Plexus Vaccine Incorporated Company Profile

14:35 EST 21st November 2017 | BioPortfolio

Plexus employs powerful proprietary tools of computational protein structural biology combined with genomic bioinformatics analysis and the principles of rational drug design to create vaccines that induce specific mechanistic interventions in critical protein functions. For the first time, epitope-specific vaccines that generate neutralizing antibodies can be designed and synthesized from deduction and mimicry of the 3D structural features of epitopes, applying sophisticated methods of structure-based drug design.

The work is exploiting broadly protective epitopes revealed from our comparative structural analysis of vast numbers of genetic variants (polymorphisms) of pathogens. The Company applies proprietary advanced bioinformatics analysis against entire genomes of pathogens and their host species to find a new generation of safe and effective vaccines, with the mission of rapidly delivering robust protection from serious disease through its enabling technology and novel vaccine products for human and veterinary markets.


11770 Bernardo Plaza Court, Suite 370-B
San Diego
United States of America


Phone: 858 385 9084
Fax: 858 385 9086

News Articles [1192 Associated News Articles listed on BioPortfolio]

Inflammation-dependent cerebrospinal fluid hypersecretion by the choroid plexus epithelium in posthemorrhagic hydrocephalus

In a rat model of hydrocephalus triggered by intraventricular hemorrhage, Kristopher Kahle and colleagues show that TLR4–NF-κB-dependent inflammatory signaling in the choroid plexus causes hypersec...

An Adjuvanted Subunit Zoster Vaccine Gets a Response (FREE)

The immunogenicity and safety profile of the novel vaccine were similar in those who had previously received the live attenuated vaccine compared with those who were vaccine-naive.

‘Universal flu vaccine’ to be trialed this winter

Researchers are enrolling 500 participants for the trial of a flu vaccine to protect the population against all strains of the flu virus. The push to bring the vaccine to patients has been given more...

‘Universal flu vaccine’ to be trialled this winter

Researchers are enrolling 500 participants for the trial of a flu vaccine to protect the population against all strains of the flu virus. The push to bring the vaccine to patients has been given more...

A short history of vaccine objection, vaccine cults and conspiracy theories

When we hear phrases like vaccine objection, vaccine refusal and anti-vaxxers, it's easy to assume these are new labels used in today's childhood vaccination debates.

During Vaccine Awareness Week, National Vaccine Information Center Reports No Loss of Vaccine ...

National Vaccine Information CenterBarbara Loe Fisher, 703-938-0342

Correction: FDA-Shingles Vaccine story

In a story Oct. 20 about U.S. approval of GlaxoSmithKline's shingles vaccine, The Associated Press reported erroneously that the drugmaker is testing its new vaccine against an older one sold by M...

When voting to approve a new vaccine, if you don’t know, say so

I abstained from an FDA committee vote on the safety of a new vaccine because it was impossible to tell if the vaccine increases heart attack risk.

PubMed Articles [1089 Associated PubMed Articles listed on BioPortfolio]

Anatomical variations of brachial plexus in fetal cadavers.

The plexus brachialis is a complex structure with anatomical variations and connections with neighboring tissues. These variations may cause disparity in the motor and sensorial innervations of the up...

Hourglass-Like Constriction of the Brachial Plexus in the Posterior Cord: A Case Report.

Hourglass-like constrictions are fascicular conditions confirmed definitively by interfascicular neurolysis. Certain peripheral nerves have vulnerable areas such as around the elbow in the posterior i...

Bivalent vaccine effectiveness against type-specific HPV positivity: evidence for cross-protection against oncogenic types among Dutch STI clinic visitors.

Observational post-marketing studies are important to assess vaccine effectiveness (VE). We estimated VE from the bivalent human papillomavirus (HPV) vaccine against HPV positivity of vaccine and non-...

Postoperative analgesia comparing levobupivacaine and ropivacaine for brachial plexus block: A randomized prospective trial.

On a pharmacologic basis, levobupivacaine is expected to last longer than ropivacaine. However, most reports of these anesthetics for brachial plexus block do not suggest a difference in analgesic eff...

Efficacy of Phase 3 Trial of RTS, S/AS01 Malaria Vaccine: The Need for an Alternative Development Plan.

Although vaccines would be the ideal tool for control, prevention, elimination, and eradication of many infectious diseases, developing of parasites vaccines such as malaria vaccine is very complex. T...

Clinical Trials [3215 Associated Clinical Trials listed on BioPortfolio]

Comparison of Two Different Procedures for Plexus Anesthesia

The purpose of this study is to investigate the influence of difference positioning on extension and efficacy of brachial plexus anesthesia at 20 minutes by using the axillary plexus block...

Clinical Research of Retrograde Infraclavicular Brachial Plexus Blockade

Brachial plexus block is a frequently used technique for upper extremity surgery. All present approaches and techniques have certain advantages and disadvantages. It's necessary to develop...

Superficial Cervical Plexus Blockade for Clavicle Fracture Analgesia

The goal of the study is to determine if the addition of a superficial cervical plexus block to a traditional interscalene plexus block will provide superior perioperative analgesia to an ...

The Perioperative Analgesic Efficiency of Bilateral Superficial Cervical Plexus Block in Patients With Thyroidectomy

To determine the postoperative analgesic efficiency of bilateral superficial plexus block, patients are divided into two groups. Study group received bilateral superficial plexus block, wh...

Trial of Endoscopic Ultrasound (EUS) - Guided Celiac Plexus Neurolysis

Pancreatic cancer presents with pain in the majority of cases. Destruction of the celiac ganglia by ultrasound guided injection of sclerosing agents such as alcohol is sometimes used for p...

Companies [287 Associated Companies listed on BioPortfolio]

Plexus Systems, Inc.

Since 1995, Plexus Systems, Inc. (Auburn Hills, Mich.) has maintained a singular vision -- to drive significant cost, quality and productivity improvements for manufacturers, from the shop floor t...

PLEXUS Health and Casualty Services

Formed in 2010, PLEXUS Health and Casualty Services offers an alternative network solution to the quickly expanding self-insurance market. PLEXUS Health and Casualty Services help...

Plexus Vaccine Incorporated

Plexus employs powerful proprietary tools of computational protein structural biology combined with genomic bioinformatics analysis and the principles of rational drug design to create vaccines that i...

Plexus Management Group, LLC

Plexus Management Group, LLC, a subsidiary of MiraMed Global Services, is a management services organization that identifies and solves the technical, operational, and strategic c...

Plexus Legal Demonstrative Exhibits

Established in 1995, Plexus has been creating sophisticated demonstrative evidence exhibits which clearly communicate the facts and legal assertions that are germane to the attorney's legal arguments....

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