Pain Therapeutics Company Profile

05:27 EST 18th November 2017 | BioPortfolio

Pain Therapeutics, Inc. is a medical research company whose mission is to develop a new generation of opioid drugs (‘narcotic painkillers’). PTI has five active INDs and is focusing its Phase II development efforts on two lead compounds:

MorViva™ - a substitute for morphine and other strong opioids, and

OxyTrex™ - a substitute for oxycodone and other moderately strong opioids

The Company has two additional drug candidates, PTI-601 and PTI-701, which are also being developed.

An opioid drug (sometimes called a ‘narcotic painkiller’) refers to any drug that is derived from the opium poppy plant. This class of drugs is widely used throughout the world to treat clinical pain. In the U.S., for example, the market for narcotic painkillers exceeded $3 billion and accounted for over 5 percent of all prescription drug sales in the year 2001.

Despite widespread clinical use of narcotic painkillers, the under-treatment of pain is a serious and growing problem. For example, according to the National Institutes of Health, over 40 million Americans are unable to find relief from their pain. Conventional narcotic painkillers have debilitating side effects that limit their usefulness at all doses. In addition, chronic use of conventional narcotic painkillers may lead to tolerance, dependence, abuse, or, very rarely, addiction. As a result, some patients prefer to suffer through pain rather than to endure the ill effects of conventional narcotic painkillers.


416 Browning Way
San Francisco
United States of America


Phone: 650-624-8200
Fax: 650-624-8222

News Articles [1417 Associated News Articles listed on BioPortfolio]

Pain Therapeutics May 23-24 2016, London, UK

Many research studies show, pain is a significant source of suffering for many people and seriously affects their quality of life. Treatment of these patients is a great challenge and requires special...

NIH grants $4M to Pain Therapeutics for Alzheimer's blood test, fentanyl patch

The NIH awarded a $4 million grant to Pain Therapeutics to support the company's development of an Alzheimer's disease blood  -More- 

STAT Plus: Nektar Therapeutics reports progress in making an opioid pain pill that addicts don’t much like

A novel opioid from Nektar Therapeutics crosses the blood-brain barrier slowly, so it relieves pain but is harder to abuse.Trial results are promising.

STAT Plus: Nektar Therapeutics reports progress in making an opioid pain pill that drug users don’t much like

A novel opioid from Nektar Therapeutics crosses the blood-brain barrier slowly, so it relieves pain but is harder to abuse.Trial results are promising.

Antibe Therapeutics Inc., Safe Pain and Inflammation Medicine, CEO Clip Video

Vancouver, British Columbia--(Newsfile Corp. - September 13, 2017) - Dan Legault, CEO of Antibe Therapeutics Inc., on the company's best-in-class pain/inflammation and regenerative medicine divisio...

Ketamine Metabolites for the Treatment of Depression and Pain

The market continues to have a need for therapeutics for treating pain and depression that have efficacy in a high percentage of patients but have reduced anaesthetic properties and reduced abuse liab...

Centrexion To Present Clinical Data From Pipeline Of Chronic Pain Treatments At The 11th Annual Pain And Migraine Therapeutics Summit

  Life Sciences Jobs   ...

2 contrasting medtech approaches to deal with chronic pain and avoid opioids

Medtronic and SPR Therapeutics are treating chronic pain but while the former has adopted a permanent, implantable neuromodulation treatment, the latter is going the temporary wearable route.

PubMed Articles [2891 Associated PubMed Articles listed on BioPortfolio]

From Mechanism to Cure: Renewing the Goal to Eliminate the Disease of Pain.

Persistent pain causes untold misery worldwide and is a leading cause of disability. Despite its astonishing prevalence, pain is undertreated, at least in part because existing therapeutics are ineffe...

Progress and challenges in the optimization of toxin peptides for development as pain therapeutics.

The number of new toxin peptide discoveries has been rapidly growing in the past few decades. Because of progress in proteomics, sequencing technologies, and high throughput bioassays, the search for ...

Headache Exacerbates Pain Characteristics in Temporomandibular Disorders.

To evaluate the impact of headache in adults with masticatory myofascial pain (MMP) on the outcome variables clinical pain (ie, self-reported pain intensity and pressure pain sensitivity), sleep quali...

Increased deep pain sensitivity in persistent musculoskeletal pain but not in other musculoskeletal pain states.

Pressure pain thresholds (PPTs) in a non-painful body area are known to be affected in some chronic pain states. The aim of this study is to investigate PPTs in a pain-free body part in relation to pa...

Moving beyond pain scores: Multidimensional pain assessment is essential for adequate pain management after surgery.

Clinical experience teaches us that patients are willing to accept postoperative pain, despite high pain intensity scores. Nevertheless, relationships between pain scores and other methods of pain ass...

Clinical Trials [4820 Associated Clinical Trials listed on BioPortfolio]

Impact of Ibis on Patients With Advanced COPD

The purpose of this research is to determine if Ibis™, a digital therapeutics solution developed by Senscio Systems, reduces the emergency room visits and hospitalizations of patients wi...

Interest of Pain Assessment by the Family of Patients in Limiting and Stopping Active Treatment Process Admitted in ER. Study DOFAMILA

Decisions to limit and stop active therapeutics are common in the emergency unit. They are framed by the Leonetti law of 22 April 2005 recommending the refusal of unreasonable obstinacy an...

HDL Acute Lipid Optimization in Homozygous Familial Hypercholesterolemia

Assess the effect on coronary atheroma of serial infusions of autologous selectively delipidated HDL/preβ enriched plasma following use of HDL Therapeutics PDS-2™ System

Ontogenesis of the P-Glycoprotein in Human Lymphocytes Influence of HIV and Antiretroviral Therapeutics

The P-glycoprotein (P-gp) is a membranous transporter that modulates the intracellular concentrations of many drugs and plays thus a major role in the efficacy of the therapeutics that act...

A Trial to Find Safe and Active Doses of an Investigational Drug CX-072 for Patients With Solid Tumors or Lymphomas

The purpose of this first-in-human study of CX-072 is to characterize the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) and antitumor activity of CX-072 administered i...

Companies [1699 Associated Companies listed on BioPortfolio]

Centrexion Therapeutics

Centrexion Therapeutics, Inc., is focused on developing and commercializing new, non-opioid and non-surgical treatments for moderate to severe chronic pain. Centrexion Therapeutic...

Centrexion Therapeutics, Corp.

Centrexion Therapeutics, Corp. is focused on advancing the treatment of chronic moderate to severe pain with one of the largest exclusively pain-focused pipelines of non-...

CNS Therapeutics

Founded in 2007 by recognized experts in intrathecal drug therapies, CNS Therapeutics is a private company based in St. Paul, Minnesota. CNS Therapeutics develops and markets safe...

Algos Therapeutics, Inc

Algos Therapeutics is a privately held, independent research company specializing in the evaluation of potential pain treatments under development. The data we generate from our models have proven hig...

The Rosomoff Comprehensive Pain Center (RCPC)

The Rosomoff Comprehensive Pain Center (RCPC) is a state-of-the-art Center of Excellence offering inpatient, outpatient, outpatient rehabilitation services and seniors programs. Founded in 1974 as the...

More Information about "Pain Therapeutics" on BioPortfolio

We have published hundreds of Pain Therapeutics news stories on BioPortfolio along with dozens of Pain Therapeutics Clinical Trials and PubMed Articles about Pain Therapeutics for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Pain Therapeutics Companies in our database. You can also find out about relevant Pain Therapeutics Drugs and Medications on this site too.

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Pain is defined by the International Association for the Study of Pain as “an unpleasant sensory and emotional experience associated with actual or potential tissue damage or described in terms of such damage”. Some illnesses can be excruci...

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