS3 Discovery™ is an enterprise-wide research information solution using Oracle. RS3 manages the deluge of data from high-throughput screening and combinatorial chemistry synthesis. It can also assist in rapidly analyzing results and efficiently sharing verified data throughout the organization.
We also offer DIVA, an innovative visual tool for analyzing structures, properties and assay data. DIVA helps identify significant new entities from among thousands of compounds.
Oxford Molecular provides Chem-X™ for combinatorial library registration and lead generation. Its pharmacophore-based tools simplify library comparison and virtual screening.
Oxford Molecular helps scientists to discover relationships between molecular structure and activity, understand reactions and interactions between molecules, predict properties of new molecules, determine biological activity and assess toxicity—before expensive laboratory work is undertaken.
CAChe™ is a family of molecular modeling products for Macintosh and Windows desktop computers. Its award-winning user interface lets experimental chemists easily visualize molecules and reactions as well as predict and compare their chemical and physical properties.
For more sophisticated analysis, Oxford Molecular offers a suite of structure-activity programs for SGI workstations:
Tsar™ displays structures and properties in a spreadsheet form and performs a variety of statistical analyses. Tsar can also automatically substitute R-groups to define compounds.
Corina™ converts 2D structures to 3D.
Asp™ automatically aligns molecules for visual comparison.
Topkat® QSTRS provides quantitative assessment of toxicity from structure
Vamp™ performs semi-empirical quantum mechanics calculations to predict a variety of chemical and physical properties.
Oxford Molecular’s Collaborative Discovery division uses its expertise in informatics and drug design to accelerate the drug discovery process for clients in pharmaceutical and biotechnology companies. This expertise is complemented by the chemical synthesis skills of Cambridge Combinatorial and the advanced screening capabilities of Cambridge Drug Discovery. As a result, we are able to provide integrated, cost-effective solutions for target identification and validation, lead identification, and lead optimization.
Collaborative Discovery personnel have successfully managed and completed a wide range of multidisciplinary research collaborations. They bring together significant drug discovery experience in industry while also providing access to leading academic institutions through their relationships with key individuals. Our partners experience the benefits of new technologies while saving time and avoiding the cost of developing or supplementing internal resources.
For further information, please contact Oxford Molecular:
Oxford Molecular Group PLC, Medawar Centre, Oxford Science Park, Oxford OX4 4GA, UK; tel: +44 1865 784600; fax: +44 1865 784601; web site http://www.oxmol.co.uk
Oxford Molecular Group, Inc., 2105 South Bascom Ave., Suite 200, Campbell, CA 95008, USA; tel: 1-408-879-6300 or 1-800-876-9994; fax: 1-408-879-6302; web site: http://www.oxmol.com
2105 South Bascom Avenue Suite 200
United States of America
Phone: 408 879 6300
Fax: 408 879 6302
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