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Replicon Technologies Incorporated Company Profile

02:30 EST 23rd November 2017 | BioPortfolio

Replicon Technologies, Inc. (RTI) is an emerging biotechnology company focused on the use of replicons, non-replicating RNA viral particles, for the treatment of patients with cancer. RTI is founded on research and development performed at the University of Alabama at Birmingham (UAB), and supported by competitive grants from the National Institutes of Health, the Department of Defense, and SBIR grants from the National Cancer Institute.

RTI’s replicons are oncolytic in a broad range of cancers, can cross the blood brain barrier, and efficiently diffuse through CNS tissue to sites of metastases. Replicons are highly selective for tumors due to up-regulation of the poliovirus receptor (CD-155) on cancer cells. Product development is focused on treatment of patients with primary brain cancers and metastases of cancers to the CNS, an area of cancer treatment for which replicons are uniquely suited due to their natural tropism for CNS tissues. The CNS is an area where current therapeutic alternatives of chemotherapy and radiation are minimally effective and cause excessive morbidity. Moreover, there are few, if any, viable new therapies in development for the specialized area of treating brain metastases or cancers to the CNS.

Location

828 Eastbrook Court
Danville
CA
94505-1206
United States of America

Contact

Phone: (925) 736 1863
Fax: (925) 736 5910
Email: DCAnsardi@replicontechnologies.com


News Articles [198 Associated News Articles listed on BioPortfolio]

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Advanced Enzymes acquires evoxx

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Partnership agreement signed to combine epigenetics technologies

A partnership agreement has been entered into by Cambridge Epigenetix (CEGX) and NuGEN Technologies to cover the manufacture and integration of technologies for epigenetic research.

DBV Technologies: DBV Technologies Reports September 30, 2017 Cash Position

Press ReleaseMontrouge, France, October 31, 2017 DBV Technologies Reports September 30, 2017 Cash Position DBV Technologies (Euronext: DBV - ISIN: FR0010417345 - Nasdaq Stock Market: DBVT) today a...

Agilent acquires Cobalt, expanding value for pharma and biopharma

Specialist in analytical laboratory technologies, Agilent Technologies, has acquired Cobalt Light Systems, which develops products and technologies for non-invasive, through-barrier chemical analysis ...

AMS Technologies Extends Design Services with Acquisition of Elforlight

Acquisition strengthens company’s competence and expertise for solving the most challenging photonics applications  AMS Technologies, Europe’s leading solution provider and distributo...

Milimeter-wave technologies, the promise of 5G wireless communications

(IMDEA Networks Institute) IMDEA Networks and Huawei Technologies have recently launched a joint research project to explore the synergies of two distinctive wireless technologies, which are both key ...

PubMed Articles [361 Associated PubMed Articles listed on BioPortfolio]

Development of a stable Japanese encephalitis virus replicon cell line for antiviral screening.

Japanese encephalitis virus (JEV), an important pathogen in Eastern and Southern Asia and the Pacific, has spread to Australia and other territories in recent years. Although the vaccine for JEV has b...

Health technology assessments conducted in health care facilities: A strategic practice? Findings from a content analysis of HTA reports.

In this paper, we test the hypothesis that health technology assessment units located in hospitals tend to be more optimistic toward technologies that are currently in use in their organization than t...

Clonal diversity of extended-spectrum beta-lactamase producing Escherichia coli isolates in fecal samples of wild animals.

The clonal diversity of extended-spectrum-β-lactamase (ESBL)-producing Escherichia coli isolates from nine different species of wild animals from distinct regions of Portugal and Spain and their cont...

Enhancing the Gaming Experience Using 3D Spatial User Interface Technologies.

Three-dimensional (3D) spatial user interface technologies have the potential to make games more immersive and engaging and thus provide a better user experience. Although technologies such as stereos...

A brief review of single-cell transcriptomic technologies.

In recent years, there has been an effort to develop new technologies for measuring gene expression and sequence information from thousands of individual cells. Large data sets that were obtained usin...

Clinical Trials [332 Associated Clinical Trials listed on BioPortfolio]

A Clinical Trial of an Alphavirus Replicon Vaccine for Cytomegalovirus (CMV)

AVX601, a bivalent alphavirus replicon vaccine expressing three CMV proteins (gB, pp65 and IE1) is a candidate vaccine against cytomegalovirus (CMV). The objectives of this Phase 1 study ...

A Phase 1/2 Clinical Trial of an Alphavirus Replicon Vaccine for Influenza

AVX502, an alphavirus replicon vaccine expressing an influenza HA protein, is a candidate vaccine against influenza. The objectives of this Phase 1 study are to test the safety of the vac...

Application of Monitoring and Intervention Technologies in Suboptimal Health Status

The purpose of this study is to use monitoring and intervention technologies in suboptimal health status in a general population in China and evaluate the effectiveness of these technologi...

Wheeze Detection in Adults During Dynamic Bronchial Situations Measured by PulmoTrack® 2010 With WIM-PC™ Technologies Recording

The PulmoTrack® 2010 with WIM-PC™ Technologies device, indicated for acoustic pulmonary function measurement that quantifies the presence of wheezing. This study was designed in order t...

Testing Latest Version of NidekRS3000Adv

The investigators would like to know if different imaging devices can improve the quality of images and visualization of imaged tissues. Also, the investigators would like to find out whet...

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Replicon Technologies Incorporated

Replicon Technologies, Inc. (RTI) is an emerging biotechnology company focused on the use of replicons, non-replicating RNA viral particles, for the treatment of patients with cancer. RTI is founded ...

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SQI Diagnostics Inc.

SQI Diagnostics is a life sciences company that develops and commercializes proprietary technologies and products for advanced microarray diagnostics. The Company’s proprieta...

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We have published hundreds of Replicon Technologies Incorporated news stories on BioPortfolio along with dozens of Replicon Technologies Incorporated Clinical Trials and PubMed Articles about Replicon Technologies Incorporated for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Replicon Technologies Incorporated Companies in our database. You can also find out about relevant Replicon Technologies Incorporated Drugs and Medications on this site too.

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